Flexible and Environmentally Friendly Calcium Polyphosphate Hydrogels: Toward Inorganic Functional Materials for Wearable Devices and Soft Actuators [0.03%]
用于可穿戴设备和软致动器的无机功能材料：柔性和环保的聚磷酸钙水凝胶
Tongtong Zhou,Jiulong Zhou,Song Zhang et al.
Tongtong Zhou et al.
Inorganic hydrogels have attracted significant interest in materials science. However, it is a big challenge to fabricate flexible and multifunctional inorganic hydrogels due to the inherent rigidity of traditional inorganic materials. Here...
Injectable Alginate/β-TCP Composite Hydrogel Incorporating P34HB/MgO+PEG Coaxial Electrospun Microfibers for Minimally Invasive Treatment of Osteonecrosis [0.03%]
一种可注射藻酸盐/β-磷酸三钙复合水凝胶，用于微创治疗骨坏死
Yu Hu Zhou,Zi Hao Zou,Jian Xiang Teng et al.
Yu Hu Zhou et al.
Avascular necrosis of the femoral head (ANFH) is a debilitating musculoskeletal disorder that is typically caused by impaired blood supply to the hip joint. In treating irregular bone defects that resulted from ANFH, injectable hydrogels ar...
Emily K Augustine,Adrian Camarena,Taylor R Klein et al.
Emily K Augustine et al.
Rib fractures are common among blunt chest trauma patients and are a hallmark of severe thoracic injury with high morbidity and mortality rates. The standard treatment of most rib fracture cases is limited to pain control and respiratory su...
CLDN18.2 CAR-derived Extracellular Vesicle Immunotherapy Improves Outcome in Murine Pancreatic Cancer [0.03%]
CLDN18.2 CAR衍生的外泌体免疫治疗改善了小鼠胰腺癌的预后
Yue Qing,Ke Jiang,Hua Jiang et al.
Yue Qing et al.
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal malignancies, with no current effective treatment options. Chimeric antigen receptor (CAR) T cell therapy represents a powerful immunotherapeutic approach but faces majo...
Exercise Mimetic Exosomes Re-establish the Extracellular Matrix Metabolic Balance and Alleviate the Inflammatory Macrophage Infiltration in Intervertebral Disc Degeneration [0.03%]
运动模拟外泌体可重建椎间盘代谢平衡微环境并减轻炎症巨噬细胞浸润
Ke Zhao,Yongzhi Cui,Yuxuan Du et al.
Ke Zhao et al.
Extracellular matrix (ECM) metabolic imbalance and macrophage infiltration, induced by degenerated nucleus pulposus cells (NPCs), represent key pathological alterations in intervertebral disc degeneration (IVDD). Physical exercise is shown ...
Engineering the Micro-Nano Hierarchical Spray Hydrogel for Acute Lung Injury Therapy [0.03%]
用于急性肺损伤治疗的微纳米分级喷雾水凝胶的制备
Yongxin Xu,Rui Zhao,Peipei Xi et al.
Yongxin Xu et al.
Acute lung injury (ALI) poses a significant threat to human health, yet specific treatments remain elusive. Despite extensive research efforts, drug delivery to the lungs and reliable preclinical models are major challenges. To address thes...
Biomimetic Scaffolds Enhance iPSC Astrocyte Progenitor Angiogenic, Immunomodulatory, and Neurotrophic Capacity in a Stiffness and Matrix-Dependent Manner for Spinal Cord Repair Applications [0.03%]
一种用于脊髓修复的类组织支架可增强多能干细胞源性少突胶质前体细胞促血管生成、免疫调节和神经保护潜能
Cian O&#x;Connor,Ian Woods,Sarah F McComish et al.
Cian O&#x;Connor et al.
Spinal cord injury repair poses a significant challenge due to the hostile microenvironment of the injury site and the poor survival and function of clinically relevant transplanted cells. Here it is aimed to investigate whether tuning the ...
Albumin Corona Overturns Long-Acting Behaviors of Myristic Acid-Conjugated Quetiapine Nanosuspension [0.03%]
表面活性剂诱导的白蛋白冠状体逆转了肉豆蔻酸奎硫平纳米混悬液的行为特性
Hy Dinh Nguyen,Hai Van Ngo,Beom-Jin Lee
Hy Dinh Nguyen
This work aimed to investigate the interaction of a self-assembled myristic acid-conjugated quetiapine nanosuspension (QMN) with human serum albumin and its overturning effect on QMN's long-acting performance. Albumin corona formation modif...
Enhanced Photodynamic Therapy Synergizing with Neutrophil Recruitment Boosts Drug-Resistant Bacterial Clearance [0.03%]
增强的光动力疗法与中性粒细胞募集协同作用，增强了对耐药细菌的清除作用
Anran Li,Jie Li,Yufei Zhang et al.
Anran Li et al.
Antibiotic-resistant bacteria produce some virulence factors as immune evasion molecules that interfere with a variety of innate immune defenses, which is associated with reduced levels of neutrophil recruitment. Antibiotics and neutrophils...
Integrated Iontronic FMG-sEMG Sensing for Decoding Muscle Activation Mechanisms and Force Assessment [0.03%]
集成离子电子FMG-sEMG传感技术 解码肌肉激活机制和评估力量大小
Peikai Zou,Junhan Wang,Xian Zhao et al.
Peikai Zou et al.
Muscle activity generates both physiological electrical and mechanical signals, the monitoring of which is crucial in rehabilitation and sports medicine, underpinning effective diagnosis, treatment, and rehabilitation processes. Advances in...