Two-photon microscopy: application advantages and latest progress for in vivo imaging of neurons and blood vessels after ischemic stroke [0.03%]
双光子显微镜在缺血性脑卒中后的神经元和血管原位成像中的应用优势及最新进展
Jiarui Li,Xuan Wu,Yu Fu et al.
Jiarui Li et al.
Two-photon microscopy (TPM) plays an important role in the study of the changes of the two important components of neurovascular units (NVU) - neurons and blood vessels after ischemic stroke (IS). IS refers to sudden neurological dysfunctio...
Targeting NMDA receptor signaling for therapeutic intervention in brain disorders [0.03%]
针对脑部疾病治疗的NMDA受体信号通路干预
He Chen,Yuanping Dong,Yun Wu et al.
He Chen et al.
N-Methyl-d-aspartate (NMDA) receptor hyperfunction plays a key role in the pathological processes of depression and neurodegenerative diseases, whereas NMDA receptor hypofunction is implicated in schizophrenia. Considerable efforts have bee...
Anticipatory attractors, functional neurochemistry and "Throw & Catch" mechanisms as illustrations of constructivism [0.03%]
预期吸引子，功能神经化学和“投掷与接球”机制作为建构主义的说明
Irina Trofimova
Irina Trofimova
This review explores several rarely discussed examples illustrating constructivism principles, generative and selective features of neuronal regulation of behaviour. First, the review highlights Walter Freeman's experiments and mathematical...
Lan Yang,Jianfei Nao
Lan Yang
The most prevalent dementia-causing neurodegenerative condition is Alzheimer's disease (AD). The aberrant buildup of amyloid β and tau hyperphosphorylation are the two most well-known theories about the mechanisms underlying AD development...
Current advances in stem cell therapy in the treatment of multiple sclerosis [0.03%]
干细胞治疗多发性硬化症的最新进展
Parnian Zolfaghari Baghbadorani,Amirmasoud Rayati Damavandi,Samira Moradi et al.
Parnian Zolfaghari Baghbadorani et al.
Multiple sclerosis (MS) is an inflammatory disease related to the central nervous system (CNS) with a significant global burden. In this illness, the immune system plays an essential role in its pathophysiology and progression. The currentl...
Recent research progress on metabolic syndrome and risk of Parkinson's disease [0.03%]
代谢综合征与帕金森病发病风险的近期研究进展
Lin-Yi Li,Shu-Fen Liu,Jian-Long Zhuang et al.
Lin-Yi Li et al.
Parkinson's disease (PD) is one of the most widespread neurodegenerative diseases. PD is associated with progressive loss of substantia nigra dopaminergic neurons, including various motor symptoms (e.g., bradykinesia, rigidity, and resting ...
Extracellular histones as damage-associated molecular patterns in neuroinflammatory responses [0.03%]
神经炎症反应中与细胞外组蛋白相关的分子模式损伤
Christy M Richards,Seamus A McRae,Athena L Ranger et al.
Christy M Richards et al.
The four core histones H2A, H2B, H3, H4, and the linker histone H1 primarily bind DNA and regulate gene expression within the nucleus. Evidence collected mainly from the peripheral tissues illustrates that histones can be released into the ...
An update to pain management after spinal cord injury: from pharmacology to circRNAs [0.03%]
脊髓损伤后的疼痛管理更新：从药理学到环状RNA
Graciela L Mazzone,María F Coronel,Miranda Mladinic et al.
Graciela L Mazzone et al.
Neuropathic pain (NP) following a spinal cord injury (SCI) is often hard to control and therapies should be focused on the physical, psychological, behavioral, social, and environmental factors that may contribute to chronic sensory symptom...
Simulation of oscillatory dynamics induced by an approximation of grid cell output [0.03%]
基于网格细胞信号近似的振荡动力学模拟
Roger D Traub,Miles A Whittington,Mark O Cunningham
Roger D Traub
Grid cells, in entorhinal cortex (EC) and related structures, signal animal location relative to hexagonal tilings of 2D space. A number of modeling papers have addressed the question of how grid firing behaviors emerge using (for example) ...
A systematic review of transcranial direct current stimulation on eye movements and associated psychological function [0.03%]
经颅直流电刺激对眼动及其相关心理功能的系统综述
Ashwin Subramaniam,Sicong Liu,Liam Lochhead et al.
Ashwin Subramaniam et al.
The last decades have seen a rise in the use of transcranial direct current stimulation (tDCS) approaches to modulate brain activity and associated behavior. Concurrently, eye tracking (ET) technology has improved to allow more precise quan...