Remote ischemic conditioning for acute ischemic stroke: dawn in the darkness [0.03%]
急性缺血性卒中的远程缺血预适应:拨开黑暗的曙光
Jingrui Pan,Xiangpen Li,Ying Peng
Jingrui Pan
Stroke is a leading cause of disability with high morbidity and mortality worldwide. Of all strokes, 87% are ischemic. The only approved treatments for acute ischemic stroke are intravenous thrombolysis with alteplase within 4.5 h and throm...
Recent progress on the role of GABAergic neurotransmission in the pathogenesis of Alzheimer's disease [0.03%]
近年关于GABA能神经传递在阿尔茨海默病病理发生发展中作用的研究进展
Ghulam Abbas,Wajahat Mahmood,Nurul Kabir
Ghulam Abbas
Despite their possible causative role, targeting amyloidosis, tau phosphorylation, acetylcholine esterase, glutamate, oxidative stress and mitochondrial metabolism have not yet led to the development of drugs to cure Alzheimer's disease (AD...
Emotion regulation strategies in trauma-related disorders: pathways linking neurobiology and clinical manifestations [0.03%]
创伤相关障碍中的情绪调节策略:神经生物学与临床表现之间的联系路径研究
Lucía Del Río-Casanova,Anabel González,Mario Páramo et al.
Lucía Del Río-Casanova et al.
Emotion regulation impairments with traumatic origins have mainly been studied from posttraumatic stress disorder (PTSD) models by studying cases of adult onset and single-incident trauma exposure. The effects of adverse traumatic experienc...
Cognitive function in schizophrenia: conflicting findings and future directions [0.03%]
精神分裂症的认知功能:矛盾的发现及未来方向
Ahmed A Moustafa,Julia K Garami,Justin Mahlberg et al.
Ahmed A Moustafa et al.
Introduction: Schizophrenia is a severe mental disorder with multiple psychopathological domains being affected. Several lines of evidence indicate that cognitive impairment serves as the key component of schizophrenia ps...
The mental time travel continuum: on the architecture, capacity, versatility and extension of the mental bridge into the past and future [0.03%]
贯穿过去与未来的心理时间旅行连续体:关于心理桥梁的结构、容量、灵活度及拓展性
Prescott Breeden,Dorothea Dere,Armin Zlomuzica et al.
Prescott Breeden et al.
Mental time travel (MTT) is the ability to remember past events and to anticipate or imagine events in the future. MTT globally serves to optimize decision-making processes, improve problem-solving capabilities and prepare for future needs....
The multi-facet aspects of cell sentience and their relevance for the integrative brain actions: role of membrane protein energy landscape [0.03%]
细胞觉醒的多面性及其对整合脑功能的作用:膜蛋白能量景观的作用
Luigi F Agnati,Manuela Marcoli,Guido Maura et al.
Luigi F Agnati et al.
Several ion channels can be randomly and spontaneously in an open state, allowing the exchange of ion fluxes between extracellular and intracellular environments. We propose that the random changes in the state of ion channels could be also...
Chronic stress, hippocampus and parvalbumin-positive interneurons: what do we know so far? [0.03%]
慢性压力、海马和 parvalbumin阳性中间神经元:迄今为止我们知道了什么?
Ivan Zaletel,Dragana Filipović,Nela Puškaš
Ivan Zaletel
The hippocampus is a brain structure involved in the regulation of hypothalamic-pituitary-adrenal (HPA) axis and stress response. It plays an important role in the formation of declarative, spatial and contextual memory, as well as in the p...
Endogenous spontaneous ultraweak photon emission in the formation of eye-specific retinogeniculate projections before birth [0.03%]
产前眼特异性视网膜丘脑投射形成的内源性超弱发光现象
István Bókkon,Felix Scholkmann,Vahid Salari et al.
István Bókkon et al.
In 1963, it was suggested [Sperry, R.W. (1963). Chemoaffinity in the orderly growth of nerve fiber patterns and connections. Proc. Natl. Acad. Sci. USA 50, 703-710.] that molecular cues can direct the development of orderly connections betw...
The difference between electrical microstimulation and direct electrical stimulation - towards new opportunities for innovative functional brain mapping? [0.03%]
电微刺激与直接电刺激的区别——创新功能脑图谱研究的新机遇?
Marion Vincent,Olivier Rossel,Mitsuhiro Hayashibe et al.
Marion Vincent et al.
Both electrical microstimulation (EMS) and direct electrical stimulation (DES) of the brain are used to perform functional brain mapping. EMS is applied to animal fundamental neuroscience experiments, whereas DES is performed in the operati...
Current advances in cell electrophysiology: applications for the analysis of intercellular communications within the neurovascular unit [0.03%]
细胞电生理的最新进展:在神经血管单元间细胞通讯分析中的应用
Anton N Shuvaev,Vladimir V Salmin,Natalia V Kuvacheva et al.
Anton N Shuvaev et al.
Patch clamp is a golden standard for studying (patho)physiological processes affecting membranes of excitable cells. This method is rather labor-intensive and requires well-trained professionals and long-lasting experimental procedures; the...