Curcumin in Type 2 Diabetes Mellitus: A Natural Approach to Modulating Metabolic Dysfunction [0.03%]
姜黄素在2型糖尿病中的作用：一种调节代谢紊乱的天然方法
Rufaida Wasim,Sumaiya Azmi,Mohammad Owais et al.
Rufaida Wasim et al.
A complex and multifaceted metabolic disease, type 2 diabetes mellitus (T2DM) is becoming a significant public health concern. Due to their many biological characteristics, bioactive compounds from herbal medicine have been shown in multipl...
Efficacy and Safety of Prolonged Treatment with Pemafibrate plus an HMG-CoA Reductase Inhibitor in Japanese Patients with Type 2 Diabetes Mellitus [0.03%]
在日本2型糖尿病患者中评估 pemafibrate 联合他汀类药物长期治疗的有效性和安全性
Masataka Kusunoki,Fumiya Hisano,Shin-Ichi Matsuda et al.
Masataka Kusunoki et al.
It has been suggested that caution should be exercised when using HMG-CoA reductase inhibitor (statin) in combination with a drug of the fibrate family because of the potentially elevated risk of development of hepatic function impairment a...
Bushra Imran,Farogh Ahsan,Tarique Mahmood et al.
Bushra Imran et al.
Canagliflozin is a synthetic sodium glucose transporter inhibitor (SGLT2i). It is the latest approved class of medicine used in the treatment of type 2 diabetes mellitus. As diabetes is emerging as the most common metabolic disorder, SGLT2i...
A Real-world Pharmacovigilance Study Of FDA Adverse Event Reporting System (FAERS) Events For Gender Of Voriconazole Drugs [0.03%]
氟康唑药品不良事件性别差异的真实世界药理学研究
Qiong Xu,Hongxia Cheng,Xu Sun et al.
Qiong Xu et al.
To detect the gender variations in adverse events (AEs) of voriconazole, promote personalised medicine.A normalized dataset from Q1 2004 to Q4 2022 from the US Food and Drug Administration's Adverse Event Reporting System (FAERS) was analys...
Protective Effects of Niclosamide Ethanolamine Against Testosterone-Induced Benign Prostatic Hyperplasia in Rats [0.03%]
尼卡巴嗪乙醇胺对雄激素诱导的良性前列腺增生大鼠的保护作用
Ali Hussein Jasim,Ahmed Rahmah Abu-Raghif,Zeena Ayad Hussein
Ali Hussein Jasim
Benign prostatic hyperplasia is a common urological condition in aging men. The anthelmintic agent niclosamide ethanolamide exhibits a wide range of pharmacological activities. This study aimed to evaluate the protective effect of niclosami...
Enhancing Doxorubicin Sensitivity in Osteosarcoma Cancer Cells: Unveiling the Role of Resveratrol-Induced Oxidative DNA Damage [0.03%]
白藜醇诱导的氧化DNA损伤在提高成骨肉瘤癌细胞对阿霉素敏感性中的作用
Mohammad Reza Bazavar,Hamed Helali,Linda Mohammadzadeh Boukani et al.
Mohammad Reza Bazavar et al.
Our current research aims to investigate how Resveratrol influences DOX-induced apoptosis in Saos-2 cells resulting from DNA damage.Saos-2 cells were cultured with DOX, and an MTT assay was conducted to evaluate cell viability. The expressi...
Asad Ahmad,Juber Akhtar,Mohammad Ahmad et al.
Asad Ahmad et al.
Both local and systemic medication delivery benefit greatly from the sublingual and buccal modes of administration. They have shown to be a successful substitute for the conventional oral route, particularly in situations requiring a quick ...
Design and Optimization of Novel Pyrimidine-Morpholine Hybrids Through Computational Approaches for SRC Kinase Inhibitory Activity [0.03%]
基于计算方法设计和优化SRC激酶抑制剂新型嘧啶-吗啉杂环化合物的研究与优化
Knolin K Thachil,V Soumya
Knolin K Thachil
Src (non receptor tyrosine kinase) plays a role in multiple pathways leading to tumor survival, proliferation and metastasis. Inhibiting Src kinase would be a therapeutic benefit in Src dependent cancers. Most of the nitrogen containing het...
A Randomized, Controlled Study Evaluating Effects of Saccharomyces boulardii in Adult Patients with Asthma [0.03%]
一项随机对照研究：评估酿酒酵母对哮喘成人患者的影响
Kavosh Ansari Dezfouli,Mahboubeh Darban,Maral Hemmati et al.
Kavosh Ansari Dezfouli et al.
To determine the potential benefit of adding Saccharomyces boulardii (S. boulardii) probiotic supplementation to conventional treatments in asthmatic patients.In this randomized, double-blinded, and placebo-controlled trial 50 asthmatic pat...
Therapeutic Potential of Sotagliflozin in Animal Models of Non-alcoholic Fatty Liver Disease with and without Diabetes [0.03%]
Sotagliflozin的治疗潜力：用于糖尿病和非糖尿病动物模型的非酒精性脂肪肝病的研究
Nitin J Deshmukh,M S Kalshetti,Mohan Patil et al.
Nitin J Deshmukh et al.
Sotagliflozin, a dual SGLT1/2 inhibitor, enhances glucagon like peptide-1 (GLP-1) levels and GLP-1 receptor agonists are used to manage non-alcoholic fatty liver disease (NAFLD). Study investigates the effects of sotagliflozin on NAFLD, alo...