Cerebral autoregulation, spreading depolarization, and implications for targeted therapy in brain injury and ischemia [0.03%]
脑自主调节、扩散去极化与脑损伤和缺血的靶向治疗 implication
Andrew P Carlson,Andrew R Mayer,Chad Cole et al.
Andrew P Carlson et al.
Cerebral autoregulation is an intrinsic myogenic response of cerebral vasculature that allows for preservation of stable cerebral blood flow levels in response to changing systemic blood pressure. It is effective across a broad range of blo...
Payam Shahsavar,Sepideh Ghazvineh,Mohammad Reza Raoufy
Payam Shahsavar
While breathing is a vital, involuntary physiological function, the mode of respiration, particularly nasal breathing, exerts a profound influence on brain activity and cognitive processes. This review synthesizes existing research on the i...
Methylene blue and its potential in the treatment of traumatic brain injury, brain ischemia, and Alzheimer's disease [0.03%]
亚甲蓝及其在创伤性脑损伤、脑缺血和阿尔茨海默病治疗中的潜在作用
Nickolay K Isaev,Elizaveta E Genrikhs,Elena V Stelmashook
Nickolay K Isaev
Traumatic brain injury (TBI) and brain ischemia/reperfusion cause neurodegenerative processes that can continue after the acute stage with the development of severe brain atrophy with dementia. In this case, the long-term neurodegeneration ...
Shoushuai Wang,Xinggui Wen,Zheyuan Fan et al.
Shoushuai Wang et al.
Peripheral nerve injury (PNI) is one of the most serious causes of disability and loss of work capacity of younger individuals. Although PNS has a certain degree of regeneration, there are still challenges like disordered growth, neuroma fo...
Impact of carotid stenosis on the outcome of stroke patients submitted to reperfusion treatments: a narrative review [0.03%]
颈动脉狭窄对接受再灌注治疗的卒中患者预后的影响：叙事综述
Giovanna Viticchi,Lorenzo Falsetti,Claudia Altamura et al.
Giovanna Viticchi et al.
Intravenous thrombolysis (IT) and mechanical thrombectomy (MD) are the two interventional approaches that have changed the outcome of patients with acute ischemic stroke (AIS). Ipsilateral and contralateral carotid stenosis (ICS, CCS) play ...
Darya Rajabi,Shaghayegh Khanmohammadi,Nima Rezaei
Darya Rajabi
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with a poor prognosis leading to death. The diagnosis and treatment of ALS are inherently challenging due to its complex pathomechanism. Long noncoding RNAs (lnc...
Dendritic spines and their role in the pathogenesis of neurodevelopmental and neurological disorders [0.03%]
树突棘及其在神经发育和神经系统障碍发病机理中的作用
Aisan Akhgari,Tanja Maria Michel,Manouchehr Seyedi Vafaee
Aisan Akhgari
Since Cajal introduced dendritic spines in the 19th century, they have attained considerable attention, especially in neuropsychiatric and neurologic disorders. Multiple roles of dendritic spine malfunction and pathology in the progression ...
Analysis of radiological features in patients with post-stroke depression and cognitive impairment [0.03%]
卒中后抑郁和认知障碍患者的影像学特征分析
Jun Mu,Jiayi Li
Jun Mu
Post-stroke depression (PSD) and post-stroke cognitive impairment (PSCI) are common complications following a stroke, significantly impacting the quality of life and survival time of survivors. Currently, the comorbidity of PSCI and PSD is ...
Current potential pathogenic mechanisms of copper-zinc superoxide dismutase 1 (SOD1) in amyotrophic lateral sclerosis [0.03%]
铜锌超氧化物歧化酶1(SOD1)在肌萎缩侧索硬化症中的潜在致病机制研究进展
Xin-Xin Wang,Wen-Zhi Chen,Cheng Li et al.
Xin-Xin Wang et al.
Amyotrophic lateral sclerosis (ALS) is a rare neurodegenerative disease which damages upper and lower motor neurons (UMN and LMN) innervating the muscles of the trunk, extremities, head, neck and face in cerebrum, brain stem and spinal cord...
Haym Benaroya
Haym Benaroya
An extensive review is presented on mitochondrial structure and function, mitochondrial proteins, the outer and inner membranes, cristae, the role of F1FO-ATP synthase, the mitochondrial contact site and cristae organizing system (MICOS), t...