An Ultra-Flexible Neural Electrode with Bioelectromechanical Compatibility and Brain Micromotion Detection [0.03%]
一种与生物机电相容并能检测脑微动的超柔性神经电极
Donglei Chen,Yu Lu,Shuo Zhang et al.
Donglei Chen et al.
Neural electrodes, as core components of brain-computer interfaces(BCIs), face critical challenges in achieving stable mechanical coupling with brain tissue to ensure high-quality signal acquisition. Current flexible electrodes, including s...
Cell Calcification Models and Their Implications for Medicine and Biomaterial Research [0.03%]
细胞钙化模型及其在医学和生物材料研究中的意义
Luke Hunter,Caterina Vanelli Coralli,Robert Dzhanaev et al.
Luke Hunter et al.
The evolutionary significance of calcium-based minerals is highlighted by the division of life between those animals with backbones (vertebrates) and those without (invertebrates). Calcification, or biomineralization, is the process by whic...
Molecular Simulations of Polymer-based Drug Nanocarriers: From Physical and Structural Properties to Controlled Release [0.03%]
基于聚合物的药物纳米载体的分子模拟：从物理和结构性质到控制释放
Ping Gao,Xin Jiang,Jinyu Li et al.
Ping Gao et al.
Polymer-based drug delivery systems have been extensively studied to overcome the limitations of free drug administration (e.g., poor solubility and stability, rapid degradation and early metabolization, short plasma half-life, low therapeu...
Theranostic Probiotic Engineered Living Materials That Dynamically Respond to Inflammation Markers [0.03%]
一种工程化益生菌治疗诊断材料可动态响应炎症标志物
Gokce Altin-Yavuzarslan,Sierra M Brooks,James O Park et al.
Gokce Altin-Yavuzarslan et al.
The development of smart, implantable devices localized at the site of inflammation to conditionally and proactively combat active inflammation for inflammatory bowel disease (IBD), has the potential to transform the patient's quality of li...
Granular Hydrogels as Modular Biomaterials: From Structural Design to Biological Responses [0.03%]
颗粒水凝胶作为模块化生物材料：从结构设计到生物学响应
Asmasadat Vaziri,Renata Maia,Pei Zhang et al.
Asmasadat Vaziri et al.
Over the past decade, granular hydrogels have been widely utilized as a cell-free or cell-laden platform to deliver therapeutics (e.g., cells and drugs) for tissue repair, or as a bioink or supporting bed for bioprinting. Owing to their inh...
Hybrid Ultrasound-Enhanced and Self-Cascade-Catalysis-Mediated System with Lewis Acid Active Centers for Treating MRSA-Infected Osteomyelitis [0.03%]
含路易斯酸活性中心的混合超声增强和自级联催化体系介导的耐甲氧西林金黄色葡萄球菌感染型骨髓炎治疗体系
Panyue Liu,Shuxin Lu,Hao Cheng et al.
Panyue Liu et al.
Conventional nanoenzymes for treating methicillin-resistant Staphylococcus aureus (MRSA)-infected osteomyelitis face serious limitations, including instability caused by valence cycling and impaired reactive oxygen species (ROS) generation ...
Biodegradable Implantable Electronics with Wireless Technology for Real-Time Clinical Applications [0.03%]
具有无线技术的可降解植入式电子产品用于实时临床应用
Myeongki Cho,Jeong Woo Chae,Young-Jin Park et al.
Myeongki Cho et al.
Wireless biodegradable electronics offer a transformative approach to transient biomedical applications by combining fully implantable, resorbable architectures with untethered communication and power delivery. These systems address key lim...
Ilayda Namli,Deepak Gupta,Yogendra Pratap Singh et al.
Ilayda Namli et al.
The complex architecture of the cornea, characterized by specifically organized collagen fibrils and distinct cellular layers, poses significant challenges for traditional tissue engineering strategies to replicate its native function. 3D B...
Methotrexate-Loaded Liposomal Formulation Enables 6-Week Sustained Intraocular Therapeutic Drug Release in a Porcine Model [0.03%]
载甲氨蝶呤脂质体的玻璃体内植入剂在猪眼模型中实现为期六周的持续给药治疗释放研究
Maximilian Hammer,Lea Skrzypczyk,Sabrina Wohlfart et al.
Maximilian Hammer et al.
Methotrexate (MTX) inhibits cell proliferation, which underlies ocular diseases, including intraocular lymphoma and proliferative vitreoretinopathy. However, MTX normally requires bi-weekly intravitreal injections due to a short half-life, ...
Wenqiang Ma,Rui Ding,Siyuan Wang et al.
Wenqiang Ma et al.
Periodontitis is a destructive disease that causes irreversible damage to periodontal supporting tissues, posing a serious threat to patients' oral health. Given the insidious nature of periodontal tissue destruction, early diagnosis of per...