Intersectionality of early developmental risks and resilience after preterm birth [0.03%]
早产儿发育早期风险的交叉性及其韧性发展的相关因素
Julia Jäkel,Janika Ludwig,Britta Hüning et al.
Julia Jäkel et al.
The period from conception through preschool age represents a critical developmental window for both microbiome and brain. During this time, several modifiable factors may influence development via the gut-brain axis, including the mode of ...
Victoria Pradler,Clyde J Wright,Nazanin Kazemi-Butterfield et al.
Victoria Pradler et al.
Background: While advancements in neonatal intensive care have significantly improved the survival of preterm infants, inflammation-related complications continue to be a major factor in short- and long-term morbidity, es...
Sex differences in the long-term tolerability of BNT162b2 in children and adolescents [0.03%]
BNT162b2 mRNA新冠疫苗在青少年中的长期耐受性分析：性别差异的影响
Jeanne Moor,Vivien Grieshaber,Nicole Toepfner et al.
Jeanne Moor et al.
Background: Sex differences exist not only in the efficacy but also in adverse event rates of many vaccines. Here we compared the sex differences in the tolerability of BNT162b2 in children younger than 18 years in German...
Jianan Jie,Mengling Qiu,Xing Liu et al.
Jianan Jie et al.
Whole-exome sequencing identified a novel de novo heterozygous LEF1 variant (c.880 C > T; p.Pro294Ser) in a male pediatric patient who presented with intractable chronic yellow-green watery diarrhea with onset at 18 months of age. The condi...
Preventive application of lung growth factors and lack of attenuation of phenotype disruption of lung resident MSC from preterm infants by hyperoxia [0.03%]
预防性应用肺生长因子及早产儿肺部居民间充质干细胞不受高氧暴露影响而导致表型紊乱的研究
Lena Holzfurtner,Judith Behnke,Pauline Korte et al.
Lena Holzfurtner et al.
Background: Phenotype disruption of lung resident mesenchymal stem cells (MSC) is a key event in the pathogenesis of bronchopulmonary dysplasia (BPD). Hyperoxia (HOX) constitutes one major harmful factor resulting in grow...
In-hospital rotavirus vaccination in premature and medically ill infants: a systematic review of uptake and safety [0.03%]
早产和患病婴儿院内轮状病毒疫苗接种的系统评价：接受率及安全性
Janna-Lina Kerth,Calvin Kurz,Jonas Obitz et al.
Janna-Lina Kerth et al.
Background: Rotavirus vaccination is widely recommended in infancy and has substantially reduced morbidity from severe gastroenteritis. In premature and medically ill infants, prolonged hospitalization often interferes wi...
Caffeine citrate increases ciliary beat frequency in human respiratory epithelial cells [0.03%]
柠檬酸咖啡因可增加人体呼吸上皮细胞的纤毛摆动频率
Sandra Cindrić,Laura Bodenbeck,Rim Hjeij et al.
Sandra Cindrić et al.
Background: Caffeine citrate is the gold-standard pharmacological treatment for apnea of prematurity, improving survival and long-term respiratory outcomes in preterm infants. Beyond its established central nervous system...
Real-world impact of nirsevimab on RSV hospitalizations in children under 2 years of age: retrospective monocentric study in a large German tertiary pedatric center [0.03%]
nirsevimab对2岁以下儿童RSV住院的现实世界影响：德国大型三级儿科中心的回顾性单中心研究
Moritz Bauer,Anke Wendt,Marcus A Mall et al.
Moritz Bauer et al.
Background: Respiratory syncytial virus (RSV) infection is a leading cause of hospitalization among infants and young children. Broad immunization with the monoclonal antibody nirsevimab represents a promising preventive ...
Phenocopies of 22q11.2DS: revealing genetic diversity in clinically suspected 22q11.2 deletion syndrome [0.03%]
22q11.2DS的表型拷贝：揭示临床疑似22q11.2缺失综合征中的遗传多样性
Fanni Szumutku,Anna Lengyel,Éva Pinti et al.
Fanni Szumutku et al.
Background: Although 22q11.2 deletion syndrome (22q11.2DS) is one of the most common microdeletion syndromes, a substantial proportion of patients with clinically suspected 22q11.2DS (clin22q11.2) remain without a definit...
Current skin care practices in very low birth weight infants in German Neonatal Intensive Care Units - results from a cross-sectional survey [0.03%]
德国NICU极低出生体重儿的当前皮肤护理实践——一项横断面调查结果
Janina Marissen,Regina Thoma,Christoph Härtel
Janina Marissen
Background: The skin is the largest epithelial organ and a critical barrier. However, in preterm infants, particularly very low birth weight infants (VLBWI, < 1500 g), it is immature and highly susceptible to injury and i...