Exploratory gut microbiota-host interaction in parkinson's disease: integrative multi-omics analysis of metabolic and epigenetic pathways [0.03%]
整合多组学分析探索帕金森病的肠道微生物群宿主代谢和表观遗传途径之间的相互作用
Guangli Li,Xiaoping Ye,Tao Zhou et al.
Guangli Li et al.
Mounting evidence has associated gut microbial composition and systemic metabolic profiles with Parkinson's disease (PD), yet causal pathways and molecular mechanisms remain unclear. We employed a systematic two-stage analytical framework i...
Odoribacter laneus protects intestinal barrier by bile acid-FXR axis in acute pancreatitis [0.03%]
奥氏伯克霍尔德菌通过胆汁酸-FXR轴保护急性胰腺炎中的肠屏障功能
Ruru Gu,Jiazheng Li,Jinfeng Qi et al.
Ruru Gu et al.
Odoribacter laneus (O. laneus) is a promising probiotic. Acute pancreatitis (AP) is an acute abodominal disease accompanied by intestinal barrier dysfunction and gut dysbiosis. However, the effects of O. laneus in AP remain unexplored. We e...
Genomic and spectroscopic analysis for antimicrobial metabolite profiling of Microbacterium testaceum endophyte [0.03%]
基于基因组和光谱学的植生微杆菌抗菌代谢产物分析方法
Merihan S Sabra,Amr S Bishr,Lina Jamil M Abdel-Hafez et al.
Merihan S Sabra et al.
Wild plants harbor distinct endophytes that produce potent antimicrobial metabolites that can be used to combat life-threatening pathogens. In our study, four bacterial endophytes (LP1, LP2, LP3, LP4) were isolated from the inner tissues of...
In vitro nano‑emodin-associated exosome‑mediated aPDT against Acinetobacter baumannii [0.03%]
体外纳米埃姆多汀相关外泌体介导的蓝光光动力对耐药鲍曼不动杆菌的作用研究
Samane Teymouri,Hadiseh Mohammadpour,Maryam Pourhajibagher et al.
Samane Teymouri et al.
Biofilm-forming Acinetobacter baumannii, particularly multidrug-resistant (MDR) strains, present major challenges in burn wound treatment. This study evaluated the antibacterial and antibiofilm efficacy of exosomes associated with nano-emod...
Whole-genome analysis of Pantoea alfalfae HF1 isolated from shot hole lesions in peach leaves and symptom reproduction by wound inoculation [0.03%]
全基因组分析从桃树叶枪孔病斑分离的潘诺娃芽杆菌HF1及伤口接种再侵染症状
Yi-Run Wu,Xue Xu,Yan Hu et al.
Yi-Run Wu et al.
Bacterial leaf shot-hole disease has become an increasingly serious threat to peach production and related industries. Here, we isolated a bacterial strain, designated HF1, from symptomatic peach leaves infected with shot holes in Hefei Cit...
In vitro and in vivo antitumor activity of Laz-expressing Salmonella Typhimurium YB1 via optimized secretion and regulation [0.03%]
通过优化分泌和调控的Laz表达鼠伤寒沙门菌YB1的体内外抗肿瘤活性研究
Yahia I Abouelenen,Radwa M Ramzy,Alshaymaa Amin Zaki El-Bahy et al.
Yahia I Abouelenen et al.
Salmonella enterica serovar Typhimurium strain YB1 is a genetically engineered obligate anaerobe with strong tumor-targeting potential. In this study, we evaluated YB1 as a delivery platform for Laz, a lipidated azurin-derived protein, usin...
Analysis and application of microbiota in fermentation pit muds used for Chinese strong-flavor liquor production [0.03%]
发酵泥浆中微生物群落分析及其应用研究进展
Hong Dong,Qingyi Fu,Qingyang Wan et al.
Hong Dong et al.
Chinese strong-flavor liquor (CSFL), the primary type of Chinese liquor in terms of both production and sales, is produced through complex fermentation in pits covered with fermentation pit mud (FPM). FPM, which contains complex microbiota,...
Microbial assembly and metabolic restructuring following CO2 injection in subsurface oil reservoir [0.03%]
二氧化碳注入后次表生油藏中的微生物组装及代谢重构
Le-Gang Chen,Lei Zhou,Bo-Wen Wang et al.
Le-Gang Chen et al.
Carbon dioxide (CO2) injection into oil reservoirs is a well-established and promising strategy for enhancing oil recovery while simultaneously sequestering carbon, whose effectiveness is increasingly recognized to be influenced by microbia...
Antibiotic resistance among Gram-negative bacteria in bloodstream infections in Shiraz, Iran (2012-2023) [0.03%]
伊朗设拉子（2012-2023）血流感染中革兰氏阴性菌的抗生素耐药性分析
Mohammad Hossein Nejati Boor Boor,Sahar Sabour,Hadi Ghasemi et al.
Mohammad Hossein Nejati Boor Boor et al.
Regular monitoring and conducting surveillance studies are necessary to control and treat antibiotic-resistant infections on a global scale. The present study aimed to perform a time-trend analysis of the distribution and antibiotic resista...
Effects of dietary zinc fulvate supplementation on egg quality, serum biochemical indices, and intestinal health of aged laying hens [0.03%]
饲喂植物蒸馏富锌液对蛋鸡产蛋后期鸡蛋品质、血清生化指标和肠道健康的影响
Kai Guo,Yanling Feng,Genwang Xu et al.
Kai Guo et al.
Zinc fulvate (ZFA), a chelate of fulvic acid and zinc, exhibits superior bioavailability and multifunctional properties that benefit animal health. This study aimed to evaluate the effects of dietary ZFA supplementation at different levels ...