Non-invasive Testing for NASH and NASH with Advanced Fibrosis: Are We There Yet? [0.03%]
非侵入性检测用于诊断NASH及伴晚期纤维化的NASH：我们准备好了吗？
Ahilan Arulanandan,Rohit Loomba
Ahilan Arulanandan
Nonalcoholic fatty liver disease (NAFLD) is the most prevalent etiology of chronic liver disease in America. NAFLD can be broadly classified in two subtypes: nonalcoholic fatty liver (NAFL), which is generally considered a benign condition ...
Claire Meyer,Mauricio Lisker-Melman
Claire Meyer
Hepatic adenomatosis and hepatocellular adenomas share risk factors and the same pathophysiologic spectrum. The presence in the liver of 10 hepatocellular adenomas defines hepatic adenomatosis. The diagnosis may be established incidentally ...
Screening for hepatocellular carcinoma and cholangiocarcinoma: Can biomarkers replace imaging? [0.03%]
肝细胞癌和胆管癌的筛查：生物标志物能取代影像学吗？
Maria E Lozada,Roongruedee Chaiteerakij,Lewis R Roberts
Maria E Lozada
PATHOGENESIS OF HEPATOCELLULAR CARCINOMA DEVELOPMENT IN NON ALCOHOLIC FATTY LIVER DISEASE [0.03%]
非酒精性脂肪肝病中肝细胞癌的发病机制研究进展
Kirti Shetty,Jian Chen,Ji-Hyun Shin et al.
Kirti Shetty et al.
Non-alcoholic fatty liver disease (NAFLD) is being recognized as an increasingly important contributor to the burden of hepatocellular carcinoma (HCC) worldwide. It is often accompanied by obesity and diabetes mellitus and is believed to be...
Anil Seetharam,Robert Perrillo,Robert Gish
Anil Seetharam
After hepatitis B virus (HBV) infection, HBV DNA persists in minute amounts in hepatocyte nuclei even in individuals with "resolved" infection. Viral replication and development of liver disease depend on the balance between viral mechanism...
Caroline C Duwaerts,Jacquelyn J Maher
Caroline C Duwaerts
Non-alcoholic steatohepatitis (NASH) is a disorder marked by alterations in hepatic lipid homeostasis as well as liver injury in the form of cell death, inflammation and fibrosis. Research into the pathophysiology of NASH is dynamic. New co...
Hepatic steatosis and steatohepatitis: Are they really two distinct entities? [0.03%]
肝脂肪变性和脂肪性肝炎：它们真的是两个不同的实体吗？
Cory M Fielding,Paul Angulo
Cory M Fielding
Non-alcoholic fatty liver disease affects nearly 30% of Americans. A histopathological spectrum exists from simple steatosis to NASH which may progress to cirrhosis and HCC. NASH is currently the third most common indication for liver trans...
Brett Fortune,Guadalupe Garcia-Tsao
Brett Fortune
Acute esophageal variceal hemorrhage is one of the clinical events that define decompensated cirrhosis and is associated with high rates of morbidity and mortality. Although recent treatment strategies have led to improved outcomes, varicea...