Stigmasterol Tetracosanoate, a New Stigmasterol Ester from the Egyptian Blepharis ciliaris [0.03%]
来自埃及裂唇柱花草的新型固醇酯豆甾醇四cosaon酸酯
M A El-Shanawany,H M Sayed,S R M Ibrahim et al.
M A El-Shanawany et al.
A new stigmasterol ester: stigmasterol tetracosanoate (3), along with 7 compounds: β-sitosterol (1), stigmasterol (2), (2S,3S,4R)-2[(2'R)-2'-(hydroxyeicosanoyl amino) octadecane-1,3,4-triol (4), apigenin (5), β-sitosterol-3-O-β-D-glucopy...
K Arslan,M Kanbur,M Karabacak et al.
K Arslan et al.
In this study*, it was aimed to observe, genotoxic effects of antituberculosis drugs and combinations on rats. Animals were treated with 31.5 mg/kg isoniazid (INH), 54 mg/kg rifampicin (RIF), 189 mg/kg pyrazinamide (PYR), 100 mg/kg etham-bu...
Investigating the Potential Effect of Commiphora myrrha on the Pharmacokinetics of Theophylline, a Narrow Therapeutic Index Drug [0.03%]
没药对治疗指数窄的药物茶碱药代动力学潜在影响的研究
F I Al-Jenoobi,A Ahad,M Raish et al.
F I Al-Jenoobi et al.
Aim: The present study was conducted to investigate the effect of commonly used herb Commiphora myrrha on the pharmacokinetic profile of theophylline (narrow therapeutic index drug) in rabbits. ...
Evaluation of Antidepressant-like Effect of Olax Subscorpioidea Oliv. (Olacaceae) Extract in Mice [0.03%]
奥拉克属植物 Oliv．的抗抑郁作用评价
O A Adeoluwa,A O Aderibigbe,A G Bakre
O A Adeoluwa
Olax subscorpioidea is a shrub or tree found in Nigeria, and other parts of Africa. It is indicated in the management of inflammatory disorder, mental illness, convulsion, pain, and cancer.Based on the folkloric use in the management of men...
Protective Effects of Gallic Acid against Streptozotocin-induced Oxidative Damage in Rat Striatum [0.03%]
没食子酸对链脲佐菌素致大鼠纹状体氧化损伤的保护作用研究
B Naghizadeh,M T Mansouri
B Naghizadeh
The present study aimed to investigate the protective effects of gallic acid (GA) against ICV STZ-induced oxidative damage in the rat striatum. Animals were randomly divided into 4 groups (8 each). Group 1 (Sham), were injected ICV on day 1...
Paclitaxel and gemcitabine combinational drug-loaded mucoadhesive delivery system in the treatment of colon cancers [0.03%]
用于结肠癌治疗的多西他赛和吉西他滨联合用药黏附给药系统
X-Y Guo,P Wang,Q-G Du et al.
X-Y Guo et al.
The combination of two different types of chemo-therapeutic drugs via nanocarriers is emerged as a promising strategy for treating multiple cancers. Such a co-delivery system will synchronize the drug exposure and synergize the therapeutic ...
Two New Flavonoids and Biological Activity of Astragalus abyssinicus (Hochst.) Steud. ex A. Rich. Aerial Parts [0.03%]
Astragalus abyssinicus地上部分两种新黄酮及生物活性研究
R A El Dib,H S M Soliman,M H Hussein et al.
R A El Dib et al.
2 new flavonoid glycosides, kaempferol 3-O-(4",6"-di-O-α-L-rhamnopyranosyl)-β-D-glucopyranoside (1) and quercetin 3-O-(4",6"-di-O-α-L-rhamnopyranosyl)-β-D-glucopyranoside (2), were isolated from the n-butanol soluble fraction of the met...
A rapid and sensitive LC-MS/MS assay for the determination of saxagliptin and its active metabolite 5-hydroxy saxagliptin in human plasma and its application to a pharmacokinetic study [0.03%]
一种人血浆中萨格列汀及其活性代谢产物5-羟基萨格列汀的快速灵敏LC-MS/MS测定法及其在药代动力学研究中的应用
N Batta,N R Pilli,V R Derangula et al.
N Batta et al.
The authors proposed a simple, rapid and sensitive liquid chromatography-tandem mass spectrometric (LC-MS/MS) assay method for the simultaneous determination of saxagliptin and its active metabolite 5-hydroxy saxagliptin in human plasma. Th...
Comparative study on effects of nebulized and oral salbutamol on a cecal ligation and puncture-induced sepsis model in rats [0.03%]
比较雾化和口服沙丁胺醇对大鼠盲肠结扎穿孔诱导的脓毒症模型的影响：一项比较研究
B Ozogul,Z Halici,E Cadirci et al.
B Ozogul et al.
Aim: The present study aimed to compare the effects of different routes of salbutamol administration (oral and nebulized) at different doses in a cecal ligation and puncture-induced (CLP-induced) sepsis model of rats. ...
Comparative Study
Drug research. 2015 Apr;65(4):192-8. DOI:10.1055/s-0034-1375683 2015
Synthesis and evaluation of anti-acetylcholinesterase activity of some benzothiazole based new piperazine-dithiocarbamate derivatives [0.03%]
一些基于苯并噻唑的新哌嗪-二硫代氨基甲酸酯衍生物的合成及其乙酰胆碱酯酶活性评价
U A Mohsen,Z A Kaplancikli,Y Özkay et al.
U A Mohsen et al.
In this present study some benzothiazole derivatives bearing piperazine and thiocarbamate moieties were synthesized and their potential anticholinesterase properties were investigated. A set of 30 new compounds of 2-[(6-substituted benzothi...