Soft Pneumatic Device Designed to Mimic the Periosteal Environment for Regulating the Fate of Mesenchymal Stem Cells [0.03%]
用于调控间充质干细胞命运的仿骨膜环境软体气动装置设计
Gwang-Bum Im,Jae Gyeong Lee,Hosub Lim et al.
Gwang-Bum Im et al.
Replicating the complex mechanical forces of muscle movement and fluid flow in in vitro cell culture systems is crucial for understanding cell differentiation and development. However, previous research focused on cell differentiation on st...
Prodigiosin Loaded SN-PB@PG NPs-Based Multimodal Therapy for the Healing of Bacterial Infected Chronic Wounds [0.03%]
基于产芽孢载负能多 modal 疗法治疗细菌感染的慢性伤口
Zhou Wu,Li Chang,Changling Li et al.
Zhou Wu et al.
Healing of infected chronic wounds faces dual challenges: persistent inflammation and impaired angiogenesis. To address these, SN-PB@PG nanocomplexes were prepared by hybridisation of nitroprusside (SNP) with Prussian blue (SN-PB NPs) and l...
Francesca Pagliari,Maria-Francesca Spadea,Pierre Montay-Gruel et al.
Francesca Pagliari et al.
Radiotherapy (RT) is a cancer treatment technique that involves exposing cells to ionizing radiation, including X-rays, electrons, or protons. RT offers promise to treat cancer, however, some inherent limitations can hamper its performance....
Heng Zhao,Christian Serre,Nathalie Steunou
Heng Zhao
Inflammation is a natural immune response triggered by harmful external or internal stimuli. However, when inflammation fails to resolve and restore basal homeostasis, it can lead to various inflammatory diseases such as rheumatoid arthriti...
Research Progress on Antibacterial Applications of Bioactive Materials in Wound Infections: Design, Challenges, and Prospects [0.03%]
活性伤口感染抗菌材料的研究进展：设计、挑战和前景
Wang Zheng,Yuanfang Cheng,Hui Shen et al.
Wang Zheng et al.
Bacterial wound infections pose a significant threat to global health, exacerbated by the increase in multidrug-resistant bacteria (MDRB) and the formation of elastic biofilms. This review explores the transformative potential of bioactive ...
Biomimetic Co-delivery of Lenvatinib and FePt Nanoparticles for Enhanced Ferroptosis/Apoptosis Treatment of Hepatocellular Carcinoma [0.03%]
用于肝细胞癌治疗的仿生共输送 lenvatinib 和 FePt 纳米粒子以增强铁死亡/凋亡效果
Feichao Xuan,Xingyang Zhao,Weiran Pang et al.
Feichao Xuan et al.
Lenvatinib, endorse as a first-line targeted therapy, has demonstrated efficacy in extending the survival span of individuals afflicted with advanced Hepatocellular carcinoma (HCC). However, its therapeutic effect wears off with time, which...
Intrinsically Pro-Apoptotic Gold Nanoclusters for Optical Tracing and Inhibition of Solid Tumors [0.03%]
具有内在促凋亡作用的金纳米团簇用于实体瘤的光学追踪与抑制
Priyanka Sharma,Hao Yuan,Ruchi Verma et al.
Priyanka Sharma et al.
Intrinsically theranostic metal nanoclusters are rare unless the stabilizing ligands exhibit therapeutic properties. A promising class of quasi-molecular, near-infrared (NIR) emitting, cytotoxic gold nanoclusters, coined as AXE (Au eXcitabl...
Supercritical Fluid-Processed Multifunctional Hybrid Decellularized Extracellular Matrix with Chitosan Hydrogel for Improving Photoaged Dermis Microenvironment [0.03%]
超临界流体处理的多功能水凝胶/脱细胞基质复合材料对光老化皮肤微环境的改善作用
Seol-Ha Jeong,Jae Jun Kang,Ki-Myo Kim et al.
Seol-Ha Jeong et al.
To address the demand for reconstructive procedures in extensive subcutaneous tissue defects and significant dermis matrix loss, vascularized adipose tissue regeneration is essential for maintaining volume after material degradation. Accord...
A Novel pH-Responsive Baicalein@Chitosan Hydrogel for the Topical Treatment of Herpes Simplex Virus Type 1 Skin Infections: Therapeutic Potential and Mechanisms [0.03%]
用于单纯疱疹病毒1型皮肤感染局部治疗的新型pH响应式黄芩素@壳聚糖水凝胶：治疗潜力和机制
Yuhui Lu,Liying Zhou,Alu Ouyang et al.
Yuhui Lu et al.
Herpes simplex virus type 1 (HSV-1) is a prevalent human pathogen primarily transmitted through skin-to-skin contact. Traditional antiviral drugs like acyclovir (ACV) have limitations due to viral resistance and side effects, necessitating ...
An Expandable Brain-Machine Interface Enabled by Origami Materials and Structures for Tracking Epileptic Traveling Waves [0.03%]
由折纸材料和结构支持的可扩展脑机接口在追踪癫痫行进波中的应用
Tiancheng Sheng,Jingwei Li,Lingyi Zheng et al.
Tiancheng Sheng et al.
Tracking neural activities across multiple brain regions remains a daunting challenge due to the non-negligible skull injuries during implantations of large-area electrocorticography (ECoG) grids and the limited spatial accessibility of con...