Navigating Chronic Pain in Patients with Cirrhosis: Unique Analgesic Considerations and Non-Pharmacologic Options [0.03%]
肝硬化患者慢性疼痛的管理：独特的镇痛注意事项和非药物治疗选项
Lisa X Deng,Jessica B Rubin
Lisa X Deng
Purpose of review: Chronic pain affects 40-80% of patients with chronic liver disease, yet management remains challenging due to impaired drug metabolism, limited evidence, and the absence of disease-specific guidelines. ...
Irina Adao,Arielle Klepper,Michele Tana
Irina Adao
Purpose of review: The purpose of the article is to review treatment options for patients with AIH for whom first-line therapy is not successful. We outline recommended approaches for providers and new therapies on the ho...
Transient Elastography and Fibroscan: Stethoscope of a Hepatologist in Today's World [0.03%]
瞬时弹性成像及FibroScan：当今肝病医师的听诊器
Sajid Jalil,Mangesh Pagadala,Nicholas Dunn et al.
Sajid Jalil et al.
Purpose of review: Vibration-controlled transient elastography (VCTE) has become a cornerstone in the noninvasive assessment of liver disease across etiologies. This review highlights its role in risk stratification and l...
Met-ALD and ALD- Does Differentiating These Impact Management and Clinical Outcomes? [0.03%]
代谢ALD和ALD-区分这些对管理和临床结果有影响吗？
Fatima Elmustafa,Mahima Tyagi,Harpreet Kaur et al.
Fatima Elmustafa et al.
Purpose of review: The new nomenclature of steatotic liver disease overcame the stigma associated with non-alcohol fatty liver disease term changing to metabolic dysfunction associated steatototic liver disease (MASLD), a...
Outcomes in Cirrhosis-Related Refractory Ascites with Emphasis on Palliative Care: Single-Centre Experience and Literature Review [0.03%]
难治性腹水的预后及以姑息治疗为重点的照护：单中心经验和文献回顾
Marcus Rex English,Jordache Ellis,Sumita Verma et al.
Marcus Rex English et al.
Purpose of review: Despite refractory ascites (RA) due to cirrhosis having a median transplant-free survival of 6-12 months, palliative care (PC) input remains uncertain. We aimed to review the existing literature on clin...
Alcohol-Associated Hepatitis: Translating Pathophysiology into Targeted Clinical Trials [0.03%]
酒精性肝炎：从病理生理学到靶向临床试验
Jing Ma,Hui Gao,Ge Zeng et al.
Jing Ma et al.
Purpose of review: Alcohol-associated hepatitis (AH) is a severe manifestation of alcohol-associated liver disease with high short-term mortality and limited treatment options. This review synthesizes mechanistic insights...
Hepatic Hydrothorax: A Review [0.03%]
肝性腹水概述
Abdellatif Ismail,Mohanad Awadalla,Suvisesh Pothuraju et al.
Abdellatif Ismail et al.
Purpose of the review: To review epidemiology, pathogenesis, diagnosis, and management of hepatic hydrothorax. Recent findings: Refract...
Pre-Operative Assessment of Patients with Cirrhosis for Extrahepatic Surgery [0.03%]
Child-Pugh评分系统在肝硬化患者行肝外手术中的应用及预后分析
Claire Durkin,Nadim Mahmud
Claire Durkin
Purpose of review: Patients with cirrhosis are at increased risk of peri-operative morbidity and mortality compared to those without cirrhosis, requiring careful pre-operative assessment of their liver disease, extra-hepa...
Perspective on Emerging Therapies to Achieve Functional Cure of Chronic Hepatitis B [0.03%]
实现慢性乙型肝炎功能性治愈的新兴疗法展望
Harish Gopalakrishna,Marc G Ghany
Harish Gopalakrishna
Purpose of review: Advancements in our understanding of the hepatitis B viral (HBV) life cycle have paved the way for novel approaches to treat HBV infection. This review summarizes the various strategies being pursued to...
Harish Gopalakrishna,Maria Mironova,Harel Dahari et al.
Harish Gopalakrishna et al.
Purpose of review: Hepatitis D Virus (HDV), although a small defective virus, poses a substantial public health challenge due to lack of awareness, underrecognized prevalence, and limited treatment options. Universal HDV ...