A novel genotyping technique for discriminating LVAS-associated high-frequency variants in SLC26A4 gene [0.03%]
一种用于区分SLC26A4基因中与LVAS相关的高频变异的新型分型技术
Chen Zhou,Xiangman Zou,Cuiying Peng et al.
Chen Zhou et al.
An increasing number of biological and epidemiological evidence suggests that c.919-2A > G and c.2168A > G variants of solute carrier family 26, member 4 (SLC26A4) gene play a critical role in the development of large vestibular aqueduct sy...
Tabersonine ameliorates osteoblast apoptosis in rats with dexamethasone-induced osteoporosis by regulating the Nrf2/ROS/Bax signalling pathway [0.03%]
黄隐花碱通过调控Nrf2/ROS/Bax信号通路改善地塞米松诱导的骨质疏松大鼠的成骨细胞凋亡
Xi Sun,Lijun Gan,Nan Li et al.
Xi Sun et al.
We explored how tabersonine (Tab) protected against dexamethasone (Dex)-induced osteoporosis. Osteoblasts were treated with Dex (100 µM) with or without Table (5 or 10 µM). We measured cell viability, alkaline phosphatase (ALP) activity, ...
Jiping Shao,Debin Zeng,Shuhong Tian et al.
Jiping Shao et al.
Drugs targeting the fusion process of viral entry into host cells have been approved for clinical use in the treatment of AIDS. There remains a great need to improve the use of existing drugs for HIV therapy. Berberine is traditionally used...
Bacillus velezensis 83 a bacterial strain from mango phyllosphere, useful for biological control and plant growth promotion [0.03%]
来自芒果叶面的菌株Bacillus velezensis 83，可用于生物控制和促进植物生长
Karina A Balderas-Ruíz,Patricia Bustos,Rosa I Santamaria et al.
Karina A Balderas-Ruíz et al.
Bacillus velezensis 83 was isolated from mango tree phyllosphere of orchards located in El Rosario, Sinaloa, México. The assessment of this strain as BCA (biological control agent), as well as PGPB (plant growth-promoting bacteria), were d...
Origanum vulgare L. extract-mediated synthesis of silver nanoparticles, their characterization and antibacterial activities [0.03%]
牛至提取物介导的银纳米粒子的合成，表征及其抗菌活性
Syuzanna Hambardzumyan,Naira Sahakyan,Margarit Petrosyan et al.
Syuzanna Hambardzumyan et al.
Plant extracts serve as reducing and coating agents and are, therefore, commonly employed for the generation of silver (Ag) nanoparticles (NPs). Plant extract mediated synthesis of Ag NPs is a green, environmentally friendly and cost-effect...
Biosynthesis, characterization of PLGA coated folate-mediated multiple drug loaded copper oxide (CuO) nanoparticles and it's cytotoxicity on nasopharyngeal cancer cell lines [0.03%]
PLGA包覆的叶酸介导的多药负载氧化铜(CuO)纳米颗粒的生物合成，表征及其对鼻咽癌细胞系的细胞毒性的研究
Long-Mei Guo,Xue-Mei Xu,Dong Zhao et al.
Long-Mei Guo et al.
Cytotoxicity of CuO nanoparticles (NPs) are an impediment in utilizing them as an effective nanocarriers of chemotherapeutic drugs for targeted drug delivery in nasopharyngeal cancer. In our current study, we have designed a two-step synthe...
Molecular dynamics simulation and experimental study of the surface-display of SPA protein via Lpp-OmpA system for screening of IgG [0.03%]
通过Lpp-OmpA系统表面展示SPA蛋白筛选IgG的分子动力学模拟和实验研究
M Vahed,F Ramezani,V Tafakori et al.
M Vahed et al.
Staphylococcal protein A (SpA) is a major virulence factor of Staphylococcus aureus. S. aureus is able to escape detection by the immune system by the surface display of protein A. The SpA protein is broadly used to purify immunoglobulin G ...
Fermented Astragalus in diet improved laying performance, egg quality, antioxidant and immunological status and intestinal microbiota in laying hens [0.03%]
日粮中添加发酵黄芪对产蛋鸡产蛋性能、蛋品质、抗氧化和免疫状态及肠道微生物的影响
Hong-Tao Shi,Bai-Yu Wang,Chuan-Zhou Bian et al.
Hong-Tao Shi et al.
In the era of increased antibiotic resistance and ever-stricter control on antibiotic use, it is urgent to develop green, safe, and non-residue alternatives to antibiotics applied to the poultry industry. To this end, we supplied the potent...
Rhein laden pH-responsive polymeric nanoparticles for treatment of osteoarthritis [0.03%]
用于治疗骨关节炎的装载雷尼替丁的pH响应型聚酸纳米颗粒
Bo Hu,Feng Gao,Chunbao Li et al.
Bo Hu et al.
Osteoarthritis (OA) is a condition associated with severe inflammation, cartilage destruction and degeneration of joints. Rhein (Rh) is an effective anti-inflammatory drug with proven efficacy in in-vitro and in-vivo models. pH sensitive Rh...
Long non-coding RNA LINC00525 regulates the proliferation and epithelial to mesenchymal transition of human glioma cells by sponging miR-338-3p [0.03%]
长链非编码RNA LINC00525通过吸附miR-338-3p调节人脑胶质瘤细胞的增殖和上皮间充质转化
Yilv Wan,Feng Liang,Minjun Wei et al.
Yilv Wan et al.
Long non-coding RNA (LncRNA) LINC00525 has been shown to be upregulated in several human cancers and deduced to possess caner regulatory role. The regulation of molecular mechanics of human glioma by lncRNA-LINC00525 through microRNA spongi...