An Enhanced Long-Term Wet Adhesion Strategy of Spatial Control the Emergence of Dual Covalent Cross-Linking for Sutureless Cornea Transplant [0.03%]
通过空间控制双共价交联的出现以增强长期湿粘附力实现无缝线角膜移植的新策略
Zhuhao Tan,Wenfang Liu,Siqi Jiang et al.
Zhuhao Tan et al.
Corneal transplantation regeneration requires bioadhesives to perform long-term and stable adhesion functions in a wet environment. However, many current studies focus on the instantaneous or short-term adhesion persistence of bioadhesives,...
Bimetallic NiCu-MOF Protects DOX-Induced Myocardial Injury and Cardiac Dysfunction by Suppressing Ferroptosis and Inflammation [0.03%]
双金属NiCu-MOF通过抑制铁死亡和炎症来保护DOX诱导的心肌损伤和心脏功能障碍
Lu Liu,Daiyong Chao,Qing Dong et al.
Lu Liu et al.
Doxorubicin (DOX), a potent anthracycline chemotherapeutic agent, is widely used in cancer treatment but is associated with significant adverse effects, particularly DOX-induced cardiomyopathy (DIC). DIC pathogenesis involves the generation...
Smart Health Monitoring: Review of Electrochemical Biosensors for Cortisol Monitoring [0.03%]
智能健康监测：皮质醇监测电化学生物传感器综述
Zhijie Li,Dan Luo,Yaqian Zhang et al.
Zhijie Li et al.
Cortisol, also known as the stress hormone, is a crucial corticosteroid hormone that significantly increases secretion in the human body when facing notable stress. Monitoring cortisol levels is crucial for personal stress management and th...
Near-Infrared Imaging Agent ABSi-148 Alleviates CA IX-Mediated Hypoxic Fibrosis in Inflammation-Cancer Transition [0.03%]
近红外成像剂ABSi-148缓解炎症癌症过渡过程中CA IX介导的缺氧纤维化
Zhi Cao,Jingmin Li,Weibin Hu et al.
Zhi Cao et al.
Pancreatic ductal adenocarcinoma (PDAC) remains a formidable challenge due to its late diagnosis and intrinsic treatment resistance, exacerbates by its development from chronic inflammation to cancer transition (ICT). Here, this investigati...
Dual Functionalized Absorbable Hairy Cellulose-Based Fabric for Efficient Hemostasis and Antibacterial Property [0.03%]
具有止血和抗菌性能的双功能化可吸收羟基纤维素基织物
Nastaran Alipour,Seyedhosein Jarolmasjed,Salar Salmanipour et al.
Nastaran Alipour et al.
Uncontrolled hemorrhage and subsequent infection at the injury sites are major causes of trauma-related mortality. Herein, we present a novel approach to creating a multifunctional biodegradable textile fabric with hemostatic and antibacter...
Enhanced Immune Modulation and Bone Tissue Regeneration through an Intelligent Magnetic Scaffold Targeting Macrophage Mitochondria [0.03%]
通过智能磁性支架靶向巨噬细胞线粒体增强免疫调节和骨组织再生
Zuyun Yan,Tianshi Sun,Jin Zeng et al.
Zuyun Yan et al.
During the bone tissue repair process, the highly dynamic interactions between the host and materials hinder precise, stable, and sustained immune modulation. Regulating the immune response based on potential mechanisms of macrophage phenot...
3D-printed Engineered Trachea Functionalized by Diverse Extracellular Matrix Particles [0.03%]
通过多种细胞外基质颗粒功能化的3D打印工程气管
Weikang Lin,Hai Tang,Runfeng Cao et al.
Weikang Lin et al.
It remains a significant challenge to construct a tracheal substitute with both a native-like structure and multiple essential physiological functions. In this study, a combination of 3D printing techniques and a modular strategy is employe...
4D printed Stimuli Responsive Scaffold with Tissue Expansion and Photothermal Tumor Ablation Property for Post-Mastectomy Breast Reconstruction [0.03%]
具有组织扩张性和光热肿瘤消融性的刺激响应支架的4D打印在乳房再造中的应用
Muran Zhou,Guo Zhang,Jinfei Hou et al.
Muran Zhou et al.
Breast tissue engineering is a promising alternative to post-mastectomy breast reconstruction. However, the high relapse rate (about 20%) of this malignant tumor negatively affects its long-term prognosis. Moreover, the shortage of recipien...
Lycium-Barbarum Polysaccharide-Loaded Dual-Crosslinked Rigid Hydrogel Enhances Bone Healing in Diabetic Bone Defects by Scavenging Reactive Oxygen Species [0.03%]
载Lycium Barbarum多糖双重交联的 rigid 水凝胶通过清除氧自由基促进糖尿病骨缺损修复
Wenjie Zhong,Wenao Liao,Lingcong Xu et al.
Wenjie Zhong et al.
Diabetes-induced oxidative stress can lead to poor bone defect healing, severely affecting the quality of life for patients. Studies show that improving the microenvironment and promoting bone formation can effectively accelerate the healin...
Biofunctionalization of ADA-GEL Hydrogels Based on the Degree of Cross-Linking and Polymer Concentration Improves Angiogenesis [0.03%]
基于交联度和聚合物浓度的ADA-GEL水凝胶生物功能化改善了血管生成
Stefanie Heltmann-Meyer,Rainer Detsch,Jonas Hazur et al.
Stefanie Heltmann-Meyer et al.
The creation of bioartificial tissues is a promising option for the reconstruction of large-volume defects. The vascularization of tissue engineering constructs, as well as the material properties of the carrier matrix, are important factor...