Perinatal origins of chronic lung disease: mechanisms-prevention-therapy-sphingolipid metabolism and the genetic and perinatal origins of childhood asthma [0.03%]
儿童慢性肺疾病的围生期起源：机制-预防-治疗-鞘脂代谢与儿童哮喘的遗传和围生期起源
Emily Wasserman,Stefan Worgall
Emily Wasserman
Childhood asthma derives from complex host-environment interactions occurring in the perinatal and infant period, a critical time for lung development. Sphingolipids are bioactive molecules consistently implicated in the pathogenesis of chi...
Mitali Sahni,Vineet Bhandari
Mitali Sahni
Bronchopulmonary dysplasia (BPD) continues to be one of the most common complications of prematurity, despite significant advancement in neonatology over the last couple of decades. The new BPD is characterized histopathologically by impair...
Translational research approaches to study pediatric polycystic kidney disease [0.03%]
研究儿童多囊肾的转化医学方法
Max Christoph Liebau,Djalila Mekahli
Max Christoph Liebau
Polycystic kidney diseases (PKD) are severe forms of genetic kidney disorders. The two main types of PKD are autosomal recessive and autosomal dominant PKD (ARPKD, ADPKD). While ARPKD typically is a disorder of early childhood, patients wit...
Imaging of peripheral vascular malformations - current concepts and future perspectives [0.03%]
周围血管畸形的影像学检查-现状及未来展望
Vanessa F Schmidt,Max Masthoff,Michael Czihal et al.
Vanessa F Schmidt et al.
Vascular Malformations belong to the spectrum of orphan diseases and can involve all segments of the vascular tree: arteries, capillaries, and veins, and similarly the lymphatic vasculature. The classification according to the International...
Agnes Hackl,Seif El Din Abo Zed,Paul Diefenhardt et al.
Agnes Hackl et al.
Idiopathic nephrotic syndrome (INS) in children is characterized by massive proteinuria and hypoalbuminemia and usually responds well to steroids. However, relapses are frequent, which can require multi-drug therapy with deleterious long-te...
Does allogeneic stem cell transplantation in survivors of pediatric leukemia impact regular physical activity, pulmonary function, and exercise capacity? [0.03%]
同种异体造血干细胞移植对儿童白血病幸存者的常规体育活动、肺功能和运动能力有影响吗？
Katharina Ruf,Alaa Badran,Céline Siauw et al.
Katharina Ruf et al.
Background: Allogeneic hematopoietic stem cell transplantation (allo-HSCT) has improved survival in high-risk childhood leukemia but is associated with long-term sequelae such as impaired pulmonary function and reduced ex...
Bacterial metabolites and cardiovascular risk in children with chronic kidney disease [0.03%]
慢性肾脏疾病儿童的细菌代谢产物和心血管风险
Julia Schlender,Felix Behrens,Victoria McParland et al.
Julia Schlender et al.
Cardiovascular complications are the major cause of the marked morbidity and mortality associated with chronic kidney disease (CKD). The classical cardiovascular risk factors such as diabetes and hypertension undoubtedly play a role in the ...
Exome sequencing implicates a novel heterozygous missense variant in DSTYK in autosomal dominant lower urinary tract dysfunction and mild hereditary spastic paraparesis [0.03%]
外显子测序暗示DSTYK基因新型杂合错义变异可能导致常染色体显性遗传下尿路功能障碍和轻度遗传性痉挛性双侧脊髓病
Clara Vidic,Marcin Zaniew,Szymon Jurga et al.
Clara Vidic et al.
Introduction: DSTYK encodes dual serine/threonine and tyrosine protein kinase. DSTYK has been associated with autosomal-dominant congenital anomalies of the kidney and urinary tract and with autosomal-recessive hereditary...
Correction to: Novel ways to monitor immunosuppression in pediatric kidney transplant recipients-underlying concepts and emerging data [0.03%]
校正：监测儿科肾移植受者免疫抑制的新方法-潜在概念和新兴数据
Thurid Ahlenstiel-Grunow,Lars Pape
Thurid Ahlenstiel-Grunow
Published Erratum
Molecular and cellular pediatrics. 2021 Sep 30;8(1):14. DOI:10.1186/s40348-021-00124-w 2021