Real-World Effectiveness of Ceftazidime-Avibactam for Multidrug-Resistant Gram-Negative Pneumonia, Time-Stratified Risk Factors for Short- and Long-Term Mortality, and Inpatient Costs: A Multicenter Retrospective Cohort Study [0.03%]
头孢他啶-阿维巴坦治疗多重耐药革兰阴杆菌肺炎的真实世界有效性、分层分析短期和长期病死率的时间依赖性危险因素及住院费用:多中心回顾性队列研究
Chao Liu,Wei Li,Enjing Zhang et al.
Chao Liu et al.
Introduction: Multidrug-resistant (MDR) Gram-negative pneumonia is associated with high mortality and substantial healthcare resource utilization. Ceftazidime-avibactam (CAZ-AVI) is an important option, yet real-world exp...
Broadening the Assessment of Antimicrobial Value: Insights from Two Evaluations of Aztreonam-Avibactam in Spain [0.03%]
抗菌药物价值评估的拓展——基于西班牙两种评价看aztreonam-avibactam的价值
Sonia Luque,Luis Martínez-Martínez,Ricard Ferrer et al.
Sonia Luque et al.
Early Warning and Behavioural Intervention on the Cardiovascular Disease Risk in People Living with HIV: A Multicentre Non-Randomized Controlled Trial [0.03%]
针对艾滋病病毒感染者心血管疾病风险的早期预警及行为干预研究:一项多中心非随机对照试验
Yuyin Zhou,Chunhui Yan,Zhonghua Xia et al.
Yuyin Zhou et al.
Introduction: Human Immunodeficiency Virus (HIV) infection has currently become a manageable chronic disease with the prevalence of antiretroviral therapy (ART). The increase in life expectancy and the rising number of pe...
Immunogenicity, Tolerability, and Safety of BA.1-Adapted BNT162b2 Vaccine in 18- to 55-Year-Olds Previously Vaccinated with BNT162b2 or Who Were COVID-19 Vaccine-Naive [0.03%]
先前接种过BNT162b2疫苗或未接种过新冠肺炎疫苗的18至55岁成人接种改良型omicron BA.1 针对性BNT162b2疫苗的免疫原性、耐受性和安全性
David Fitz-Patrick,Omair Sahgal,Leon F Fouché et al.
David Fitz-Patrick et al.
Introduction: Variant-adapted COVID-19 vaccines can induce more robust immune responses against closely matched circulating variants than original vaccines. ...
Cost-Effectiveness of Bivalent Respiratory Syncytial Virus Prefusion F Vaccine for Older Adults in the Netherlands [0.03%]
荷兰老年人二价呼吸道合胞病毒前融合F疫苗的成本效益分析
Annefleur C Langedijk,Floris van den Dungen,Frits M E Franssen et al.
Annefleur C Langedijk et al.
Introduction: Lower respiratory tract disease caused by respiratory syncytial virus (RSV-LRTD) is associated with substantial clinical and economic burden among older adults and adults with chronic medical conditions. Biv...
The Impact of Influenza on Health-Related Quality of Life, Work Productivity, and Activity Impairment Among Symptomatic US Patients with Influenza [0.03%]
流感对美国流感患者的健康相关生活质量、工作效率和活动能力的影响
Tianyan Hu,Laura L Lupton,Alon Yehoshua et al.
Tianyan Hu et al.
Introduction: Evidence on the impact of influenza on health-related quality of life (HRQoL) and work productivity and activity impairment (WPAI) remains limited. This study evaluated changes in the EuroQol Visual Analogue...
Impact of Switching from Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide or Entecavir in Older Patients with Chronic Hepatitis B [0.03%]
替诺福韦酯换用替诺福韦艾拉酚胺或恩替卡韦治疗老年慢性乙型肝炎患者的疗效及安全性:一项随机、开放标签的非劣效性试验
Federico Cesanelli,Ottavia Nozza,Federica Gottardi et al.
Federico Cesanelli et al.
Introduction: Tenofovir disoproxil fumarate (TDF) is highly effective for chronic hepatitis B (CHB) but may induce progressive renal impairment and proximal tubular dysfunction. Switching to tenofovir alafenamide (TAF) or...
Global Viral Lower Respiratory Disease Episodes, Hospitalisations, and Clinical Outcomes by Aetiology, 2010-2021 [0.03%]
2010至2021年全球病毒性下呼吸道疾病发病、住院及病因临床结局分析
Ekaterina Maslova,Quinn Rafferty,Jiali Lei et al.
Ekaterina Maslova et al.
Introduction: Viral lower respiratory tract disease (LRTD) is a major cause of global morbidity and mortality, but pathogen-specific estimates remain limited. We aimed to quantify the global burden of viral LRTD episodes,...
Streptococcal Pharyngitis in Paediatric Primary Care: Clinical Characteristics, Recurrences, Complications, and Antibiotic Management [0.03%]
儿科门诊儿童化脓性咽炎的临床特点、复发、并发症及抗生素治疗特征分析
Nicolo Monti,Giovanni Vitali Rosati,Federica Ravidà et al.
Nicolo Monti et al.
Introduction: Group A streptococcal (GAS) pharyngitis is the most common bacterial infection in childhood. National and international guidelines consistently recommend narrow-spectrum beta-lactams as first-line therapy; h...
Hospitalisation Burden of Human Metapneumovirus and Respiratory Syncytial Virus in Adults by Age and Comorbidity Status in Scotland: A Retrospective Analysis [0.03%]
苏格兰成人住院患者的人类副流感病毒和呼吸道合胞病毒的负担:按年龄和合并症状况进行的回顾性分析
Durga Kulkarni,Richard Osei-Yeboah,Kate Templeton et al.
Durga Kulkarni et al.
Introduction: Respiratory syncytial virus (RSV) is well recognised as an important contributor to respiratory tract infections (RTIs) in adults in Scotland. However, there is a lack of recognition of the role of human met...