Nutrient-supplemented propagation of Saccharomyces cerevisiae improves its lignocellulose fermentation ability [0.03%]
营养补充提高酵母菌的纤维素发酵能力
Marlous van Dijk,Friederike Mierke,Yvonne Nygård et al.
Marlous van Dijk et al.
Propagation conditions have been shown to be of considerable importance for the fermentation ability of Saccharomyces cerevisiae. The limited tolerance of yeast to inhibitors present in lignocellulosic hydrolysates is a major challenge in s...
Bioconversion of biphenyl to a polyhydroxyalkanoate copolymer by Alcaligenes denitrificans A41 [0.03%]
假单胞菌A41利用联苯合成聚羟基脂肪酸酯共聚物的过程
Taito Yajima,Mizuki Nagatomo,Aiko Wakabayashi et al.
Taito Yajima et al.
A polyhydroxyalkanoate (PHA) copolymer, poly(3-hydroxybutyrate-co-3-hydroxyvalerate) [P(3HB-co-3HV)], was biosynthesized from biphenyl as the sole carbon source using Alcaligenes (currently Achromobacter) denitrificans A41. This strain is c...
Microbiome and metabolic changes in milk in response to artemisinin supplementation in dairy cows [0.03%]
青蒿素补充对奶牛牛奶微生物群和代谢物的影响
Kun Hou,Jinjin Tong,Hua Zhang et al.
Kun Hou et al.
This study aimed to explore the effects of artemisinin (ART) on the milk microbiome and metabolites of dairy cow. A total of 12 mid-lactation Holstein dairy cows with similar parity, days in milk were randomly divided into 2 groups receivin...
Identification of residues for chaperone-like activity of OppA protein in Yersinia pseudotuberculosis [0.03%]
鼠疫耶尔森菌中OppA蛋白分子伴娘活性相关氨基酸位点的鉴定
Elena Escobar Garduño,Thomas Scior,Lucia Soto Urzúa et al.
Elena Escobar Garduño et al.
Periplasmic oligopeptide binding protein (OppA) is part of a multimeric cytoplasmic membrane protein complex, whose function is known as peptide transporters found in Gram-negative bacteria. A chaperone-like activity has been found for the ...
Generation of a recombinant chickenized monoclonal antibody against the neuraminidase of H9N2 avian influenza virus [0.03%]
针对H9N2禽流感病毒神经氨酸酶的重组鸡单克隆抗体的生成
Fei Wang,Yajuan Wang,Zhimin Wan et al.
Fei Wang et al.
We previously reported a monoclonal antibody (mAb), 1G8, against the neuraminidase (NA) of H9N2 avian influenza virus (AIV) with significant NA inhibitory activity. To generate a recombinant chickenized mAb (RCmAb) against the NA of H9N2 AI...
The inhibitory effects of metabolites from Bacillus pumilus on potato virus Y and the induction of early response genes in Nicotiana tabacum [0.03%]
枯草芽孢杆菌代谢物对Y株土豆病毒的抑制作用及烟草早期响应基因的诱导作用
Shuo Shen,Wei Li
Shuo Shen
To develop a new antiviral preparation from a microbial source, the halophilic bacterium Bacillus pumilus E303035 was isolated from a soil sample collected at Qarhan Salt Lake in Qinghai, China. The inhibitory activity of an ethyl acetate e...
MicroRNA-1179 suppresses the proliferation and enhances vincristine sensitivity of oral cancer cells via induction of apoptosis and modulation of MEK/ERK and PI3K/AKT signalling pathways [0.03%]
MicroRNA-1179通过诱导凋亡和调节MEK/ERK及PI3K/AKT信号通路抑制口腔癌细胞增殖并增强长春新碱敏感性
Yanmei Gao,Hanmei Xu,Tiemin Pu
Yanmei Gao
The role of miR-1179 in the development of cancer has been proved by different studies. However, the expression profile and role of miR-1179 is yet to be explored in human oral cancer. Consistently, this study was undertaken to explore the ...
Mukonal exerts anticancer effects on the human breast cancer cells by inducing autophagy and apoptosis and inhibits the tumor growth in vivo [0.03%]
Mukonal通过诱导自噬和凋亡对人乳腺癌细胞产生抗癌作用，并抑制体内肿瘤生长
Wenbiao Wang,Zhengui Zhou,Xiaohong Zhou et al.
Wenbiao Wang et al.
Mukonal is an active member of carbazole alkaloids isolated from Murraya koenigii. It has been shown to possess remarkable biological and pharmacological activities including anticancer activity. Therefore, the aim of current investigation ...
Efficient ammonia production from food by-products by engineered Escherichia coli [0.03%]
工程化大肠杆菌有效转化食物副产品生产氨气
Yuki Tatemichi,Kouichi Kuroda,Takeharu Nakahara et al.
Yuki Tatemichi et al.
Ammonia is used as a fertilizer for agriculture, chemical raw material, and carrier for transporting hydrogen, and with economic development, the demand for ammonia has increased. The Haber-Bosch process, which is the main method for produc...
Thomas Isbrandt,Jens C Frisvad,Anja Madsen et al.
Thomas Isbrandt et al.
Three new azaphilones, sassafrin E (1), sassafrin F (2), and sassafrinamine A (3), were isolated from the filamentous fungus Aspergillus neoglaber. The structures of the compounds were determined by nuclear magnetic resonance spectroscopy, ...