Skeletal Muscle and Circulating microRNAs Adaptations to 12-Week HIIT With or Without L-Citrulline in Obese Older Adults [0.03%]
肥胖老年人12周高强度间歇训练联合或不联合L-瓜氨酸对骨骼肌和循环微小RNA的调节作用
Alexandre Mercier-Guery,Marjorie Millet,Martine Croset et al.
Alexandre Mercier-Guery et al.
Background: High-intensity interval training (HIIT) with or without L-citrulline (CIT) oral supplementation improves body composition, functional capacities and muscle health in obese older adults, potentially through mic...
Randomized Controlled Trial
Journal of cachexia, sarcopenia and muscle. 2026 Apr;17(2):e70267. DOI:10.1002/jcsm.70267 2026
Automated CT-Based Muscle Density Predicts Mortality Regardless of Muscle Area [0.03%]
基于自动化的CT肌肉密度预测死亡率，而不考虑肌肉面积的影响
Adam J Kuchnia,Glen M Blake,Matthew H Lee et al.
Adam J Kuchnia et al.
Background: Abdominal CT-based assessments of skeletal muscle may provide important prognostic information for all-cause mortality in aging adults. We aimed to evaluate whether AI-segmented muscle area and muscle density ...
Feeding Behaviour in the KPC Model of Pancreatic Cancer-Associated Cachexia: Alteration of Spontaneous and Evoked Feeding Behaviours [0.03%]
KPC模型中胰腺癌相关恶病质的摄食行为：自发性和诱发性摄食行为的变化
Fateema Muzaffar,William F Colmers,Vickie E Baracos
Fateema Muzaffar
Background: The KPC mouse model of pancreatic cancer is gaining use in research, but detailed understanding of ingestive behaviour changes in this and other cachexia models is limited. ...
Hip Abductor Strength Predicts Injurious Falls and Mediates the Balance Confidence-Falls Relationship: A Competing Risk Model [0.03%]
臀中肌力量预测损伤性跌倒并介导平衡信心-跌倒关系：一种竞争风险模型
Tewodros Yosef,Julie A Pasco,Monica C Tembo et al.
Tewodros Yosef et al.
Background: Falls are a major public health issue, largely driven by age-related declines in hip and lower limb muscle strength. Hip muscle strength plays a critical role in postural stability and falls prevention. Lower ...
Fibro-Adipogenic Progenitors Regulate Orofacial Neuromuscular Junction Regeneration via Myostatin [0.03%]
纤维脂肪前体细胞通过肌抑素调节头面部神经肌肉接头的再生
Ruizhi Li,Ruojing Liu,Yixuan Huang et al.
Ruizhi Li et al.
Background: Orofacial and limb muscles differ in embryonic origin and regenerative capacity. Neuromuscular junction (NMJ) regeneration is critical for muscle restoration both histologically and functionally. The relative ...
KARIs, Ghrelin Receptor Agonists With Excellent Brain Permeability, Increase Food Intake and Attenuate the Muscle Loss in Mice [0.03%]
具有优异脑渗透性的胃抑制多肽受体激动剂(KARIs)可增加摄食并缓解小鼠肌肉损失
Hee Ji Yoon,Wan Hui Han,Sang Bo Kim et al.
Hee Ji Yoon et al.
Background: Ghrelin regulates appetite, gastrointestinal motility and growth hormone (GH) secretion through activation of the growth hormone secretagogue receptor (GHSR-1a) in hypothalamic neurons, with downstream effects...
Elevated Kallistatin Induces Myosteatosis and Exercise Intolerance by Antagonizing AdipoR1-Mediated AMPK Signalling [0.03%]
KLKS升高通过拮抗AdipoR1-AMPK信号诱导肌肉脂化和运动不耐受
Fuyan Hong,Zhenzhen Fang,Gang Shen et al.
Fuyan Hong et al.
Background: Pathological intramuscular lipid deposition (myosteatosis) and exercise intolerance are hallmarks of metabolic disorders, including diabetes and metabolic dysfunction-associated steatotic liver disease (MASLD)...
Longitudinal Deterioration in Nutritional Status Associated With Increased Risk of Sarcopenia in Community-Dwelling Aged Adults: A Prospective Cohort Study [0.03%]
营养状况纵向恶化与社区居住老年人 sarcopenia 发病风险增加有关：一项前瞻性队列研究
Ho Jun Lim,Seung Shin Park,Mi Ji Kim et al.
Ho Jun Lim et al.
Background: The association between changes in nutritional status over time and the risk of sarcopenia in older adults is unclear. This study investigated the impact of baseline nutritional status and its 4-year changes o...
Multicenter Study
Journal of cachexia, sarcopenia and muscle. 2026 Apr;17(2):e70270. DOI:10.1002/jcsm.70270 2026
Higher Grip Strength Is Associated With Reduced Risk of Incident Symptomatic Hand Osteoarthritis: Data From Two Cohort Studies [0.03%]
握力较强者膝关节外伤性关节炎的发病风险较低：来自两项队列研究的数据分析
Yilun Wang,Wei Li,Hongyi He et al.
Yilun Wang et al.
Background: Grip strength is increasingly recognized as a modifiable and easily measurable protective factor against chronic diseases. Lower grip strength may compromise joint stability, predisposing periarticular tissues...
Underweight Status Amplifies Respiratory Infection Mortality in Diabetes: Findings From a Nationwide Cohort Study [0.03%]
体重过低通过全国队列研究放大糖尿病患者的呼吸道感染死亡风险
Hun Jee Choe,Kyong Do Han,Ji-Hong Park et al.
Hun Jee Choe et al.
Background: Diabetes increases susceptibility to infectious respiratory diseases, but the impact of underweight status on mortality from these conditions remains unclear. We evaluated the association between low body mass...