Concise syntheses of natural diarylheptanoids containing a 1,4-pentadiene unit [0.03%]
含1,4-戊二烯单元的天然茋类化合物的简洁合成
Guang Tao,Xin-Yue Hu,Hong-Xing Liu et al.
Guang Tao et al.
Two concise and efficient synthetic routes were developed for the synthesis of three 1,7-diarylheptanoids (1-3) containing a 1,4-pentadiene unit, which were originally isolated from Ottelia acuminata var. acuminata. The first approach focus...
Six pairs of enantiomeric prenylated flavonoids with cytotoxic activities from Epimedium sagittatum Maxim [0.03%]
具细胞毒性的六对映叶绿素异戊二烯基黄酮类化合物从Epimedium sagittatum Maxim中获得
Shuang-Shuang Xie,Xiang Yu,Qi-Mei Tie et al.
Shuang-Shuang Xie et al.
In this work, six pairs of undescribed enantiomeric prenylated flavonoids, ( ±)-epimesatines J-O (1a/1b-6a/6b), were isolated from the aerial parts of Epimedium sagittatum Maxim. Their structures and absolute configurations were determined...
Therapeutic targeting of ocular diseases with emphasis on PI3K/Akt, and OPRL pathways by Hedera helix L. saponins: a new approach for the treatment of Pseudomonas aeruginosa-induced bacterial keratitis [0.03%]
以PI3K/Akt和OPRL途径为靶点治疗眼部疾病并重点强调用L. 虎耳草皂苷治疗绿脓杆菌引起的细菌性角膜炎的一种新方法
Sherif A Hamdy,Shymaa Hatem,Heba Elosaily et al.
Sherif A Hamdy et al.
Pseudomonas aeruginosa-induced bacterial keratitis is one of the most sight-threatening corneal infections associated with intense ocular inflammatory reactions that may lead to vision loss. Hence, this study investigated the efficacy of th...
New sesquiterpenoids with anti-inflammatory effects from phytopathogenic fungus Bipolaris sorokiniana 11134 [0.03%]
来源于植物病原菌尖孢镰刀菌11134的具有抗炎活性的新倍半萜类化合物
Qiang Yin,Jianying Han,Guixiang Yang et al.
Qiang Yin et al.
Sesquiterpenoids represent a structurally diverse class of natural products widely recognized for their ecological significance and pharmacological potential, including antimicrobial, anti-inflammatory, and anticancer properties. As part of...
Inhibitory effects of corylin derived from aerial part of Pueraria lobata on melanin synthesis and potential applications in skin whitening and photoaging management [0.03%]
来源于地上部分的钩藤素Pueraria lobata抑制黑色素合成的作用及在皮肤美白和光老化管理中的潜在应用
BoYoon Chang,SungYeon Kim
BoYoon Chang
Purpose: This study aimed to investigate the potential of corylin, a bioactive compound isolated from the aerial part of Pueraria lobata, as a novel skin-whitening agent. Specifically, the research sought to evaluate its ...
Phthalide mono- and dimers from the rhizomes of Angelica sinensis and their anti-inflammatory activities [0.03%]
Angelica sinensis rhizome中的苯并呋喃类化合物及其抗炎活性
Hongyan Wen,Sheng Li,Yu Zhang
Hongyan Wen
Three pairs of enantiomeric phthalide dimers, including two new ones, angesicolides A (1) and B (2), and a new phthalide monomer (3), were obtained from the rhizomes of Angelica sinensis. Their structures were established through spectrosco...
Natural anticancer agents: prospection of medicinal and aromatic plants in modern chemoprevention and chemotherapy [0.03%]
天然抗癌剂——药用和芳香植物在现代化学预防及化疗中的筛选与应用研究
Patricia Quintero-Rincón,Karina Caballero-Gallardo,Jesus Olivero-Verbel
Patricia Quintero-Rincón
Natural products obtained from medicinal and aromatic plants are increasingly recognized as promising anticancer agents due to their structural richness, including terpene and flavonoid molecules, which induce apoptosis and modulate gene ex...
Activation of SIK1 by phanginin A regulates skeletal muscle glucose uptake by phosphorylating HADC4/5/7 and enhancing GLUT4 expression and translocation [0.03%]
活性剂phanginin A通过使HADC4/5/7磷酸化激活SIK1并通过促进GLUT4表达和易位来调节骨骼肌葡萄糖摄取
Yu Shi,Xing-de Wu,Yanli Liu et al.
Yu Shi et al.
Salt-inducible kinase 1 (SIK1) participates in various physiological processes, yet its involvement in regulating skeletal muscle glucose uptake remains unclear. Previously, we showed that phanginin A, a natural compound isolated from Caesa...
Xylariaides A and B, novel cytochalasans with a unique 5/6/5/3 ring system from a soil fungus Xylaria sp. Y01 [0.03%]
来源于土壤真菌Xylaria sp. Y01的具有独特5/6/5/3并合环体系的两个新的倍半萜化合物Xylariaides A和B
Yi-Yun Yuan,Yan Li,Wen-Yu Lu et al.
Yi-Yun Yuan et al.
Two new cytochalasans, xylariaides A (1) and B (2), were isolated and identified from a soil fungus Xylaria sp. Y01. Their structures were unambiguously determined by extensive spectroscopic methods including high resolution electrospray io...
Structurally diverse polyketides and alkaloids produced by a plant-derived fungus Penicillium canescens L1 [0.03%]
来源于植物内生真菌Penicillium canescens L1的结构性多样的聚酮和生物碱类代谢产物研究
Wei-Ye Wu,Xun Wei,Qiong Liao et al.
Wei-Ye Wu et al.
A series of structurally diverse polyketides (1-3), sesterterpenoids (24 and 25), and alkaloids (26-34) were isolated from the fermentation of a plant-derived fungus Penicillium canescens L1 on solid rice medium. Among these secondary metab...