Effect of Chronic Administration of Buspirone and Fluoxetine on Inflammatory Cytokines in 6-Hydroxydopamine-lesioned Rats [0.03%]
长效布斯吡龙和氟西丁对6-羟基多巴胺损伤大鼠炎症细胞因子的影响
H Sharifi,A M Nayebi,S Farajnia et al.
H Sharifi et al.
Neuro-inflammation in Parkinson's disease (PD) is associated with glial cell activation and production of different inflammatory cytokines. In this study we investigated the effect of chronic administration of buspirone and fluoxetine on ce...
Efficacy and Safety of Sufentanil and Pethidine in Spinal Anesthesia for Painless Labor [0.03%]
硫酸舒芬太尼与哌替啶用于无痛分娩腰麻镇痛效果及安全性分析
S Salarian,M Fathi,B Farzanegan et al.
S Salarian et al.
Saddle spinal is a reliable method for control of pain during labor. This method has rapid onset and causes complete sensory block without significant influence on motor neurons.Our goal was to compare the analgesic efficacy and side effect...
Randomized Controlled Trial
Drug research. 2015 Jul;65(7):344-6. DOI:10.1055/s-0034-1372610 2015
A simple HPLC method with fluorescence detection for simultaneous determination of 10-methoxycamptothecin and its metabolite 10-hydroxycamptothecin in rat liver tissue [0.03%]
一种简单的心脏组织和血浆中阿卡波糖的固相萃取-阳离子交换反向色谱法测定方法
Y Liu,C Shao,B Fan et al.
Y Liu et al.
A simple HPLC method to determine the amount of 10-methoxycamptothecin (MCPT) and its major metabolite 10-hydroxycamptothecin (HCPT) in rat liver tissue was developed in the present study. Camptothecin (CPT) was used as internal standard (I...
Validation and method development of Tadalafil in bulk and tablet dosage form by RP-HPLC [0.03%]
原料药和片剂制剂中西地那非的RP-HPLC验证及方法学研究
A Bojanapu,A T Subramaniam,J Munusamy et al.
A Bojanapu et al.
A novel, precise, rapid and sensitive reverse phase high performance liquid chromatographic method has been developed for the validated estimation of Tadalafil in bulk and tablet dosage form. The separation was achieved on Agilent Eclipse X...
Pharmacokinetics of metronidazole, tetracycline and bismuth in healthy volunteers after oral administration of compound tablets containing a combination of metronidazole, tetracycline hydrochloride and bismuth oxide [0.03%]
甲硝唑、盐酸四环素和氧化亚铅组成的一种复方片剂的健康志愿者生物利用度试验
Y Wu,L Ding,N-Y Huang et al.
Y Wu et al.
Background: To eradicate Helicobacter pylori in human pylorus and to heal duodenal ulcers, recently, a new formulation of combination tablets containing metronidazole 125 mg, tetracycline hydrochloride 125 mg and bismuth ...
Clinical Trial
Drug research. 2015 Feb;65(2):74-81. DOI:10.1055/s-0034-1372611 2015
C I N&#x;Da,A Petzer,J P Petzer
C I N&#x;Da
Purpose: A virtual screening study has suggested that the skeletal muscle relaxant, dantrolene, and the antiemetic drug, ondansetron, may act as inhibitors of the enzyme acetylcholinesterase (AChE). Based on this proposal...
Comparative Study
Drug research. 2015 Jan;65(1):46-51. DOI:10.1055/s-0034-1372612 2015
Pharmacokinetics and pharmacodynamics of two vitamin K1 formulations in rats [0.03%]
两种维生素K1制剂在大鼠体内的药代动力学和药效学研究
L Ma,Y Cao,L Chen et al.
L Ma et al.
Purpose: Severe allergic reactions associated with the commercially available formulation of vitamin K1 injection (VKI) could be a result of polysorbate that was added to solubilize vitamin K1 (VK1). Hence, we sought to d...
Effects of rolipram and zaprinast on learning and memory in the Morris water maze and radial arm maze tests in naive mice [0.03%]
Rolipram和Zaprinast对初尝试水迷宫和辐射型臂迷宫试验的学习和记忆的影响
F Akar,O Mutlu,I K Celikyurt et al.
F Akar et al.
Inhibition of phosphodiesterase 5 (PDE) improved recognition memory and counteracted spatial learning impairment induced by nitric oxide synthase (NOS) inhibition in recent studies. Aim of this study was to investigate effects of rolipram, ...
Hepatoprotective and antioxidant activities of Hepacare®, a herbal formulation against carbon tetrachloride-induced liver injury [0.03%]
Hepacare®(一种草药配方)对四氯化碳致肝损伤的 hepatoprotective 和抗氧化作用
I O Ishola,A A Akinyede,A K Robert et al.
I O Ishola et al.
Background: Hepacare(®) is a herbal formulation used to treat patients with sickle-cell anaemia complicated with jaundice, also recommended as a protective agent against liver damage due to chronic ingestion of alcohol. ...
Comparative Study
Drug research. 2015 Jan;65(1):30-9. DOI:10.1055/s-0034-1371829 2015
Hepatoprotective effect of Matricaria chamomilla.L in paraquat induced rat liver injury [0.03%]
罗马洋甘菊(Matricaria chamomilla L.)对百草枯致大鼠肝损伤的保护作用研究
H S Tavakol,K Farzad,M Fariba et al.
H S Tavakol et al.
Paraquat (PQ), an effective and widely used herbicide, has been proven to be safe when appropriately applied to eliminate weeds. However, PQ poisoning is an extremely frustrating clinical condition with a high mortality and with a lack of e...