Optimizing Clinical Indicators in Hematologic Malignancies and Sepsis Using ddPCR: A Retrospective Study [0.03%]
采用ddPCR优化血液系统恶性肿瘤和脓毒症的临床指标：回顾性研究
Bei Zheng,Chuanwei Xin,Yizhuo Liu et al.
Bei Zheng et al.
Introduction: Early antibacterial treatment is critical for patients with hematologic malignancies (HMs) and sepsis. Droplet digital polymerase chain reaction (ddPCR) can rapidly detect pathogens and antimicrobial resista...
Effective Management of Carbapenem-Resistant Enterobacterales Bloodstream Infection with Organ Dissemination in Prolonged Severe Agranulocytosis Patients with Hematological Malignancy Through Combination Therapies Including Eravacycline [0.03%]
通过包括艾拉 cycline 的联合治疗有效管理血液系统恶性肿瘤患者在严重粒细胞缺乏症持续期间发生碳青霉烯耐药肠杆菌科 BSI 并累及器官病例的研究
Yuyuan Lv,Xin Zhang,Qingya Cui et al.
Yuyuan Lv et al.
This study reports three patients with hematologic malignancy patients and Carbapenem-resistant Enterobacterales (CRE) bloodstream infections and organ dissemination during neutropenia. After failed conventional therapy, a novel "through Co...
Cost-Effectiveness Analysis of Influenza Treatments in Japan Using a Transmission Model: The Impact of Baloxavir and Oseltamivir Shares [0.03%]
日本流感治疗的成本效益分析：利用传播模型评估巴洛沙韦和奥司他韦使用比例的影响
Ataru Igarashi,Takahiro Takazono,Naoki Hosogaya et al.
Ataru Igarashi et al.
Introduction: Influenza is a highly transmissible respiratory viral infection, with a risk of severe complications and excess respiratory mortality. Clinical trial data showed that baloxavir was more effective than oselta...
Hepatocellular Carcinoma Recurrence in Patients with Chronic Hepatitis C Infection Treated with Direct-Acting Antivirals: A Systematic Review and Meta-Analysis [0.03%]
直接抗病毒药物治疗慢性丙型肝炎感染患者的肝细胞癌复发：系统评价和meta分析
Kristina Lindsley,Margaret Burroughs,Candido Hernandez-Lopez et al.
Kristina Lindsley et al.
Introduction: Reports of direct-acting antivirals (DAA) use for chronic hepatitis C virus (HCV) infection after successful treatment of hepatocellular carcinoma (HCC) have suggested higher rates of HCC recurrence. However...
Effectiveness of a Single Dose of Pneumococcal Conjugate Vaccine Against Invasive Pneumococcal Disease in Children: A Systematic Literature Review [0.03%]
儿童单剂量肺炎球菌结合疫苗对侵袭性肺炎链球菌疾病的保护效果：系统文献回顾
Eileen M Dunne,Linge Hong,Benjamin M Althouse et al.
Eileen M Dunne et al.
Introduction: While pneumococcal conjugate vaccines (PCVs) are typically administered to infants using a three- or four-dose regimen, children may receive less immunogenic regimens due to missed doses or alternative sched...
A Cost-Effectiveness Analysis of the Switch to 20-Valent Pneumococcal Conjugate Vaccine from Lower-Valent Pneumococcal Conjugate Vaccines in the French Pediatric Population [0.03%]
法国儿科人群中从低价肺炎球菌结合疫苗转换至20价肺炎球菌结合疫苗的成本效益分析
Stéphane Fiévez,An Ta,Lucile Bellier et al.
Stéphane Fiévez et al.
Introduction: The pneumococcal conjugate vaccine (PCV) with valency of 20 (PCV20) was approved for pediatric use by the European Commission in 2024. However, PCV20 is not yet implemented into the French infant National Im...
Safety and Efficacy of Fecal Microbiota, Live-jslm to Prevent Recurrent Clostridioides difficile Infection in Participants With Irritable Bowel Syndrome [0.03%]
粪便微生物活菌制剂预防伴有肠易激综合征的复发性艰难梭状芽胞杆菌感染的安全性和疗效
Olga C Aroniadis,Beth Guthmueller,Kaitlin Dehlin et al.
Olga C Aroniadis et al.
Introduction: The safety and efficacy of microbiota-based products in patients with irritable bowel syndrome (IBS) and recurrent Clostridioides difficile infection (rCDI) has not been studied. Fecal microbiota, live-jslm ...
Comparison of Effectiveness between Ceftazidime/Avibactam and Other Active Therapies for Oxacillinase-48-Producing Carbapenem-Resistant Klebsiella pneumoniae Bacteremia in Taiwan [0.03%]
台湾产氧氟沙星酶48型耐碳青霉烯类肺炎克雷伯菌血流感染对头孢他啶/阿维巴坦与其它活性药物的反应比较研究
Szu-Yu Liu,Chien Chuang,Chih-Han Juan et al.
Szu-Yu Liu et al.
Introduction: Oxacillinase-48 (OXA-48)-producing carbapenem-resistant Klebsiella pneumoniae (CRKP) infections have been increasingly reported in Taiwan. Real-world studies regarding effective treatments for these infectio...
A Cohort Study of Pediatric Severe Community-Acquired Pneumonia Involving AI-Based CT Image Parameters and Electronic Health Record Data [0.03%]
基于人工智能的CT影像参数和电子健康档案数据的儿童重症社区获得性肺炎队列研究
Mengyuan He,Jianpeng Yuan,Aijiao Liu et al.
Mengyuan He et al.
Introduction: Community-acquired pneumonia (CAP) is a significant concern for children worldwide and is associated with a high morbidity and mortality. To improve patient outcomes, early intervention and accurate diagnosi...
Can We Lower the Burden of Antimicrobial Resistance (AMR) in Heavily Immunocompromised Patients? A Narrative Review and Call to Action [0.03%]
如何降低抗菌药物耐药性（AMR）在重度免疫抑制患者中的负担？叙述性综述与行动呼吁
Matteo Bassetti,Antonella Cardone,Fatima Cardoso et al.
Matteo Bassetti et al.
Effective antibiotics are a cornerstone of treatment for heavily immunocompromised patients such as those undergoing cancer treatment or transplantation procedures, as these patients are at particularly high risk of adverse outcomes from in...