Development-Inspired Biomimetic Cell-Niche Coaggregates Safeguard Tooth Stem Cell-Based Functional Tissue Regeneration [0.03%]
发育启发的仿生细胞-基质聚集物保障牙髓干细胞功能组织再生能力
Xiao-Hui Zhang,Yi-De He,Hao Wang et al.
Xiao-Hui Zhang et al.
Harnessing natural developmental programs to repair and replace damaged organs represents promising approaches in regenerative medicine. However, effective strategies are still lacking for tissue regeneration in complicated conditions, such...
Mechanically and Chemically Defined PEG Hydrogels Improve Reproducibility in Human Cardioid Development [0.03%]
聚乙二醇水凝胶改善人类心脏发育重现性的研究
Yuanhui Song,Michael Seitz,Andrew Kowalczewski et al.
Yuanhui Song et al.
Cardioids are 3D self-organized heart organoids directly derived from induced pluripotent stem cells (hiPSCs) aggregates. The growth and culture of cardioids is either conducted in suspension culture or heavily relies on Matrigel encapsulat...
Ultrasmall Nanoparticles Mitigate Tau Hyperphosphorylation to Restore Synaptic Integrity and Boost Cognitive Function in Alzheimer's Disease [0.03%]
超小纳米颗粒通过缓解tau蛋白过度磷酸化来恢复阿尔茨海默病中的突触结构和认知功能
Hanbing Xu,Gang Wang,Zhilin Jiang et al.
Hanbing Xu et al.
Tau hyperphosphorylation represents a critical pathological hallmark of Alzheimer's disease (AD), a prevalent neurodegenerative disorder characterized by progressive cognitive decline. The ubiquitin-specific proteases 14 (USP14) impairs pro...
Correction to "ROS-Scavenging Hydrogels Synergize with Neural Stem Cells to Enhance Spinal Cord Injury Repair via Regulating Microenvironment and Facilitating Nerve Regeneration" [0.03%]
“ ROS清除水凝胶通过调节微环境和促进神经再生与神经干细胞协同作用以增强脊髓损伤修复”的纠正意见
Published Erratum
Advanced healthcare materials. 2025 May 15:e2501967. DOI:10.1002/adhm.202501967 2025
Fabrication of a Lipopolysaccharide-Targeting Peptide-Based Colloid for Alleviating Carbapenem-Resistant Enterobacteriaceae-Induced Cutaneous Infection [0.03%]
一种用于缓解碳青霉烯耐药肠杆菌科所致皮肤感染的脂多糖靶向肽类纳米(col)制剂的制备方法
Ping Zeng,Xinyi Ding,Chenyu Liu et al.
Ping Zeng et al.
Carbapenem-resistant Enterobacteriaceae (CRE) becomes a growing threat to human health. Many clinical isolates have shown strong resistance to commonly used antibacterial agents. Inspired by cationic amphiphiles with tandem-repeat sequence,...
Zn-Based Multi-Active Framework Nanoparticles TSA-CAN-Zn Inhibit Skin Glycation via Dual Blockade of HMGB1/RAGE and AGEs/RAGE Pathways [0.03%]
基于锌的多活性框架纳米粒子TSA-CAN-Zn通过双重阻断HMGB1/RAGE和AGEs/RAGE途径抑制皮肤糖基化
Cheng Yao,Heqi Wang,Jingxia Han et al.
Cheng Yao et al.
Receptor for advanced glycation end products (RAGE) plays an important role in skin glycation damage. High-mobility group 1B protein (HMGB1) and advanced glycation end products (AGEs) are key RAGE ligands. Simultaneous inhibition of HMGB1/R...
Pengfei Wu,Tian Zhang,Deyao Zhao et al.
Pengfei Wu et al.
Nucleic acid therapy demonstrates great potential in cancer treatment, infectious disease prevention, and vaccine development due to its advantages, such as rapid production, long-lasting effects, and high target specificity. Although nucle...
Engineered Chitosan-Derived Nanocarrier for Efficient siRNA Delivery to Peripheral and Central Neurons [0.03%]
高效递送siRNA进入周围神经细胞和中枢神经细胞的壳聚糖衍生成纳米载体
Ana P Spencer,Adriana Vilaça,Miguel Xavier et al.
Ana P Spencer et al.
Gene therapy using small interfering RNA (siRNA) holds promise for treating neurological disorders by silencing specific genes, like the phosphatase and tensin homolog (PTEN) gene, which restricts axonal growth. Effective siRNA delivery to ...
Piezoelectric Amplification of Cascade Enzymatic Catalysis and Nanomotor Propulsion for Synergistic Electrodynamic-Starvation Tumor Therapy [0.03%]
用于协同电动力-饥饿肿瘤治疗的压电放大级联酶催化和纳米电机推进技术
Zhanlin Zhang,Kun Wei,Jie Meng et al.
Zhanlin Zhang et al.
Piezoelectrodynamic therapy (PEDT) is compromised by hypoxia dilemma of tumors, while starvation therapy is constrained by insufficient enzyme activities. To address these challenges, Janus piezoelectric nanoparticles (NPs) are proposed to ...
A Biocompatible, Magnetic-Responsive Shape Memory Silicone Composite for Active Flow Controlling Valve [0.03%]
一种用于主动流动控制阀的生物相容性磁响应形状记忆硅胶复合材料
Yuchao Wu,Cheng Qiu,Congshan Mao et al.
Yuchao Wu et al.
A magnetically responsive shape memory silicone composite is developed for fabricating an active valve in biomedical fluidic systems. The composite consists of magnetic neodymium-iron-boron (NdFeB) microparticles (MPs) and poly(glycerol-dod...