Lisa Ruck,Susanna Wiegand,Peter Kühnen
Lisa Ruck
Background: Increasing prevalence of morbid obesity accompanied by comorbidities like type 2 diabetes mellitus (T2DM) led to a demand for improving therapeutic strategies and pharmacological intervention options. Apart fr...
B cell phenotype and serum levels of interferons, BAFF, and APRIL in multisystem inflammatory syndrome in children associated with COVID-19 (MIS-C) [0.03%]
与COVID-19相关的儿童多系统炎症综合征(MIS-C)的B细胞表型及干扰素、BAFF和APRIL的血清水平
Adam Klocperk,Marketa Bloomfield,Zuzana Parackova et al.
Adam Klocperk et al.
Background: Multisystem inflammatory syndrome in children associated with COVID-19 (MIS-C) is a late complication of pediatric COVID-19, which follows weeks after the original SARS-CoV-2 infection, regardless of its sever...
A novel serum calprotectin (MRP8/14) particle-enhanced immuno-turbidimetric assay (sCAL turbo) helps to differentiate systemic juvenile idiopathic arthritis from other diseases in routine clinical laboratory settings [0.03%]
一种新型的血清Cal保护蛋白(sCAL Turbo)颗粒增强免疫 turbidimetric 检测可帮助在常规临床实验室中将全身型幼年特发性关节炎与其他疾病区别开来
Dirk Foell,Melanie Saers,Carolin Park et al.
Dirk Foell et al.
Background: Differential diagnosis in children with signs of unprovoked inflammation can be challenging. In particular, differentiating systemic juvenile idiopathic arthritis (SJIA) from other diagnoses is difficult. We h...
What do we know about the sleep effects of caffeine used to treat apnoea of prematurity? A systematic review of the literature [0.03%]
咖啡因治疗早产儿呼吸暂停对睡眠的影响研究——文献综述
Ana Renata Pinto de Toledo,Higor Arruda Caetano,Jovito Adiel Skupien et al.
Ana Renata Pinto de Toledo et al.
Objective: Scientific scrutiny has proved the safety and benefits of caffeine to treat apnoea of prematurity (AOP). However, there is no consensus on the effects of this treatment on sleep, especially considering the key ...
Retinopathy of prematurity: from oxygen management to molecular manipulation [0.03%]
早产儿视网膜病变：从用氧管理到分子干预
Jonathan Woods,Susmito Biswas
Jonathan Woods
Introduction: Retinopathy of prematurity (ROP) is a vasoproliferative disorder of the premature retina with the potential to progress to extraretinal neovascularisation. This review serves as an introduction to retinopath...
Autoimmune lymphoproliferative immunodeficiencies (ALPID) in childhood: breakdown of immune homeostasis and immune dysregulation [0.03%]
儿童自身免疫性淋巴增生综合征（ALPS）：免疫稳态失调和免疫失调节
Vasil Toskov,Stephan Ehl
Vasil Toskov
Many inborn errors of immunity (IEI) manifest with hallmarks of both immunodeficiency and immune dysregulation due to uncontrolled immune responses and impaired immune homeostasis. A subgroup of these disorders frequently presents with auto...
Characterization of adolescents with functional respiratory disorders and prior history of SARS-CoV-2 [0.03%]
具有SARS-CoV-2既往史的青少年功能性呼吸系统疾病患者的临床特征分析
Sebastian Felix Nepomuk Bode,Anja Schwender,Monika Toth et al.
Sebastian Felix Nepomuk Bode et al.
Background: The SARS-CoV-2 pandemic has caused significant pulmonary morbidity and mortality in the adult population. Children and adolescents typically show milder symptoms; however, a relevant proportion of them report ...
Francesco Foppiano,Bianca Schaub
Francesco Foppiano
Background: Asthma is an inflammatory lung disease that constitutes the most common noncommunicable chronic disease in childhood. Childhood asthma shows large heterogeneity regarding onset of disease, symptoms, severity, ...
Sex differences in long-term kidney fibrosis following neonatal nephron loss during ongoing nephrogenesis [0.03%]
新生肾生成期间新生儿肾小球损失后的长期肾纤维化性别差异
Carlos Menendez-Castro,Nada Cordasic,Fabian B Fahlbusch et al.
Carlos Menendez-Castro et al.
Background: Clinical studies suggest that female sex plays a protective role in the development and progression of kidney disease. Recent experimental studies indicate that in male rats early nephron loss under ongoing ne...
Real-world evidence study on tolerance and growth in infants fed an infant formula with two human milk oligosaccharides vs mixed fed and exclusively breastfed infants [0.03%]
两种人乳低聚糖婴儿配方奶粉喂养婴幼儿的现实世界研究：对婴儿食物耐受性和生长发育的影响与混合喂养及纯母乳喂养婴儿进行对比
Frank Jochum,Martina Meyer-Krott,Tina Hübler et al.
Frank Jochum et al.
Introduction: Human milk oligosaccharides (HMOs) are important components of human milk having diverse functions in the development of infants. Randomized controlled trials (RCTs) have demonstrated that infant formulas wi...