Controlled Magnesium Ion Delivery via Mg-Sputtered Nerve Conduit for Enhancing Peripheral Nerve Regeneration [0.03%]
控制镁离子递送以促进周围神经再生的镁溅射神经导管的研究
Hyewon Kim,Jieun Kwon,Hyeok Kim et al.
Hyewon Kim et al.
Autologous nerve grafting remains the gold standard for treating peripheral nerve injuries; however, it is constrained by limited donor nerve availability, the need for secondary surgeries, and sensory loss at the donor site. Biodegradable ...
The Treatment of Large Bone Defects with Atrophic Nonunion by Bioactive Scaffolds Remodeling the Regeneration Microenvironment [0.03%]
生物活性支架重塑再生微环境治疗萎缩性大段骨不连
Zhuo Liang,Fei Xue,Jingdi Zhang et al.
Zhuo Liang et al.
Atrophic nonunion, a particularly challenging complication of diaphyseal bone fractures, arises from a deteriorated regenerative microenvironment characterized by insufficient vascularization and pathological accumulation of reactive oxygen...
Degradable Alginate Hydrogel Intervention Catheters with Gradient Hardness in Length [0.03%]
长度硬度呈梯度分布的可降解海藻酸盐水凝胶介入导管
Bingbing Yang,Weinan Gu,Jie Pan et al.
Bingbing Yang et al.
Interventional catheter, a medical device characterized by a gradient hardness from one end to the other, exhibits enhanced flexibility upon insertion into the human body. This unique configuration accommodates various anatomical structures...
Molybdenum Disulfide Nanocomposites for Cancer Diagnosis and Therapeutics: Biosensors, Bioimaging, and Phototherapy [0.03%]
用于癌症诊断和治疗的二硫化钼纳米复合材料：生物传感器、生物成像和光动力疗法
Fatemeh Sasanipoor,Zhiqing Zhang
Fatemeh Sasanipoor
Molybdenum disulfide (MoS₂) nanomaterials have attracted significant interest in cancer diagnosis and therapy due to their unique physicochemical properties. Due to its extensive surface area and adaptable structure, MoS₂ may engage with ...
A Self-Assembled Nanoreactor for Realizing Antibacterial Photodynamic/Gas Therapy and Promoting Wound Healing [0.03%]
一种用于实现抗菌光动力/气体疗法和促进伤口愈合的纳米反应器自组装方法
Chenyang Jia,Ling-Yi Li,Qiu-Yi Duan et al.
Chenyang Jia et al.
Among various treatments employed to solve the global problem of bacterial infection, photodynamic therapy (PDT) is recognized as a method with great potential to inactivate a wide range of bacteria without the development of drug resistanc...
Defect-Rich MoO3-X@CuO2 Nanosheets Mediated Ultrasound-Enhanced Cuproptosis Antibacterial Activity and M2 Macrophage Reprogramming for Optimizing Diabetic Wound Repairment [0.03%]
缺陷丰富的MoO3-X@CuO2纳米片介导的超声增强杯铂抗菌活性和M2巨噬细胞重编程以优化糖尿病伤口修复
Yutang Li,Yi Wang,Yandong Wang et al.
Yutang Li et al.
Diabetic wounds are often plagued by persistent bacterial infections, which exacerbate inflammation and impair healing processes such as collagen deposition and fibroblast migration. Conventional antibiotic therapies frequently prove ineffe...
Influence of Hypoxia on a Biomaterial Model of the Bone Marrow Perivascular Niche [0.03%]
缺氧对骨髓血管周围生态位生物材料模型的影响
Gunnar B Thompson,Victoria R Barnhouse,Sydney K Bierman et al.
Gunnar B Thompson et al.
Hematopoietic stem cell (HSC) fate is shaped by distinct microenvironments termed niches within the bone marrow. Quiescence, expansion, and differentiation are directly and indirectly regulated by complex combinations of cell secretomes, ce...
Qianmin Gao,Jian Wang,Hao Zhang et al.
Qianmin Gao et al.
Organoids provide 3D structures that replicate native tissues in biomedical research. The development of vascular networks within organoids enables oxygen and nutrient delivery while facilitating metabolic waste removal, which supports orga...
Ultrasound Trigger Ultrasmall Multifunction Nanobubbles for Thrombus Visual Treatment [0.03%]
用于血栓可视化治疗的超声触发多功能纳米气泡
Zijun Ma,Jiawei Wang,Maochun Zhang et al.
Zijun Ma et al.
Intravenous injection of thrombolytic drugs is the prevailing strategy for the treatment of thrombotic disease. However, its applications are limited due to hemorrhagic risk and thrombus microenvironment. In pursuit of visualized thrombolys...
Biofabrication of Spatially Organized Temporo-mandibular Fibrocartilage Assembloids [0.03%]
具有空间组织的颞下颌纤维软骨组装体的生物制造
Alexandre Dufour,Lucie Essayan,Beomjoon Kim et al.
Alexandre Dufour et al.
The combination of mesenchymal stem cell (MSC) spheroids and polymeric scaffolds has been actively explored for engineering organized hyaline cartilage; however, its application to other types of cartilage remains under-explored. The tempor...