Dynamic Mechanical Stimulation of Thermoresponsive Nanofibers for Activation of Fibroblasts in Skin Repair [0.03%]
动态机械刺激热响应纳米纤维以激活皮肤修复中的成纤维细胞
Xuran Guo,Ying Gao,Jiajia Yu et al.
Xuran Guo et al.
Substrate stiffness regulates fibroblast phenotype through focal adhesion-mediated mechanotransduction pathways to facilitate tissue repair and regeneration. To analyze the effects of dynamic mechanical stimulation of substrates on cell beh...
3D Bioprinting of Prevascularized Bone Organoids for Rapid In Situ Cranial Bone Reconstruction [0.03%]
用于快速原位颅骨重建的预血管化骨胚体的3D生物打印
Jing Duan,Yongcong Fang,Yueming Tian et al.
Jing Duan et al.
Despite rapid advances in the field of bone tissue engineering, cranial bone defects of critical size remain difficult to repair due to the limited self-regeneration capacity of the bone. Developmental engineering with mesenchymal stem cell...
Modeling Idiopathic Inflammatory Myopathy in the Bioinspired Muscle Tissue on Chip [0.03%]
基于生物启发的芯片上肌肉组织 modeling 干燥综合症炎症性肌病
Xu Zhang,Mengqian Zhao,Pengwei Deng et al.
Xu Zhang et al.
Idiopathic inflammatory myopathy (IIM) is an autoimmune disease that characterized by non-purulent inflammation of the skeletal muscle. However, due to the limitation of study model that can recapitulate the complex pathological process of ...
Xin Liu,Yevhen Fatieiev,Niveen M Khashab
Xin Liu
Supramolecular porous materials have been used to tackle some major challenges in modern biomedical science, including disease therapy and diagnosis. Their inherent dynamicity, stimuli-responsiveness, and tunable architectures enable precis...
Cascade Regulation of Blood Clot Stabilization-Cell Migration-Osteogenic Differentiation by Hollow Hydrogels for Periodontal Bone Regeneration and Repair [0.03%]
用于牙周骨再生和修复的空心水凝胶血液凝块稳定-细胞迁移-成骨分化级联调节研究
Lubin Liu,Zhiguo Wang,Yan Sun et al.
Lubin Liu et al.
Periodontal bone destruction caused by periodontitis presents a significant clinical challenge. Optimal regeneration of periodontal bone shall progress through three distinct physiological stages: 1) formation of a blood clot; 2) recruitmen...
Grancalcin Hydrogel Microneedle Patches Alleviate Sepsis via Modulation of Calcium Signaling to Augment Immune Cell Phagocytosis [0.03%]
胶质钙黏蛋白水凝胶微针贴片通过调节钙信号来增强免疫细胞吞噬作用从而缓解脓毒症
Peng Xiang,Mingyang Zhao,Yue He et al.
Peng Xiang et al.
Disorders in Ca2+ signaling contribute to many metabolic manifestations of sepsis and are one of the driving forces underlying multiorgan failure. Herein, a compensatory elevation in calcium-binding protein grancalcin (GCA) levels in monocy...
Synthesis of Phosphorescent Carbon Dot Composite with Redshift Emission by Annealing Treatment for Bioimaging [0.03%]
通过退火处理合成红移发射的磷光碳点复合材料用于生物成像
Mengyao Chen,Yuqi Zhang,Jiajia Ren et al.
Mengyao Chen et al.
Room-temperature phosphorescent carbon dots (RTP CDs) are promising afterglow materials applied in bioimaging owing to their long-lived emission and biocompatibility. Achieving RTP CDs with long emission wavelengths in aqueous environments ...
Chondrogenic Potential of Cryopreserved Aortic Allografts: Guiding Perichondrial Regeneration in Tracheal Repair [0.03%]
冷冻主动脉同种异体移植的软骨生成潜能：引导气管修复中的围软骨再生
Wan-Ting Hung,Kuan-Chuan Tsou,Huan-Chieh Cho et al.
Wan-Ting Hung et al.
Native tracheal cartilage exhibits limited regenerative capacity, making the search for suitable biomaterials for tracheal repair a persistent challenge. In this study, a non-decellularized cryopreserved aortic allograft (CAo) is investigat...
Precisely Tailored Annulated Porphyrin with Intense NIR Absorption for Highly Efficient Photothermal Therapy and Photoacoustic Imaging [0.03%]
高强度近红外吸收的 annulated 咔唑-卟啉用于高效光热治疗和光电成像
Chulin Qu,Chengyan Zhao,Yingzhe Hu et al.
Chulin Qu et al.
Constructing near-infrared (NIR) phototherapy agents with good biosafety is highly desirable for cancer therapy. Herein, the combined "β-meso-core" engineering of porphyrin produces excellent photothermal/photoacoustic agents that exhibit ...
A Nanoplatform Targeting Cascade Pathways for Enhanced Triptolide Delivery in Acute Kidney Injury Therapy [0.03%]
一种靶向级联途径的纳米平台 用于急性肾损伤治疗中的三磷腺苷增强型递送
Qianqian Guo,Xin Lu,Yanqi Zhang et al.
Qianqian Guo et al.
Triptolide (TP), the main active compound in Tripterygium wilfordii Hook F, has anti-inflammatory and antioxidant properties, making it a potential treatment option for acute kidney injury (AKI). However, the application of TP faces challen...