Neuromelanin-targeted 18F-P3BZA PET/MR imaging of the substantia nigra in rhesus macaques [0.03%]
靶向神经黑素的18F-P3BZA正电子发射断层磁共振成像融合技术在恒河猴黑色素浓集区中的应用
Hongyan Feng,Ning Tu,Ke Wang et al.
Hongyan Feng et al.
Background: Neuromelanin is mostly located in dopaminergic neurons in the substantia nigra (SN) pars compacta, and can be detected by magnetic resonance imaging (MRI). It is a promising imaging-base biomarker for neurolog...
Radiosensitization of NET cells by HSP90 inhibitor ganetespib is mediated through pleiotropic stress responses [0.03%]
HSP90抑制剂ganetespib通过多效性应激反应对NET细胞的放射增敏作用
Pleun A M Engbers,Thom G A Reuvers,José María Heredia-Genestar et al.
Pleun A M Engbers et al.
Background: Peptide receptor radionuclide therapy (PRRT) employing [177Lu]Lu-[DOTA-Tyr3]octreotate has been established as treatment for patients with metastatic neuroendocrine tumors (NETs) that overexpress the somatosta...
First-in-human intranasal [13N]oxytocin PET: evaluation of feasibility, biodistribution, and radiation dosimetry [0.03%]
人鼻内[13N]催产素PET可行性、生物分布和辐射剂量的评估研究
Michael Winterdahl,Erik Nguyen Nielsen,Søren B Hansen et al.
Michael Winterdahl et al.
Background: Oxytocin is a neuropeptide with therapeutic potential for several neuropsychiatric and pain-related disorders. Intranasal delivery is proposed to enable access to the central nervous system via the trigeminal ...
Molecular targets and the emerging role of copper radionuclides in prostate cancer theranostics [0.03%]
前列腺癌诊疗中分子靶点与铜同位素放射核素的新兴作用
Diana Rodrigues,Alexandra I Fonseca,João N Moreira et al.
Diana Rodrigues et al.
Background: Prostate cancer (PCa) remains one of the most commonly diagnosed malignancies and a leading cause of cancer-related morbidity and mortality among men worldwide. Despite considerable progress in diagnostic and ...
Local staging of de novo prostate cancer using mpMRI, PSMA-PET and PSMA-PET/mpMRI - a comparative study [0.03%]
利用mpMRI、PSMA- PET及PSMA-PET/ MRI进行前列腺癌的局部病期比较研究
Josefine Grefve,Sara N Strandberg,Joakim Jonsson et al.
Josefine Grefve et al.
Background: Accurate diagnosis and staging are essential for optimal treatment planning of prostate cancer. By combining functional and anatomical imaging, PSMA-PET/mpMRI offers a potential to improve lesion detection and...
Correction: 89Zr-labeled ImmunoPET targeting the cancer stem cell antigen CD133 using fully-human antibody constructs [0.03%]
纠正：使用全人源抗体构建子标记靶向癌症干细胞抗原CD133的89Zr-ImmunoPET
Kevin Wyszatko,Melissa Chassé,Nancy Janzen et al.
Kevin Wyszatko et al.
Published Erratum
EJNMMI research. 2025 Nov 4;15(1):134. DOI:10.1186/s13550-025-01331-6 2025
Bimodality imaging as a companion to evaluate antitumour efficacy of TH-302 in experimental chondrosarcoma [0.03%]
TH-302抗肿瘤疗效的评价新方法——软骨肉瘤双模态成像研究
Roxane Autissier,Guilhem Pagés,Erwan Boutault et al.
Roxane Autissier et al.
Background: The hypoxic status of cancer tumour is disparate within tumour microenvironment and is considered as the main cause of treatment resistance. Chondrosarcoma, a type of bone cancer, combines heterogonous tumour ...
In vivo gastrin releasing peptide receptor expression in SDH deficient wild-type gastrointestinal stromal tumours (GIST): potential for theranostic applications [0.03%]
胃肠道间质肿瘤(GIST)中体内释放胃泌素肽受体表达：SDH缺乏型野生GIST的治疗诊断应用潜力评估研究
David G E Hulse,Ines Harper,Fung Tan et al.
David G E Hulse et al.
Background: Succinate dehydrogenase (SDH) deficient wild-type Gastrointestinal Stromal Tumours (wtGIST) are a rare GIST subtype with limited treatment options. Gallium-68 labelled Gastrin Releasing Peptide Receptor (GRPR)...
A feasibility study of [18F] FDG PET/CT radiomics in predicting high-risk cytogenetic abnormalities in multiple myeloma [0.03%]
18F-FDG PET/CT影像组学预测多发性骨髓瘤高危细胞遗传学异常的可行性研究
Hong Chen,Jingxin Han,Haozhe Huang et al.
Hong Chen et al.
Background: Multiple myeloma (MM) is a heterogeneous malignancy with prognosis significantly affected by high-risk cytogenetic abnormalities (HRCAs). Traditional detection using fluorescence in situ hybridisation is invas...
Quantitative terbium-161 SPECT/CT imaging: demonstrating the feasibility of image-based dosimetry and highlighting pitfalls [0.03%]
定量的钷-161 SPECT/CT 成像：基于影像学剂量学的可行性及潜在问题展示
Frida Westerbergh,Nicholas P van der Meulen,Cristina Müller et al.
Frida Westerbergh et al.
Background: Terbium-161 (161Tb) is a promising β⁻-emitter for theragnostics. However, its complex photon emission pattern-including intense X-rays and low-yield, high-energy γ-emissions-may complicate image-based quant...