The role of chitin, chitinases, and chitinase-like proteins in pediatric lung diseases [0.03%]
儿童肺部疾病中几丁质、几丁质酶及几丁质酶样蛋白的作用
Ines Mack,Andreas Hector,Marlene Ballbach et al.
Ines Mack et al.
Chitin, after cellulose, the second most abundant biopolymer on earth, is a key component of insects, fungi, and house-dust mites. Lower life forms are endowed with chitinases to defend themselves against chitin-bearing pathogens. Unexpecte...
Sophie Niedermaier,Anne Hilgendorff
Sophie Niedermaier
Neonatal chronic lung disease in the preterm infant, i.e. bronchopulmonary dysplasia (BPD) is characterized by impaired pulmonary development with its effects persisting into adulthood. Triggered in the immature lung by infectious complicat...
miRNA-221 is elevated in cystic fibrosis airway epithelial cells and regulates expression of ATF6 [0.03%]
MiRNA-221在囊性纤维化气道上皮细胞中升高并调节ATF6的表达
Irene K Oglesby,Raman Agrawal,Marcus A Mall et al.
Irene K Oglesby et al.
Background: MicroRNA (miRNA) and messenger RNA (mRNA) expression differs in cystic fibrosis (CF) versus non-CF bronchial epithelium. Here, the role of miRNA in basal regulation of the transcription factor ATF6 was investi...
Diagnostic delay in cerebral creatine deficiency disorders: lessons learned from a cross-sectional single center study, and guanidinoacetate and creatine measurements in Switzerland between 2015 and 2023 [0.03%]
脑磷脂缺陷障碍的诊断延迟：来自横断面单中心研究的经验教训以及2015年至2023年在瑞士测量的胍基乙酸和creatine的数据分析
Background: Cerebral creatine deficiency disorders (CCDD) are rare diseases caused by defects in the enzymes L-arginine: glycine amidinotransferase (AGAT) or guanidinoacetate-N-methyltransferase (GAMT), which are involved...