Dysfunctional microglia and tau pathology in Alzheimer's disease [0.03%]
阿尔茨海默病中功能失调的小胶质细胞与tau蛋白病理变化的关系
Gunel Ayyubova
Gunel Ayyubova
Extensive human studies and animal models show that chronic immune system stimulation involving microglia, inflammasome, complement activation, synthesis of cytokines, and reactive oxygen species exacerbates neurodegeneration in Alzheimer's...
A systematic review of the effect of photobiomodulation on the neuroinflammatory response in animal models of neurodegenerative diseases [0.03%]
光生物调节对神经退行性疾病动物模型中神经炎症反应影响的系统性综述
Kangzhe Xie,Hala El Khoury,John Mitrofanis et al.
Kangzhe Xie et al.
This systematic review examines the effect of photobiomodulation (PBM), the application of red to near infrared light on body tissues, on the neuroinflammatory response and oxidative stress in animal models of neurodegenerative diseases. Th...
Brain circuit pathology in Down syndrome: from neurons to neural networks [0.03%]
唐氏综合征的脑回路病理学：从神经元到神经网络
Renata Bartesaghi
Renata Bartesaghi
Down syndrome (DS), a genetic pathology caused by triplication of chromosome 21, is characterized by brain hypotrophy and impairment of cognition starting from infancy. While studies in mouse models of DS have elucidated the major neuroanat...
A meta-analytical review of transcranial direct current stimulation parameters on upper limb motor learning in healthy older adults and people with Parkinson's disease [0.03%]
健康老年人和帕金森病患者上肢运动学习的经颅直流电刺激参数的荟萃分析回顾
Jessie Siew-Pin Leuk,Kai-En Yow,Clenyce Zi-Xin Tan et al.
Jessie Siew-Pin Leuk et al.
Current literature lacks consolidated evidence for the impact of stimulation parameters on the effects of transcranial direct current stimulation (tDCS) in enhancing upper limb motor learning. Hence, we aim to synthesise available methodolo...
Neural correlates of multisensory integration in the human brain: an ALE meta-analysis [0.03%]
基于人脑的多感觉整合神经相关性：ALE元分析研究
Sebastian Scheliga,Thilo Kellermann,Angelika Lampert et al.
Sebastian Scheliga et al.
Previous fMRI research identified superior temporal sulcus as central integration area for audiovisual stimuli. However, less is known about a general multisensory integration network across senses. Therefore, we conducted activation likeli...
Molecular mediators of angiogenesis and neurogenesis after ischemic stroke [0.03%]
缺血性脑卒中后血管发生和神经发生的分子介质
Mitch R Paro,Arijit R Chakraborty,Sophia Angelo et al.
Mitch R Paro et al.
The mechanisms governing neurological and functional recovery after ischemic stroke are incompletely understood. Recent advances in knowledge of intrinsic repair processes of the CNS have so far translated into minimal improvement in outcom...
Dual-site TMS as a tool to probe effective interactions within the motor network: a review [0.03%]
双位点经颅磁刺激作为探究运动网络内部有效相互作用的工具：综述
Shanti Van Malderen,Melina Hehl,Stefanie Verstraelen et al.
Shanti Van Malderen et al.
Dual-site transcranial magnetic stimulation (ds-TMS) is well suited to investigate the causal effect of distant brain regions on the primary motor cortex, both at rest and during motor performance and learning. However, given the broad set ...
Paulina Śledzińska,Marek Bebyn,Jacek Furtak et al.
Paulina Śledzińska et al.
Gliomas are the most common primary central nervous system tumors; despite recent advances in diagnosis and treatment, glioma patients generally have a poor prognosis. Hence there is a clear need for improved therapeutic options. In recent ...
Mitochondrial fission mediated by Drp1-Fis1 pathway and neurodegenerative diseases [0.03%]
Drp1-Fis1介导的线粒体分裂与神经退行性疾病的关系
Wenjia Shi,Cheng Tan,Can Liu et al.
Wenjia Shi et al.
In recent years, the role of mitochondrial dynamics in neurodegenerative diseases has becoming increasingly important. More and more evidences have shown that in pathological conditions, abnormal mitochondrial divisions, especially Drp1-Fis...
The limitations of investigating appetite through circuit manipulations: are we biting off more than we can chew? [0.03%]
通过回路操控研究摄食的局限性：我们承接的任务太多了吗？
Joshua Wang,Kate Beecher,Fatemeh Chehrehasa et al.
Joshua Wang et al.
Disordered eating can underpin a number of debilitating and prevalent chronic diseases, such as obesity. Broader advances in psychopharmacology and biology have motivated some neuroscientists to address diet-induced obesity through reductio...