MXene and Near-Infrared Carbon Dots Co-Encapsulated Hydrogel Facilitates Infected Bone Defect Reconstruction [0.03%]
负载MXene和近红外碳点的水凝胶用于感染骨缺损修复
Longfei Xiao,Yang Wang,Jinming Cai et al.
Longfei Xiao et al.
Inadequate bone differentiation and intractable biofilm formation due to stubborn bacterial infection complicate infected bone defect repair. Adding harmful antibiotics into scaffolds not only promotes multidrug-resistant bacteria but also ...
New NIR-Activated Organic Molecule-Based Nanocomposite as an Efficient Sensitizer for Photothermal and Photodynamic Therapy of Cancer [0.03%]
一种新型近红外激活有机分子基纳米复合材料用于癌症光热和光动力治疗的高效敏化剂
Ming-Hsin Liu,Zhen-Jie Gao,Wei-Yung Huang et al.
Ming-Hsin Liu et al.
Acceptor-donor-acceptor (A-D-A)-configured molecules with coplanar dithieno[2,3-d:2',3'-d']thieno[3,2-b:3',2'-b']dipyrrole (DTPT) as the core are promising organic semiconductor materials utilized in organic photovoltaic devices owing to th...
Younghak Cho,Yunyoung Choi,Yerim Jang et al.
Younghak Cho et al.
Biosensors serve as indispensable analytical tools in biomedical diagnostics, environmental monitoring, and personalized healthcare, offering operation simplicity, cost-effectiveness, high sensitivity, and portability. Nanostructure integra...
Neutrophil Membrane-Encapsulated Polymerized Salicylic Acid Nanoparticles Effectively Alleviating Rheumatoid Arthritis by Facilitating Sustained Release of Salicylic Acid into the Articular Cavity from Chondrocytes [0.03%]
通过促进软骨细胞向关节腔持续释放水杨酸，中性粒膜包被的聚化水杨酸纳米颗粒能有效缓解风湿性关节炎
Luying Yang,Feng Cao,Jiayu Lu et al.
Luying Yang et al.
Rheumatoid arthritis (RA) is a systemic autoimmune disease that primarily instigates chronic inflammation in multiple joints. Salicylic acid (SA) is a classic anti-inflammatory agent for the treatment of RA. To enhance the therapeutic effec...
Justin C Burrell,Zarina S Ali,Eric L Zager et al.
Justin C Burrell et al.
Peripheral nerve injury is a significant clinical challenge, often leading to permanent functional deficits. Standard interventions, such as autologous nerve grafts or distal nerve transfers, require sacrificing healthy nerve tissue and typ...
Molecular Modeling Studies of Hapten Design and Antibody Recognition for Sensitive Detection of Vitamin K3 by Strip Biosensor [0.03%]
用于维生素K3检测的抗原设计及抗体识别的分子模型研究
Jialin Hu,Xinxin Xu,Liqiang Liu et al.
Jialin Hu et al.
Computer-aided molecular design techniques are used to analyze vitamin K3 (VK3) and VK3-hapten. Based on VK3-hapten, a specific monoclonal antibody (mAb) against VK3 is prepared with a sensitivity (IC50) of 0.49 ng mL-1. The recombinant tec...
Lighting up Resistance: Rapid Antimicrobial Susceptibility Testing of Gram-Negative Bacteria in Bloodstream Infections Using an Aggregation-Induced Emission Bioprobe [0.03%]
发光检测耐药性：利用聚集诱导发射生物探针快速检测血液感染中革兰氏阴性菌的抗微生物耐药性
Xiaoxue Ge,Meng Gao,Nannan Cao et al.
Xiaoxue Ge et al.
Rapid and accurate antimicrobial susceptibility testing (AST) is crucial for guiding treatment and combating resistance. However, conventional ASTs are time-consuming and require pure colonies, delaying the initiation of targeted antimicrob...
Tumor-Targeted Exosome-Based Heavy Atom-Free Nanosensitizers With Long-Lived Excited States for Safe and Effective Sono-Photodynamic Therapy of Solid Tumors [0.03%]
具有长寿命激发态的肿瘤靶向基于外泌体的无重金属纳米增敏剂，用于实体瘤的安全有效的声动力光动力治疗
Van-Nghia Nguyen,Thuy Giang Nguyen Cao,Hyunsun Jeong et al.
Van-Nghia Nguyen et al.
Theranostic nanosensitizers with combined near-infrared (NIR) fluorescence imaging and sono-photodynamic effects have great potential for use in the personalized treatment of deep-seated tumors. However, developing effective nanosensitizers...
Dual-Mode Radiosensitization of Esophageal Squamous Cell Carcinoma via SOCS6-Loaded Virus-Inspired Manganese-Bismuth Bimetallic Oxide Nanoparticles [0.03%]
通过SOCS6负载的病毒灵感锰-铋双金属氧化纳米颗粒对食管鳞状细胞癌进行双重模式放疗增敏
Rui Ma,Zhi Yang,Xia Miao et al.
Rui Ma et al.
Radioresistance poses a significant obstacle to controlling the recurrence of esophageal squamous cell carcinoma (ESCC) during radiotherapy. It is urgent to develop innovative radiosensitization strategies to improve the prognosis of patien...
Leveraging the Shape Fidelity of 3D Printed Bone Scaffolds Through Architectural Tailoring of an Emulsion Ink: A Combined Experimental and Computational Analysis [0.03%]
通过乳液墨水的结构优化提高3D打印骨支架的形状保真度：实验与计算分析相结合的方法
Sagnik Ghosh,Shubham Shankar Mohol,Anupama Datta et al.
Sagnik Ghosh et al.
Hierarchical porous, bioactive, and biocompatible scaffolds with customizable multi-functionality are promising alternatives for autografts and allografts in bone tissue engineering. Combining high internal phase emulsion (HIPE) templating ...