Assessing the Safety and Efficacy of Lamotrigine as Anti-myotonic Agent in Myotonic Dystrophy Type 1 (DM1): A Longitudinal, Open-Label, Pilot Study [0.03%]
拉莫三嗪治疗1型肌强直性营养不良的疗效及安全性：一项纵向、开放标记的试点研究
Barbara Risi,Nesaiba Ait Allali,Stefano Cotti Piccinelli et al.
Barbara Risi et al.
Introduction: Myotonia, defined as impaired relaxation of skeletal muscles after voluntary contraction or electrical stimulation, is a core feature of myotonic dystrophy type 1 (DM1) and can be highly disabling. The most ...
Sequential use of OnabotulinumtoxinA and Erenumab in Chronic Migraine: Retrospective Real-World Report on Bidirectional Switching [0.03%]
慢性 migraine患者使用OnabotulinumtoxinA和Erenumab顺序治疗：双向转换的回顾性、真实世界报告
Carolin Luisa Hoehne,Aysenur Sahin,Lucas Hendrik Overeem et al.
Carolin Luisa Hoehne et al.
Introduction: In clinical practice, switching between preventive treatments is common in patients with chronic migraine when efficacy is insufficient or tolerability is poor. With the advent of more targeted therapies, su...
Clinical Performance of the Elecsys CSF pTau181/Aβ42 Ratio for Concordance with Tau-PET in Two Independent Cohorts [0.03%]
采用两个独立队列对Elecsys脑脊液pTau181/Aβ42比值检测与tau-PET的一致性研究
Ruben Smith,Leslie Shaw,Sebastian Palmqvist et al.
Ruben Smith et al.
Introduction: Amyloid- and tau-positron emission tomography (PET) are promising modalities for detecting pathological changes associated with Alzheimer's disease (AD); however, their application is limited. Although the u...
Update on the Present and Future Pharmacologic Treatment of Parkinson's Disease [0.03%]
帕金森病当前和未来药物治疗的现状及展望
Thomas Müller
Thomas Müller
Symptomatic drug treatment of Parkinson's disease combines various pharmacological principles for a patient-tailored drug combination. Development of more continuous delivery modes of dopamine-substituting drugs with formulations with bette...
Cristina Gonzalez-Robles,Oliver Bandmann,Anthony H V Schapira
Cristina Gonzalez-Robles
Parkinson disease (PD) is a progressive neurodegenerative condition characterised by tremor, bradykinesia and rigidity, as well as other motor and non-motor symptoms, for which no effective disease-modifying treatments have been discovered....
Incidence and Risk Factors for Serious Infections in Patients with Neuromyelitis Optica Spectrum Disorder: A Claims Database Study in Japan [0.03%]
日本神经脊髓炎谱系障碍患者严重感染的发病率及危险因素：基于理赔数据库的一项研究
Noriko Isobe,Tetsuro Oda,Tomohiro Yamaguchi et al.
Noriko Isobe et al.
Introduction: Serious infection is a leading cause of mortality in patients with neuromyelitis optica spectrum disorder (NMOSD). We assessed the incidence of and risk factors for serious infections in patients with NMOSD....
Characteristics of Postural Instability in Idiopathic Normal Pressure Hydrocephalus [0.03%]
特发性正常压力脑积水姿势不稳的特征
Eunhee Park,Kyunghun Kang,Janghoon Lee et al.
Eunhee Park et al.
Introduction: In patients with idiopathic normal pressure hydrocephalus (iNPH), the characteristics of static steady-state balance disturbance are not as well understood as those related to gait. This study aimed to inves...
Five-Year Safety and Efficacy Outcomes with Ofatumumab in Patients with Relapsing Multiple Sclerosis [0.03%]
奥法木单抗治疗复发性多发性硬化症患者的5年安全性和有效性结果
Stephen L Hauser,Jeffrey A Cohen,Jérôme de Sèze et al.
Stephen L Hauser et al.
Introduction: Ofatumumab demonstrated superior efficacy and similar safety versus teriflunomide in ASCLEPIOS I/II in people with relapsing multiple sclerosis; no new safety concerns and sustained efficacy were observed up...
Retrospective Multicenter Chart Review Study of Adjunctive Cannabidiol for Seizures Associated with Lennox-Gastaut Syndrome, Dravet Syndrome and Tuberous Sclerosis Complex [0.03%]
列觉-加斯托综合征、德拉维特综合征和结节性硬化症相关性癫痫的辅助大麻二酚治疗：多中心病历回顾研究
Adam Strzelczyk,Kerstin Alexandra Klotz,Thomas Mayer et al.
Adam Strzelczyk et al.
Introduction: Effectiveness and tolerability of plant-derived highly purified cannabidiol (CBD) in patients with Lennox-Gastaut syndrome (LGS), Dravet syndrome (DS), or tuberous sclerosis complex (TSC)-associated epilepsy...
Correction: Levodopa Intestinal Gel Infusion Therapies in Advanced Parkinson's Disease: A Swedish Study on Real-World Use and Costs [0.03%]
纠正： advanced parkinson 疾病患者的左旋多巴肠凝胶输注疗法：一项瑞典真实世界使用和成本研究
Per Odin,Christoffer Tærud,Jenny Samuelsson et al.
Per Odin et al.
Published Erratum
Neurology and therapy. 2025 Jul 10. DOI:10.1007/s40120-025-00797-9 2025