Francesco Foppiano,Bianca Schaub
Francesco Foppiano
Background: Asthma is an inflammatory lung disease that constitutes the most common noncommunicable chronic disease in childhood. Childhood asthma shows large heterogeneity regarding onset of disease, symptoms, severity, ...
Sex differences in long-term kidney fibrosis following neonatal nephron loss during ongoing nephrogenesis [0.03%]
新生肾生成期间新生儿肾小球损失后的长期肾纤维化性别差异
Carlos Menendez-Castro,Nada Cordasic,Fabian B Fahlbusch et al.
Carlos Menendez-Castro et al.
Background: Clinical studies suggest that female sex plays a protective role in the development and progression of kidney disease. Recent experimental studies indicate that in male rats early nephron loss under ongoing ne...
Real-world evidence study on tolerance and growth in infants fed an infant formula with two human milk oligosaccharides vs mixed fed and exclusively breastfed infants [0.03%]
两种人乳低聚糖婴儿配方奶粉喂养婴幼儿的现实世界研究:对婴儿食物耐受性和生长发育的影响与混合喂养及纯母乳喂养婴儿进行对比
Frank Jochum,Martina Meyer-Krott,Tina Hübler et al.
Frank Jochum et al.
Introduction: Human milk oligosaccharides (HMOs) are important components of human milk having diverse functions in the development of infants. Randomized controlled trials (RCTs) have demonstrated that infant formulas wi...
Markos K Tomidis Chatzimanouil,Ines Goppelt,Yvonne Zeissig et al.
Markos K Tomidis Chatzimanouil et al.
Metamizole is an analgesic, antipyretic, and spasmolytic drug in Germany only approved for the treatment of severe pain or high fever that does not respond to other measures. In recent years, an increased use has been described among both a...
Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus (jSLE) [0.03%]
儿童期起病的系统性红斑狼疮(SLE)神经系统损害临床分析
Valentina Natoli,Amandine Charras,Gabriele Hahn et al.
Valentina Natoli et al.
Systemic lupus erythematosus (SLE) is a rare autoimmune/inflammatory disease with significant morbidity and mortality. Approximately 15-20% of SLE patients develop the disease during childhood or adolescence (juvenile-onset SLE/jSLE). Patie...
Perinatal origins of bronchopulmonary dysplasia-deciphering normal and impaired lung development cell by cell [0.03%]
肺发育细胞生物学:正常与异常的肺发育的单细胞解析及支气管肺发育不良的起源
I Mižíková,B Thébaud
I Mižíková
Bronchopulmonary dysplasia (BPD) is a multifactorial disease occurring as a consequence of premature birth, as well as antenatal and postnatal injury to the developing lung. BPD morbidity and severity depend on a complex interplay between p...
New insights into the immune functions of podocytes: the role of complement [0.03%]
足细胞免疫功能的新见解:补体的作用
Valentina Bruno,Anne Katrin Mühlig,Jun Oh et al.
Valentina Bruno et al.
Podocytes are differentiated epithelial cells which play an essential role to ensure a normal function of the glomerular filtration barrier (GFB). In addition to their adhesive properties in maintaining the integrity of the filtration barri...
Caroline M Kolvenbach,Gabriel C Dworschak,Johanna M Rieke et al.
Caroline M Kolvenbach et al.
Advances in molecular biology are improving our understanding of the genetic causes underlying human congenital lower urinary tract (i.e., bladder and urethral) malformations. This has recently led to the identification of the first disease...
Katarzyna Gendera,Stanimir Georgiev,Peter Ewert et al.
Katarzyna Gendera et al.
Catheterization of the umbilical vessels has proven to be an effective and relatively rapid method for gaining central vascular access in neonates. However, it can be technically difficult, the procedure may last 30 min or longer, and it ca...
Non-invasive pediatric cardiac imaging-current status and further perspectives [0.03%]
非创伤性儿科心脏影像学 - 现状与展望
Meinrad Beer,Björn Schönnagel,Jochen Herrmann et al.
Meinrad Beer et al.
Background: Non-invasive cardiac imaging has a growing role in diagnosis, differential diagnosis, therapy planning, and follow-up in children and adolescents with congenital and acquired cardiac diseases. This review is b...