Plumbagin Protects Against Spinal Cord Injury-induced Oxidative Stress and Inflammation in Wistar Rats through Nrf-2 Upregulation [0.03%]
通过Nrf-2上调抵御氧化应激和炎症的白刺素促进Wistar大鼠脊髓损伤恢复
W Zhang,L Cheng,Y Hou et al.
W Zhang et al.
Background: Spinal cord injury causes post-traumatic degeneration through series of biochemical events. This study aims to evaluate the possible protective mechanism of Plumbagin against Spinal cord injury induced oxidati...
Pharmacokinetics, Tissue Distribution and Plasma Protein Binding Studies of Rohitukine: A Potent Anti-hyperlipidemic Agent [0.03%]
罗侯蒂酮的药动学、组织分布和血浆蛋白结合研究：一种有效的抗高脂血症药物
Y S Chhonker,H Chandasana,A Kumar et al.
Y S Chhonker et al.
Rohitukine (RH) is a chromone alkaloid considered as one of the major active component of Dysoxylum binectariferum, exhibiting diverse pharmacological activities such as anti-hyperlipidemic, anti-cancer, anti-inflammatory, immuno-modulatory...
Antiatherosclerotic Potential of Rhizoma Polygonati Polysaccharide in Hyperlipidemia-induced Atherosclerotic Hamsters [0.03%]
Rhizoma Polygonati Polysacchar肽通过降低血脂和炎性因子抑制高脂血症模型仓鼠的动脉粥样硬化形成潜力
X Zhu,Q Li,F Lu et al.
X Zhu et al.
The present study aimed to investigate the antiatherosclerotic effect of rhizoma polygonati polysaccharide. Adult golden hamsters (Mesocricetus auratus) were fed an atherosclerotic diet containing 1.5 mL olive oil, 8 mg (320,000 IU) vitamin...
Isolation and phenotypic characterization of cancer stem like cells from nasopharyngeal carcinoma [0.03%]
鼻咽癌肿瘤干细胞的分离及其表型分析
Y Wang,G-H Zhang,S-L Li
Y Wang
Introduction: Recent studies reported that cancer stem cells (CSCs) are responsible for treatment failure and tumor recurrence. CSCs have been isolated and characterized in several solid tumors. However, the information r...
Comparative Evaluation of Intrathecal Bupivacaine Alone, Bupivacaine-fentanyl, and Bupivacaine-dexmedetomidine in Caesarean Section [0.03%]
单次腰麻布比卡因、布比卡因-芬太尼及布比卡因-右美托咪定用于剖宫产手术的比较研究
Y Sun,Y Xu,G-N Wang
Y Sun
Purpose: In this study, we aimed to compare the effects of bupivacaine alone, bupivacaine plus fentanyl, and bupivacaine plus dexmedetomidine for postoperative analgesia in women undergoing cesarean section under spinal a...
Randomized Controlled Trial
Drug research. 2015 Sep;65(9):468-72. DOI:10.1055/s-0034-1387740 2015
3,4,5-Trisubstituted Furan-2(5H)-one Derivatives: Efficient one-pot Synthesis and Evaluation of Cytotoxic Activity [0.03%]
3,4,5-三取代的呋喃-2(5H)-酮衍生物：有效的“一锅法”合成及细胞毒性评价
W M Basyouni,Kh A M El-Bayouki,A S El-Sayed et al.
W M Basyouni et al.
A series of 3,4,5-trisubstituted 2(5H)-furanone derivatives was synthesized through one-pot reaction of amines, aldehydes and diethyl acetylenedicarboxylate. Silica sulfuric acid efficiently catalyzes the 3-component reaction to afford the ...
M Aquib,A K Najmi,M Akhtar
M Aquib
Objective: The present study was carried out to determine the role of thymoquinone (TQ) in modulating the levels of neurotransmitter and reducing the oxidative stress in animal models of depression. ...
Synergistic antitumor effect of α-pinene and β-pinene with paclitaxel against non-small-cell lung carcinoma (NSCLC) [0.03%]
α-蒎烯和β-蒎烯与紫杉醇协同抑制非小细胞肺癌(NSCLC)的增殖和转移
Z Zhang,S Guo,X Liu et al.
Z Zhang et al.
The objective of the present research work was to evaluate the synergistic interactions between Paclitaxel (PAC) with α-pinene and β-pinene using isobolographic method against non-small-cell lung cancer cells (NSCLC). This type of interac...
The Effect of Long Term Pre/postnatal Low/high Dose Nicotine Exposure on Tissue Oxidant/antioxidant Status and DNA Damage in Rats [0.03%]
长期低剂量和高剂量尼古丁暴露对组织氧化/抗氧化状态及DNA损伤的影响
S Mizrak,V Turan,O Caglayan et al.
S Mizrak et al.
Background: Most women do not stop smoking either during pregnancy or in the lactation period. This study was carried out to investigate the effect of long term per oral pre/postnatal low/high dose nicotine exposure on fe...
Antitumor Efficacy of Docetaxel-loaded Nanocarrier against Esophageal Cancer Cell Bearing Mice Model [0.03%]
载多西他赛纳米载体抗食管癌细胞荷瘤小鼠模型肿瘤效果研究
Z-J Huang,N Yang,T-W Xu et al.
Z-J Huang et al.
Esophageal carcinoma is one of the most prevalent cancers with high rate of mortality worldwide. Intravenous and oral-based chemotherapeutic regimens were employed; however all the current treatment modalities are largely unsuccessful. Ther...