Synergistic effect of Aloe Vera hydrogels with imatinib for pH-responsive drug release in breast cancer treatment [0.03%]
用于乳腺癌治疗的Aloe Vera水凝胶与伊马替尼的pH响应药物释放的协同作用
Aroob Hasan Khan,Adeeb Shehzad,Paola Pirela et al.
Aroob Hasan Khan et al.
Imatinib (IM) efficacy as a cancer drug is limited by pharmacokinetic drug resistance developed during systemic circulation before reaching the target site.Hydrogels have attracted attention because of their characteristic physiochemical an...
Exploring the impact of various zwitterionic surface modifications on the mucus diffusion and membrane permeability of lipid-based nanocarriers [0.03%]
探讨各种两性离子表面修饰对基于脂质纳米载体黏液渗透性和膜通透性的影响
Antonio Spennacchio,Luca Maurice Richter,Daniel Stengel et al.
Antonio Spennacchio et al.
This study investigates the effect of structural differences among six zwitterionic surfactants on the performance of lipid-based nanoemulsions. Nanoemulsions were prepared using a standardized formulation approach to minimize compositional...
Photothermal and pH-stimuli-responsive mesoporous silica nanoparticles drug delivery system for targeting the tumor cells [0.03%]
一种用于靶向肿瘤细胞的光热和pH刺激响应型介孔二氧化硅纳米粒子药物递送系统
Qi Chen,Zhengxi Wu,Yingying Ji et al.
Qi Chen et al.
To improve the precision of cancer therapy, multi-stimuli responsiveness and targeted, controllable drug release are essential components. In this study, we designed an intelligent drug delivery system that integrates chemotherapy and photo...
Impact of sodium caprate dosed as a mini-tablet or suspension on insulin delivery and mucosa histomorphology [0.03%]
作为迷你片剂或悬浮液给药的月桂醇对胰岛素传递和粘膜组织形态学的影响
Freja Fredholt,Joanne Heade,Jukka Rantanen et al.
Freja Fredholt et al.
A virtual factory for topical formulations based on molecular modeling and drug-polymer interaction studies [0.03%]
基于分子模拟和药物聚合物相互作用研究的局部给药制剂虚拟工厂
Harshvardhan Modh,Ayça Altay Benetti,Abu Zayed Badruddoza et al.
Harshvardhan Modh et al.
Topical drug delivery offers a cost-effective and non-invasive alternative to systemic drug administration but faces challenges due to the skin's barrier properties and the complex rheology of semisolid formulations. This necessitates a dee...
Advanced lipid-based niosomes for enhanced transdermal delivery of olmesartan medoxomil via intracutaneous drug depot: a novel biomimicry approach [0.03%]
一种新型仿生方法：通过皮下药物储库经皮给药的高级脂质基niosome递送奥美沙坦酯
Shahinaze A Fouad,Mostafa I Gebril,Fathy I Abd Allah et al.
Shahinaze A Fouad et al.
Olmesartan medoxomil (OMN), a highly selective antihypertensive agent but, with problematic oral delivery due to its low solubility and limited bioavailability. Therefore, biomimetic lipid-based niosomes were adopted as a novel approach to ...
Publisher Correction: Inhaled biologics for respiratory diseases: clinical potential and emerging technologies [0.03%]
出版更正：呼吸系统疾病的吸入生物制剂：临床潜力和新兴技术
Nur Adania Shaibie,Nur Dini Fatini Mohammad Faizal,Fhataheya Buang et al.
Nur Adania Shaibie et al.
Published Erratum
Drug delivery and translational research. 2025 Sep 27. DOI:10.1007/s13346-025-01985-8 2025
Clinically translatable anti-fibrotic nanosuspension for inhaled treatment of idiopathic pulmonary fibrosis [0.03%]
一种用于特发性肺纤维化吸入治疗的抗纤维化纳米混悬液及其临床转化研究
Daiheon Lee,Byoungjae Kong,Gijung Kwak et al.
Daiheon Lee et al.
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease characterized by chronic pulmonary fibrosis, irreversible lung function decline, and high mortality rate. Oral nintedanib (NTB) is one of the rare anti-fibrotic ...
Correction: Dual phage-incorporated electrospun polyvinyl alcohol-eudragit nanofiber matrix for rapid healing of diabetic wound infected by Pseudomonas aeruginosa and Staphylococcus aureus [0.03%]
题图纠正：用于快速修复由铜绿假单胞菌和金黄色葡萄球菌感染的糖尿病伤口的双重噬菌体包覆电纺聚乙烯醇-尤特拓利特纳米纤维基质
Kokkarambath Vannadil Suchithra,Asif Hameed,Suprith Surya et al.
Kokkarambath Vannadil Suchithra et al.
Published Erratum
Drug delivery and translational research. 2025 Sep 23. DOI:10.1007/s13346-025-01979-6 2025
Vacuum compression-molded polyvinyl alcohol microneedles for sustained three-day transdermal delivery of palonosetron hydrochloride [0.03%]
用于三天持续经皮递送帕洛诺司琼盐酸盐的聚乙烯醇微针
Meheli Ghosh,Sharvari M Kshirsagar,Thomas Kipping et al.
Meheli Ghosh et al.
This study introduces vacuum compression molding (VCM) as a novel, solvent-free method for fabricating palonosetron hydrochloride (PAL HCl)-loaded polyvinyl alcohol (PVA) microneedles (MNs), addressing limitations of conventional micromoldi...