Diagnostic Utility of Muscle Ultrasound for Sarcopenia in Prader-Willi Syndrome: A Cross-Sectional Study [0.03%]
普拉德-威利综合征 sarcopenia 诊断的肌肉超声检查作用：横断面研究
Luo-Hua Yu,Hsin-Chi Wu,I-Shiang Tzeng et al.
Luo-Hua Yu et al.
Background: Prader-Willi syndrome (PWS) is characterized by sarcopenic obesity; however, validated screening tools for muscle mass in clinical settings are lacking. This study aimed to evaluate the diagnostic utility of m...
Lowered Abundance of Gut Bacteriophage Species Is Associated With Human Cancer Cachexia [0.03%]
肠道噬菌体丰度降低与人类癌症恶病质相关联
Axel Stang,Thomas Illig,Karsten Hiller et al.
Axel Stang et al.
Background: Cancer cachexia exemplifies a high medical need condition without effective treatment. Recent studies implicated bacterial gut microbiome alterations to cancer cachexia. Whether the gut bacteriophage profile, ...
Muscle-Adipose Aging Dynamics and Inflammaging Patterns Across Ethnically Diverse Populations: Exploring Potential Roles of Lipolysis [0.03%]
跨种族人群肌少脂肪衰老动态及炎性老化模式的探索：脂解作用的潜在作用探讨
Fei-Yuan Hsiao,Jamie Chi-Yun Wu,I-Tzu Chen et al.
Fei-Yuan Hsiao et al.
Background: Muscle-adipose aging reflects interactions between body composition changes and chronic inflammatory processes, but age-related patterns in these measures across ethnically diverse populations remain incomplet...
Longitudinal Assessment of Muscle Involvement in Late-Onset Pompe Disease Using Quantitative MRI: A Prospective Cohort Study [0.03%]
定量磁共振成像纵向评估晚发型庞贝病的肌肉受累情况：前瞻性队列研究
Alice De Lorenzo,Johannes Forsting,Martijn Froeling et al.
Alice De Lorenzo et al.
Background: Late-onset Pompe disease (LOPD) is a progressive metabolic myopathy characterised by lysosomal glycogen accumulation and leading to secondary disruptions in autophagy and cellular energy metabolism. While enzy...
Novel Long-Acting Ghrelin Analogue PEP-064 Restores Energy Balance in C26 and Lewis Lung Carcinoma-Induced cachexia in Mice [0.03%]
新型长效ghrelin类似物PEP-064可恢复C26和Lewis肺癌诱导的小鼠恶病质的能耗平衡
J E Hunt,C Lund,B Chen et al.
J E Hunt et al.
Background: Cancer cachexia is a debilitating syndrome marked by involuntary weight loss resulting from reduced food intake and intricate metabolic reprogramming. Despite its high prevalence, cancer cachexia remains under...
Sema4A Protects Against Muscle Atrophy and Promotes Repair by Regulating Intracellular Metabolic Signalling [0.03%]
Sema4A通过调节细胞内代谢信号保护肌肉免受萎缩并促进修复
Caiyun Wang,Honghong Chen,Lingjie Shen et al.
Caiyun Wang et al.
Background: Skeletal muscle atrophy is a debilitating condition associated with diverse diseases and clinical interventions. Although triggers such as glucocorticoid excess or direct muscle injury disrupt the balance betw...
Handgrip Strength Thresholds to Detect Cardiometabolic Risk in Youth: Cross-Sectional Study and Meta-Analysis [0.03%]
基于横断面研究和荟萃分析的青少年心代谢风险检测的握力阈值标准的研究
Antonio García-Hermoso,Rodrigo Yáñez-Sepúlveda,Ignacio Hormazábal-Aguayo et al.
Antonio García-Hermoso et al.
Background: Muscular fitness, particularly handgrip strength, is increasingly recognized as a robust marker of cardiometabolic risk (CMR) in children and adolescents. However, evidence-based diagnostic thresholds for iden...
Combined Bisoprolol and Megestrol Acetate Improves Survival and Preserves Cardiac Performance in a Rat Model of Cancer Cachexia [0.03%]
美托洛尔联合甲地孕酮可改善癌症恶病质大鼠模型的生存率并维持心脏功能
Zihao Chen,Siqi Wang,Sandra Palus et al.
Zihao Chen et al.
Background: Cancer cachexia is associated with rapid body wasting and cardiac dysfunction. Bisoprolol (BIS) and megestrol acetate (MA) improve selected cachexia phenotypes in the Yoshida AH-130 model, but their combined e...
From Pixels to Prediction: Reviewing the Role of Artificial Intelligence in Body Composition Analysis [0.03%]
从像素到预测：人工智能在身体成分分析中的作用综述
Marta Zerunian,Benedetta Masci,Stefano Nardacci et al.
Marta Zerunian et al.
Evaluation of body composition (BC) is a set of biomarkers, including fat, muscle and bone, that allows the quantification of an individual's composition at different levels of complexity (whole body, tissues, macroscopic and microscopic). ...
Frailty Transforms Care Continuity-Mortality Relationships Across Age Groups: Evidence From Taiwan and South Korea [0.03%]
衰弱会根据年龄层转变护理连续性与死亡率之间的关系：来自台湾和韩国的证据
Fei-Yuan Hsiao,Sunyoung Kim,Lin-Chieh Meng et al.
Fei-Yuan Hsiao et al.
Background: Healthcare fragmentation typically predicts poor outcomes, yet its relationship with frailty across different age groups remains unexplored. We examined how frailty modifies the association between care patter...