Characterizing the Journey of Early Alzheimer's Disease in Patients Initiating Lecanemab Treatment in the United States: A Real-World Evidence Study [0.03%]
美国开始乐卡莫单抗治疗的阿尔茨海默病患者早期疾病的现实世界证据研究
Marwan N Sabbagh,Chenyue Zhao,Malena Mahendran et al.
Marwan N Sabbagh et al.
Introduction: With the advent of disease-modifying therapies for early Alzheimer's disease (AD), a comprehensive characterization of patients initiating lecanemab in the USA is needed to understand its use in real-world s...
Efficacy of Stiripentol Beyond Dravet Syndrome: A Retrospective Medical Record Review of Patients with Drug-Resistant Epilepsies [0.03%]
司替戊醇应用于难治性癫痫疗效观察：德拉韦综合征之外的拓展经验（回顾性研究）
Víctor Soto-Insuga,Elena González-Alguacil,María Ballarà-Petitbò et al.
Víctor Soto-Insuga et al.
Introduction: Stiripentol is approved as an add-on therapy with clobazam and/or valproate for seizures associated with Dravet syndrome (DS). Evidence of stiripentol efficacy in other drug-resistant epilepsies is limited. ...
Incidence and Prevalence of Juvenile Myasthenia Gravis in the United States Between 2010 and 2020: Analysis of Two Claims Databases [0.03%]
2010年至2020年美国重症肌无力的患病率和发病率：两个理赔数据库分析
Jiachen Zhou,Anna Kuba,Sigrid Nilius et al.
Jiachen Zhou et al.
Introduction: Few published population-based studies report the incidence or prevalence of juvenile myasthenia gravis (JMG) due to the rarity of the disorder. Despite recent progress in new targeted treatments and ongoing...
SMA Community Priorities for Future Drug Therapies: Cross-Sectional Survey Findings Representing 410 Adults with SMA [0.03%]
脊髓性肌萎缩症(SMA)患者社区对未来药物治疗的优先项：针对410名SMA患者的横断面调查结果
Ilse S Peterson,Ramaa Chitale,Mary A Curry et al.
Ilse S Peterson et al.
Introduction: Despite advances in the therapeutic landscape for spinal muscular atrophy (SMA), unmet needs for those with this condition persist. This study seeks to characterize unmet needs that adults with SMA hope futu...
Patient Experience of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP): A Qualitative Exploration of Signs, Symptoms, and Health-Related Quality of Life Impacts [0.03%]
慢性炎症性脱髓鞘多发神经病（CIDP）患者的体验：关于体征、症状和健康相关生活质量影响的定性探索
Anna Roberts,Natasha Griffiths,Kieran Thiara et al.
Anna Roberts et al.
Introduction: Chronic inflammatory demyelinating polyneuropathy (CIDP) is a rare type of autoimmune neuropathy, characterized by signs of distal and proximal weakness of the upper and lower limbs, sensory dysfunction, abs...
High-Dose Steroids, Treatment Escalation, and Healthcare Burden in Myasthenia Gravis: A US Claims-Based Cohort Study [0.03%]
高剂量皮质类固醇、治疗升级和重症肌无力的医疗负担：基于美国理赔资料队列研究
Mar Pujades-Rodríguez,Adam Jedrzejczyk,Jiachen Zhou et al.
Mar Pujades-Rodríguez et al.
Introduction: Myasthenia gravis (MG) is a rare neuromuscular autoimmune disease, characterized by chronic, fluctuating muscle weakness and fatigability. Despite established therapies, many patients have inadequately contr...
Safety Monitoring of Omaveloxolone in Friedreich Ataxia: Results from One Year of Clinical Treatment [0.03%]
奥马iveloxolone治疗弗里德reich共济失调的安全性监测：一年临床治疗的结果分析
Katherine Gunther,Victoria Profeta,Medina Keita et al.
Katherine Gunther et al.
Introduction: Omaveloxolone, the only approved medication for Friedreich ataxia (FRDA), is an NRF2 activator available since July 2023. We examined safety monitoring of omaveloxolone administration over the first 12 month...
Comparison of Factors Affecting Quality of Life in Patients with Acute Ischemic Stroke Across Different Stroke Severities [0.03%]
不同卒中严重程度的急性缺血性卒中患者生活质量影响因素比较分析
Yuxuan Lu,Weiping Sun,Yining Huang et al.
Yuxuan Lu et al.
Introduction: Research investigating the differences in determinants affecting the quality of life (QoL) in patients with acute ischemic stroke (AIS) of varying severities remains limited, and how these factors influence ...
Cost-Effectiveness of Newborn Screening for Spinal Muscular Atrophy in Australian Hospitals [0.03%]
澳大利亚医院进行脊髓性肌萎缩症新生儿筛查的成本效益分析
Ian R Woodcock,Didu S Kariyawasam,Maina P Kava et al.
Ian R Woodcock et al.
Introduction: This analysis evaluated the cost-effectiveness of newborn screening (NBS) for spinal muscular atrophy (SMA) from the perspective of Australian state hospital payers. ...
Burnout Among Physicians Treating Patients with Multiple Sclerosis in the United States: A Podcast [0.03%]
美国治疗多发性硬化症患者的医师的职业倦怠感：一期播客节目
Mary Rensel,Amy B Sullivan
Mary Rensel
Physician burnout, a growing crisis in the healthcare system of the United States of America (USA), is characterized by long-term job-related stress that manifests as energy depletion, feelings of increased mental distance from or cynicism ...