Ultrathin Nanofibers Ameliorate Commercial Gauze for Rapid Hemorrhage Control Via Improved Clotting Kinetics and Rbc Modulation [0.03%]
超薄纳米纤维通过改善凝血动力学和红细胞调节来优化商用纱布以实现快速止血控制
Shivangi Parhi,Ashmita Mukherjee,Pratik Das et al.
Shivangi Parhi et al.
Timely control of bleeding is crucial to reduce mortality in traumatic injuries, highlighting the urgent need for biomaterials with anti-hemorrhagic properties. Polycaprolactone (PCL) is commonly used for producing nanofibers in the range o...
Yuhan Wang,Chen Gao,Shengnan Cheng et al.
Yuhan Wang et al.
Conductive hydrogels are highly attractive in 3D bioprinting of tissue engineered scaffolds for skin injury repair. However, their application is limited by mismatched electrical signal conduction mode and poor printability. Herein, the 3D ...
Engineering Iridium Nanoclusters for Boosting Ferroptotic Cell Death by Regulating GPX4 and p53 Functions [0.03%]
工程化铱纳米团簇通过调节GPX4和p53的功能来促进铁死亡细胞死亡
Xiaoyu Cui,Bin Chen,Ying Chen et al.
Xiaoyu Cui et al.
Emerging evidence indicates that modulating glutathione peroxidase 4 (GPX4) to induce ferroptosis is a promising strategy for tumor treatment. However, most of the GPX4 small molecule inhibitors face limitations due to their poor delivery e...
Self-Doped and Biodegradable Glycosaminoglycan-PEDOT Conductive Hydrogels Facilitate Electrical Pacing of iPSC-Derived Cardiomyocytes [0.03%]
自掺杂且可生物降解的甘氨酸氨基葡聚糖-PEDOT导电水凝胶促进诱导多能干细胞衍生的心肌细胞的电信号起搏
Daniel Hachim,Olivia Hernández-Cruz,James E J Foote et al.
Daniel Hachim et al.
Conductive polymers hold promise in biomedical applications owing to their distinct conductivity characteristics and unique properties. However, incorporating these polymers into biomaterials poses challenges related to mechanical performan...
Disrupting Biofilms on Human Kidney Stones-A Path Toward Reducing Infectious Complications During Stone Surgery [0.03%]
干扰人体肾结石上的生物膜 – 减少结石手术过程中感染并发症的一条路径
Daniel Massana Roquero,Grace H Holton,T Jessie Ge et al.
Daniel Massana Roquero et al.
Kidney stones are a common disorder associated with significant morbidity and often requires surgical intervention. Pathogenic bacteria are found in almost 40% of stones, where they form biofilms that are protected from systemic antibiotic ...
Flexible Short Silica Fibers and Tricalcium Phosphate Synergistically Promote Bone Fracture Healing in Composite Cryogel Scaffolds [0.03%]
柔性短硅纤维和三钙磷酸盐在复合冷冻凝胶支架中协同促进骨折愈合
Xinyi Wang,Zhengchao Yuan,Guangfang Cai et al.
Xinyi Wang et al.
Bone tissue engineering is a critical area of research focused on enhancing the regeneration of bone tissue, particularly in cases of complex defects. Despite inherent self-healing capabilities of bone, irregularly-shaped defects pose signi...
Living Microalgae-Based Magnetic Microrobots for Calcium Overload and Photodynamic Synergetic Cancer Therapy [0.03%]
基于活微藻的磁控微机器人用于光动力协同治疗癌症和钙超载
Shuai Jiang,Bo Hao,Xin Song et al.
Shuai Jiang et al.
The combination of Ca2+ overload and reactive oxygen species (ROS) production for cancer therapy offers a superior solution to the lack of specificity in traditional antitumor strategies. However, current therapeutic platforms for this stra...
Cerium-Containing Mesoporous Bioactive Glass Nanoparticles Reinforced 3D-Printed Bioceramic Scaffolds toward Enhanced Mechanical, Antioxidant, and Osteogenic Activities for Bone Regeneration [0.03%]
含铈介孔生物活性玻璃纳米粒子强化的3D打印生物陶瓷支架，用于提高机械性能、抗氧化和成骨活性以促进骨骼再生
Zihan Zhao,Xueying Chen,Heming Chen et al.
Zihan Zhao et al.
The repair of critical-sized bone defects remains a substantial clinical challenge. While 3D printing of bioceramics has emerged as a promising strategy to address this issue, conventional bioceramics often exhibit limited antioxidant and o...
Hollow-Structured Nanorobot with Excellent Magnetic Propulsion for Catalytic Pollutant Degradation, Anti-Bacterial and Biofilm Removal [0.03%]
用于催化污染物降解、抗菌和生物膜去除的具有优良磁推进性的中空结构纳米机器人
Jing Wang,Guangjin Yu,Qunling Fang et al.
Jing Wang et al.
Chemical pollution, pathogenic bacteria, and bacterial biofilms pose significant threats to public health. Although various nanoplatforms with both catalytic and antibacterial activities have been developed, creating a remotely controllable...