Dual-Bionic Wearable Platform with Neighborhood Electrochemical Biosensor and Janus Fabric for Unidirectional Sweat Sampling and Analysis [0.03%]
用于单向汗液采样和分析的双仿生可穿戴平台及邻近电化学生物传感器和Janus织物
Chaohuan Yang,Shuyi Li,Chenchen Liao et al.
Chaohuan Yang et al.
Achieving optimal skin comfort and good sensitivity is highly necessary for sweat detection in a wearable electrochemical sensor. Herein, this study develops a comfortable wearable platform consisting of Janus patterned cotton fabric (PCF) ...
Multi-Modal Therapy for Diabetic Ulcers: A Hydrogel Platform Combining Antibacterial, Oxygenating, ROS-Scavenging, and Pro-Healing Functions [0.03%]
一种用于糖尿病溃疡的多模式治疗水凝胶平台：抗菌、富氧、清除ROS和促进伤口愈合多功能集成体系
Yang Li,Peng Zhao,Zhennan Fang et al.
Yang Li et al.
Diabetic ulcers, characterized by excessive accumulation of reactive oxygen species (ROS), local hypoxia, persistent inflammation, and secondary bacterial infection, pose a serious threat to human health. To address these challenges, this s...
Versatile Hyaluronic Acid Hydrogels via pH-Induced Gelation for Multifaceted Cutaneous Wound Healing [0.03%]
多功能透明质酸水凝胶促进皮肤伤口的多模式治疗
Xiaoxue Yang,Kefan Wu,Yi Liu et al.
Xiaoxue Yang et al.
Hyaluronic acid (HA) hydrogels have attracted growing interest for skin regeneration. However, conventional fabrication approaches for HA hydrogels often require complex chemical modifications, leading to prolonged preparation cycles, incon...
Qing Chen,Shumin Liang,Tao Chen et al.
Qing Chen et al.
While three - dimensional (3D) printing enables fabrication of hollow geometries through precise ink deposition, its reliance on photo- or thermal-curing often compromises resolution and biocompatibility. Alternatively, aqueous-phase chemic...
Smart Theranostic Nanogels with Swelling-Driven Contrast for Multimodal Imaging, Sensing, and Photothermal Breast Cancer Ablation [0.03%]
一种用于多模影像、检测和光热乳腺癌消融的智能治疗纳米凝胶
Alice Sciortino,Maurizio Marrale,Cesare Gagliardo et al.
Alice Sciortino et al.
Integrating multimodal imaging and therapeutic functions into a single, stimuli-responsive nanoplatform for minimally invasive cancer therapy remains a major obstacle for theranostic nanomedicines. Most existing nanomedicines fail to sense ...
Dual-Nanocomplex Delivery of Neoantigen Vaccines and Doxorubicin for Synergistic Chemo-Immunotherapy against Colorectal Cancer [0.03%]
双纳米复方递送新抗原疫苗和多柔比星联合治疗结直肠癌
Weijian Zhao,Khattak Sameena Noor,Siyu Sun et al.
Weijian Zhao et al.
Colorectal cancer (CRC) is still an important global health challenge, with limited treatment efficacy. Neoantigen-based cancer vaccines offer tumor-specific immune activation but are limited by poor immunogenicity and rapid degradation, wh...
NIR-Triggered Janus Nanofiber Dressing with Synergistic Photodynamic Antibacterial Action and Sustained Oxygen Release for Accelerated Healing of Infected Wounds [0.03%]
用于感染伤口快速愈合的近红外触发Janus纳米纤维敷料，具有协同光动力抗菌作用和持续氧释放功能
Xiaoyong Huang,Bo Tian,Zhaojie Sun et al.
Xiaoyong Huang et al.
Impaired wound healing poses life-threatening risks due to uncontrolled multidrug-resistant bacterial infections. Although photodynamic therapy (PDT) represents a promising non-antibiotic strategy to combat antibiotic-resistant pathogens, i...
A Microphysiological Interface of Skeletal Myobundles and Inflamed Adipose Tissue for Recapitulating Muscle Dysfunction in an Obese Microenvironment [0.03%]
一种微生理界面，用于再现肥胖微环境中肌肉功能障碍的小骨骼肌索和发炎的脂肪组织
Seunggyu Kim,Tianxin Cao,Zhengpeng Wan et al.
Seunggyu Kim et al.
Systemic inflammation associated with obesity impairs skeletal muscle function through paracrine signaling from intermuscular adipose tissue-adipose depots situated between adjacent skeletal muscle groups-as well as from visceral adipose ti...
Fibrin-Targeting Metal-Organic Framework Nanoagent for NIR-Triggered Photothermal Thrombus Ablation [0.03%]
一种针对纤维蛋白的金属有机框架纳米剂用于近红外触发的光热血栓消融
Yu-Liang Chen,Ming-Hsin Liu,Ming-Feng Hsieh et al.
Yu-Liang Chen et al.
Thrombosis remains a leading cause of mortality worldwide; however, current thrombolytic therapies suffer from limited thrombus targeting, poor penetration, and systemic side effects. To address these challenges, a fibrin-targeting photothe...
Autonomous Soft Nanorobots for Active Targeting and Therapy of Triple-Negative Breast Cancer [0.03%]
用于三阴乳腺癌主动靶向及治疗的自主软纳米机器人
Wei Lu,Jiaxin Rui,Guangshu Zhou et al.
Wei Lu et al.
The extensive connective tissue proliferation and dense extracellular matrix (ECM) in triple-negative breast cancer (TNBC) form abnormal physical barriers that impede the penetration of nanomedicines and hinder therapeutic efficacy. Herein,...