Licensed Subcutaneous Infusion Therapies in Advanced Parkinson's Disease: An Indirect Treatment Comparison and Cost-Minimisation Analysis [0.03%]
晚期帕金森病的 licensed subcutaneous infusion 治疗:间接治疗比较和成本最小化分析
Marc Vérin,Ángel Sesar,Bharat Amlani et al.
Marc Vérin et al.
Introduction: Parkinson's disease is the second most common neurodegenerative disorder. In advanced Parkinson's disease, subcutaneous (SC) infusion therapies represent minimally invasive and reversible treatment options. ...
Early Intervention and Speed-to-Effect in Spinal Muscular Atrophy Type 1 Following Onasemnogene Abeparvovec Gene Replacement Therapy: Results of aPost-Hoc Analysis of Pooled Clinical Study Data [0.03%]
针对脊髓性肌萎缩症1型患者在onasemnogene abeparvovec基因替代治疗后的早期干预和快速起效:临床研究合并数据分析的事后分析结果
Walter Toro,Sandra P Reyna,Shannon Ritter et al.
Walter Toro et al.
Introduction: Studies suggest that early intervention with disease-modifying treatment for spinal muscular atrophy (SMA) might provide the best opportunity for optimal outcomes. One such treatment is onasemnogene abeparvo...
The Predictive Value of Heart Rate Variability for the Prognosis of Patients with Mild to Moderate Traumatic Brain Injury [0.03%]
心率变异性对中重度创伤性脑损伤患者预后的预测价值
Chenyu Wu,Lu Liu,Du Chen et al.
Chenyu Wu et al.
Introduction: Traumatic brain injury (TBI) is a major cause of death and disability in adults. After the injury, patients may experience autonomic dysfunction of the heart, making heart rate variability (HRV) an important...
Summary of Research: Blood Biomarker Dynamics in People with Relapsing Multiple Sclerosis Treated with Cladribine Tablets: Results of the 2-Year MAGNIFY-MS Study [0.03%]
克拉屈滨片治疗复发性多发性硬化症患者的研究综述:MAGNIFY-MS研究两年结果摘要
Heinz Wiendl,Frederik Barkhof,Xavier Montalban et al.
Heinz Wiendl et al.
Cladribine tablets (CladT) for relapsing multiple sclerosis help reset the immune system with short treatment courses over 2 years. This analysis of MAGNIFY-MS contrasted clinical outcomes with changes in immune cells, proteins and genes ov...
Societal Costs and Efficiency of Subcutaneous versus Intravenous Lecanemab in Early Alzheimer's Disease: A U.S. Cost Comparison Model [0.03%]
早期阿尔茨海默病患者皮下注射和静脉注射莱卡奈单抗的社会成本与效率:美国成本比较模型
Amir Abbas Tahami Monfared,Stephanie Barrows,Lindsey Fox et al.
Amir Abbas Tahami Monfared et al.
Introduction: Intravenous (IV) therapies often impose significant burdens and costs on payers, providers, patients, and caregivers. A fixed-dose subcutaneous (SC) formulation may enhance convenience, improve outcomes, and...
Early Introduction of Cenobamate in Uncontrolled Focal Epilepsy: Insights from a Structured Controversy [0.03%]
早期使用Cenobamate治疗难治性局灶性癫痫:来自结构化争议的见解
Angelo Labate,Claudio Liguori,Elena Tartara et al.
Angelo Labate et al.
Introduction: Drug-resistant focal epilepsy, as defined by the International League Against Epilepsy (ILAE), is characterized by the failure to achieve seizure control despite the use of at least two appropriately chosen ...
Case Report: Acute Psychiatric Behavioral Disturbance in a Patient with Presenilin 1 Gene Mutation Associated with Familial Alzheimer's Disease [0.03%]
病例报告:与家族性阿尔茨海默病相关的早老素基因突变患者的急性精神行为障碍
Yong Xia,Xiaoyan Liu,Wenjing Cui et al.
Yong Xia et al.
Familial Alzheimer's disease (FAD), often linked to presenilin 1 (PSEN1) mutations, is characterized by an autosomal dominant inheritance and earlier onset compared to sporadic Alzheimer's disease. We report a 48-year-old female patient dia...
Correction: Are Glucagon-Like Peptide‑1 (GLP-1) Receptor Agonists Central Nervous System (CNS) Penetrant: A Narrative Review [0.03%]
纠正:胰高血糖素样肽-1(GLP-1)受体激动剂是中枢神经系统(CNS)穿透剂吗:叙述性综述
Juliana West,Maggie Li,Sabrina Wong et al.
Juliana West et al.
Published Erratum
Neurology and therapy. 2025 Jun 25. DOI:10.1007/s40120-025-00758-2 2025
From Headache to Heart Health: Investigating the Migraine-Cardiovascular Disease Connection [0.03%]
从头痛到心脏健康:探究偏头痛与心血管疾病之间的联系
Claudio Tana,Dilara Onan,Roberta Messina et al.
Claudio Tana et al.
Migraine, particularly with aura, has been consistently associated with an increased risk of cardiovascular disease, including ischemic stroke and myocardial infarction. Shared pathophysiological mechanisms such as endothelial dysfunction, ...
Impact of Early Antipsychotic Prescription Choice on Weight Gain in the First 5 Years of Psychotic Illness: a Retrospective Cohort Study [0.03%]
抗精神病药初选对前五年精神病体重增加的影响:一项回顾性队列研究
Adrian Heald,George Tilston,John Julian Warner-Levy et al.
Adrian Heald et al.
Introduction: We analysed the effects of antipsychotic drug prescribing in year 1 of treatment for psychosis on future weight gain over 5 years. Methods: ...