Investigation of the antimicrobial, antibiofilm, and immunomodulatory activities of cranberry (Vaccinium macrocarpon L.) proanthocyanidins against multidrug-resistant pathogens [0.03%]
蔓越莓原花青素对多重耐药病原体的抗菌、抗生物膜和免疫调节作用的研究
Mai Zafer,Omar Zayan,Rawan Nasser et al.
Mai Zafer et al.
The increasing emergence of multidrug-resistant (MDR) pathogens poses a significant challenge to global healthcare, necessitating the development of alternative antimicrobial strategies. In the present study, cranberry extract was evaluated...
Microbial functions in skin inflammation: a Mendelian randomization study [0.03%]
基于孟德尔随机化研究的皮肤炎症中微生物的功能作用
Yujie Yang,Yiyuan Zhong,Peng Wu et al.
Yujie Yang et al.
Inflammatory skin diseases (ISDs) represent a significant global health burden, yet the role of the human microbiome in their pathogenesis remains unclear. This study employed a comprehensive two-sample Mendelian randomization (MR) framewor...
Combination antifungal therapy against resistant C. albicans: efficacy and immune response in mice [0.03%]
抗药性白念珠菌的联合抗真菌治疗：小鼠的疗效和免疫反应
Ali Taghizadeh-Maleki,Farahnaz Hatami,Sima-Sadat Seyedjavadi et al.
Ali Taghizadeh-Maleki et al.
This study demonstrates the therapeutic effects of combination therapies against Candida albicans in mouse models, as opposed to mono-therapeutic treatments, while also comparing the pathogenicity of both sensitive and resistant strains. Fl...
Solid-state fermentation of tropical agro-industrial wastes using Pleurotus ostreatus for fungal protein production [0.03%]
利用平菇固态发酵热带农业废弃物生产真菌蛋白
Kingsley I Eneogwe
Kingsley I Eneogwe
Solid-state fermentation (SSF) of lignocellulosic agro-industrial wastes using white-rot fungi represents a scalable, low-energy strategy for converting underutilised tropical biomass into high-quality fungal protein. This study optimised s...
Preparation, characterization and application of feline CD3-specific single-domain antibodies [0.03%]
猫特异性CD3单区域抗体的制备、鉴定及应用研究
Jingjing Wang,Qihuan Zhao,Bo Wang et al.
Jingjing Wang et al.
Feline lymphoma, a prevalent feline malignancy, responds poorly to conventional chemotherapy-a setting that underscores the urgent need for targeted therapeutic alternatives. The stable expression of CD3 on T-cell lymphoma cells positions t...
Potential link between Gordonibacter pamelaeae and phospholipase C gamma 1 in osteoarthritis [0.03%]
葛氏杆菌与骨关节炎关系的潜在证据：对泛氏菌属中一种新种和磷脂酶Cγ1的研究
Shengkun Li,Shaozi Zhong,Chun Zeng
Shengkun Li
The gut-joint axis has been increasingly implicated in osteoarthritis (OA), yet the causal contribution of specific gut microbes and their downstream molecular mechanisms remain unclear. We employed a multi-stage, two-sample Mendelian rando...
Effect of single and combined nitrogen sources on lipid production by Rhodotorula kratochvilovae and Rhodotorula paludigena [0.03%]
单种和组合氮源对Rhodotorula kratochvilovae和Rhodotorula paludigena产脂的影响
Neveen Hassan Mansour,Ahmad Mohamad Moharram,Zeinab Soliman
Neveen Hassan Mansour
Oleaginous yeasts of the genus Rhodotorula are promising microbial platforms for sustainable lipid production. However, nitrogen availability critically regulates both biomass formation and lipid production, with nitrogen limitation recogni...
Hemoglobin expression reduces aerobic bioconversion of guaiacol in Pseudomonas putida despite non-limiting oxygen [0.03%]
血红蛋白表达降低了枯草色假单胞菌在非耗氧条件下丁香酚有氧生物转化效率
Fredrik Lund,Matilda Dellson,Nélida Leiva Eriksson et al.
Fredrik Lund et al.
Efficient lignin valorization relies on oxidative enzymatic reactions, making oxygen availability a critical determinant of process performance. Pseudomonas putida, an obligate aerobe and promising host for valorization of aromatic compound...
Exploratory analysis of genotoxic Escherichia coli and Helicobacter pylori virulence in gastrointestinal carcinogenesis [0.03%]
胃肠道癌症发生过程中致基因毒性的大肠杆菌和幽门螺旋杆菌毒力的探索性分析
Tayyip Karaman,Nesteren Mansur-Ozen,Arzu Tiftikçi et al.
Tayyip Karaman et al.
Gastrointestinal cancers remain among the leading causes of cancer-related mortality worldwide. Beyond environmental and hereditary determinants, increasing evidence suggests that the gut microbiota may contribute to carcinogenesis through ...
Open-mixed fermentative culture as a feasible strategy to valorize agroindustrial residues into lactic acid [0.03%]
开-混合发酵作为将农业工业残渣转化为乳酸的可行策略
A Martorell-Múgica,D Sánchez-Mata,C González-Fernández et al.
A Martorell-Múgica et al.
Lactic acid (HLact) is a platform chemical with wide industrial applications, and its production from waste streams offers a cost-effective alternative to conventional feedstock. However, pure bacterial cultures represent one of the highest...