Hepatocellular Carcinoma in Africa: Epidemiology, Prevention and Outcomes [0.03%]
非洲的肝细胞癌：流行病学、预防和预后
Joseph A Akambase,Ponsiano Ocama,Jose D Debes
Joseph A Akambase
Purpose of review: This review synthesizes the current knowledge of hepatocellular carcinoma (HCC) epidemiology across Northern and sub-Saharan Africa. We examine how causes of HCC differ by region, highlight prevention a...
Navigating Chronic Pain in Patients with Cirrhosis: Unique Analgesic Considerations and Non-Pharmacologic Options [0.03%]
肝硬化患者慢性疼痛的管理：独特的镇痛注意事项和非药物治疗选项
Lisa X Deng,Jessica B Rubin
Lisa X Deng
Purpose of review: Chronic pain affects 40-80% of patients with chronic liver disease, yet management remains challenging due to impaired drug metabolism, limited evidence, and the absence of disease-specific guidelines. ...
Irina Adao,Arielle Klepper,Michele Tana
Irina Adao
Purpose of review: The purpose of the article is to review treatment options for patients with AIH for whom first-line therapy is not successful. We outline recommended approaches for providers and new therapies on the ho...
Transient Elastography and Fibroscan: Stethoscope of a Hepatologist in Today's World [0.03%]
瞬时弹性成像及FibroScan：当今肝病医师的听诊器
Sajid Jalil,Mangesh Pagadala,Nicholas Dunn et al.
Sajid Jalil et al.
Purpose of review: Vibration-controlled transient elastography (VCTE) has become a cornerstone in the noninvasive assessment of liver disease across etiologies. This review highlights its role in risk stratification and l...
Met-ALD and ALD- Does Differentiating These Impact Management and Clinical Outcomes? [0.03%]
代谢ALD和ALD-区分这些对管理和临床结果有影响吗？
Fatima Elmustafa,Mahima Tyagi,Harpreet Kaur et al.
Fatima Elmustafa et al.
Purpose of review: The new nomenclature of steatotic liver disease overcame the stigma associated with non-alcohol fatty liver disease term changing to metabolic dysfunction associated steatototic liver disease (MASLD), a...
Outcomes in Cirrhosis-Related Refractory Ascites with Emphasis on Palliative Care: Single-Centre Experience and Literature Review [0.03%]
难治性腹水的预后及以姑息治疗为重点的照护：单中心经验和文献回顾
Marcus Rex English,Jordache Ellis,Sumita Verma et al.
Marcus Rex English et al.
Purpose of review: Despite refractory ascites (RA) due to cirrhosis having a median transplant-free survival of 6-12 months, palliative care (PC) input remains uncertain. We aimed to review the existing literature on clin...
Alcohol-Associated Hepatitis: Translating Pathophysiology into Targeted Clinical Trials [0.03%]
酒精性肝炎：从病理生理学到靶向临床试验
Jing Ma,Hui Gao,Ge Zeng et al.
Jing Ma et al.
Purpose of review: Alcohol-associated hepatitis (AH) is a severe manifestation of alcohol-associated liver disease with high short-term mortality and limited treatment options. This review synthesizes mechanistic insights...
Hepatic Hydrothorax: A Review [0.03%]
肝性腹水概述
Abdellatif Ismail,Mohanad Awadalla,Suvisesh Pothuraju et al.
Abdellatif Ismail et al.
Purpose of the review: To review epidemiology, pathogenesis, diagnosis, and management of hepatic hydrothorax. Recent findings: Refract...
Pre-Operative Assessment of Patients with Cirrhosis for Extrahepatic Surgery [0.03%]
Child-Pugh评分系统在肝硬化患者行肝外手术中的应用及预后分析
Claire Durkin,Nadim Mahmud
Claire Durkin
Purpose of review: Patients with cirrhosis are at increased risk of peri-operative morbidity and mortality compared to those without cirrhosis, requiring careful pre-operative assessment of their liver disease, extra-hepa...
Perspective on Emerging Therapies to Achieve Functional Cure of Chronic Hepatitis B [0.03%]
实现慢性乙型肝炎功能性治愈的新兴疗法展望
Harish Gopalakrishna,Marc G Ghany
Harish Gopalakrishna
Purpose of review: Advancements in our understanding of the hepatitis B viral (HBV) life cycle have paved the way for novel approaches to treat HBV infection. This review summarizes the various strategies being pursued to...