Partial-volume correction in dynamic PET-CT: effect on tumor kinetic parameter estimation and validation of simplified metrics [0.03%]
动态PET-CT中的部分容积校正及其对肿瘤动力学参数估计和简化指标验证的影响
M C F Cysouw,S V S Golla,V Frings et al.
M C F Cysouw et al.
Background: Partial-volume effects generally result in an underestimation of tumor tracer uptake on PET-CT for small lesions, necessitating partial-volume correction (PVC) for accurate quantification. However, investigati...
Phase analysis single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) detects dyssynchrony in myocardial scar and increases specificity of MPI [0.03%]
相位分析单光子发射计算机断层扫描心肌灌注成像可检测瘢痕组织心肌不同步并提高其检查的特异性
John P Bois,Chris Scott,Panithaya Chareonthaitawee et al.
John P Bois et al.
Background: Myocardial perfusion imaging (MPI) with single-photon emission computed tomography (SPECT) is commonly used to assess patients with cardiovascular disease. However, in certain scenarios, it may have limited sp...
Efficacy of 4'-[methyl-11C] thiothymidine PET/CT before and after neoadjuvant therapy for predicting therapeutic responses in patients with esophageal cancer: a pilot study [0.03%]
4'-[methyl-11C]噻替帕啶正电子发射断层扫描/计算机断层扫描(PET/CT)预测新辅助治疗前后食管癌患者疗效的可行性研究：一项前瞻性队列试点研究
Masatoshi Hotta,Ryogo Minamimoto,Kazuhiko Yamada et al.
Masatoshi Hotta et al.
Background: 4'-[Methyl-11C] thiothymidine (4DST) has been introduced as a new cell proliferation imaging PET tracer that incorporates into DNA directly. The aim of this prospective study was to evaluate the efficacy of 4D...
Pulmonary PET imaging confirms preferential lung target occupancy of an inhaled bronchodilator [0.03%]
肺部PET成像证实吸入性支气管扩张剂的优先肺靶点占有率
Magnus Schou,Pär Ewing,Zsolt Cselenyi et al.
Magnus Schou et al.
Background: Positron emission tomography (PET) is a non-invasive molecular imaging technique that traces the distribution of radiolabeled molecules in experimental animals and human subjects. We hypothesized that PET coul...
Monitoring anti-PD-1-based immunotherapy in non-small cell lung cancer with FDG PET: introduction of iPERCIST [0.03%]
基于抗PD-1的免疫治疗非小细胞肺癌的FDG PET监测：介绍iPERCIST标准
Lucas Goldfarb,Boris Duchemann,Kader Chouahnia et al.
Lucas Goldfarb et al.
Background: Immunotherapy represents a new therapeutic approach in non-small cell lung carcinoma (NSCLC) with the potential for prolonged benefits. Because of the systemic nature and heterogeneity of tumoral diseases, as ...
Impact of a combination of quantitative indices representing uptake intensity, shape, and asymmetry in DAT SPECT using machine learning: comparison of different volume of interest settings [0.03%]
基于机器学习的多巴胺转运体单光子发射计算机断层成像术定量指标组合应用效果：不同感兴趣区设置下的比较
Yu Iwabuchi,Tadaki Nakahara,Masashi Kameyama et al.
Yu Iwabuchi et al.
Background: We sought to assess the machine learning-based combined diagnostic accuracy of three types of quantitative indices obtained using dopamine transporter single-photon emission computed tomography (DAT SPECT)-spe...
Comparison of standardized uptake values between 99mTc-HDP SPECT/CT and 18F-NaF PET/CT in bone metastases of breast and prostate cancer [0.03%]
99mTc-HDP SPECT/CT与18F-NaF PET/CT在乳腺癌和前列腺癌骨转移中标准摄取值的比较研究
Samuli Arvola,Ivan Jambor,Anna Kuisma et al.
Samuli Arvola et al.
Background: Despite recent technological advances allowing for quantitative single-photon emission computed tomography (SPECT), quantitative SPECT has not been widely used in the clinical practice. The aim of this study i...
Targeting mannose receptor expression on macrophages in atherosclerotic plaques of apolipoprotein E-knockout mice using 68Ga-NOTA-anti-MMR nanobody: non-invasive imaging of atherosclerotic plaques [0.03%]
使用68Ga-NOTA-抗MMR纳米抗体靶向阿波罗蛋白E基因敲除小鼠动脉粥样硬化斑块中巨噬细胞上甘露糖受体的表达：非侵入性成像动脉粥样硬化斑块
Zohreh Varasteh,Sarajo Mohanta,Yuanfang Li et al.
Zohreh Varasteh et al.
Background: Rupture-prone atherosclerotic plaques are characterized by heavy macrophage infiltration, and the presence of certain macrophage subsets might be a sign for plaque vulnerability. The mannose receptor (MR, CD20...
18F-FDG and 11C-4DST PET/CT for evaluating response to platinum-based doublet chemotherapy in advanced non-small cell lung cancer: a prospective study [0.03%]
评估基于顺铂双联化疗的新发或进展的晚期非小细胞肺癌的18F-FDG和11C-4DST正电子发射断层扫描/计算机断层扫描：一项前瞻性研究
Ryogo Minamimoto,Yuichiro Takeda,Masatoshi Hotta et al.
Ryogo Minamimoto et al.
Background: 4'-[Methyl-11C] thiothymidine (4DST) PET/CT provides DNA synthesis imaging, which represented a higher correlation with the proliferation in advanced non-small cell lung cancer (NSCLC) than that from imaging w...
A phase 1, first-in-human study of 18F-GP1 positron emission tomography for imaging acute arterial thrombosis [0.03%]
用于急性动脉血栓成像的18F-GP1正电子发射断层扫描首次人体一期研究
Sun Young Chae,Tae-Won Kwon,Soyoung Jin et al.
Sun Young Chae et al.
Background: 18F-GP1 is a novel positron emission tomography (PET) tracer that targets glycoprotein IIb/IIIa receptors on activated platelets. The study objective was to explore the feasibility of directly imaging acute ar...