Neratinib-loaded solid lipid nanoparticles in dissolvable microneedles for enhanced transdermal breast cancer therapy [0.03%]
载有 Neratinib 的固脂纳米粒在可溶性微针中的应用及其经皮治疗乳腺癌的增效作用研究
Saraisam Kishor Kumar Singha,Venkatesh Dinnekere Puttegowda,Yousuf Elbini et al.
Saraisam Kishor Kumar Singha et al.
Neratinib, an FDA-approved drug for breast cancer, faces challenges such as poor solubility, limited permeability, and adverse side effects. To address these issues, we developed dissolving microneedles incorporating Neratinib-loaded solid ...
Isolation of bacterial extracellular vesicles from raw samples using a portable microstructured electrochemical device [0.03%]
利用便携式微结构电化学装置从原始样品中分离细菌胞外囊泡
Valeria Mantella,Siiri Bienz,Finn Brigger et al.
Valeria Mantella et al.
Bacterial extracellular vesicles (EVs) are nanosized vesicles released by both Gram-negative and Gram-positive bacteria, playing critical roles in microbial communication, host-pathogen interactions, and immune modulation. Despite their sig...
Controlled co-delivery of anti-inflammatory drugs from bilayer polymer films coating a meniscus implant [0.03%]
双层聚合物薄膜控制关节植入载药的协同控释研究
Alfonso F Blanco,Gustavo Lou,Alba Pensado-López et al.
Alfonso F Blanco et al.
Knee osteoarthritis (OA), a degenerative joint disease, is increasingly prevalent worldwide and often results from a meniscal deterioration that leads to meniscus removal. Replacing the damaged meniscus with a non-biodegradable prosthesis o...
Vitamin D-loaded lipid nanoparticles: antioxidant properties, preparation, optimization, and in vitro characterization [0.03%]
维生素D载脂质纳米粒的抗氧化性能、制备、优化及体外表征研究
Khadeejeh Al-Smadi,Mohammad Imran,Ayyah Abdoh et al.
Khadeejeh Al-Smadi et al.
Vitamin D3-loaded lipid nanoparticles (Vit D3-LNP), integrated into an azulene cream, were developed to enhance the topical delivery and stability of Vitamin D3. The LNP was formulated using a lipid mixture and hot homogenization-ultrasonic...
Asia Pacific Delivery Science Conference (APDSC) 2024 co-organised by the CRS Malaysia, Australia, Chinese Taipei and New Zealand Local Chapters [0.03%]
2024年亚太配送科学大会（APDSC）由马来西亚、澳大利亚、中国台北和新西兰当地分会联合举办
Choon Fu Goh,Ju Yen Fu,Tushar Kumeria et al.
Choon Fu Goh et al.
Critical evaluation of saponin as a permeabilizer for anandamide encapsulation in extracellular vesicles [0.03%]
皂苷作为外泌体中阿南达胺包封的透化剂的批判性评价
Marie Auquière,Romano Terrasi,Viridiane Gratpain et al.
Marie Auquière et al.
Extracellular Vesicles (EV) have received considerable attention as drug delivery systems. Research into the loading of various exogenous cargoes in EV has been expanding in recent years. While bioactive lipids are a class of highly interes...
Improved cognition and memory via PLGA nanoparticle-mediated delivery of curcumin and piperine in an in vivo Alzheimer's disease model [0.03%]
基于PLGA纳米粒子递送姜黄素和胡椒碱的阿尔茨海默病模型中的认知与记忆改善作用研究
Zhi Xin Phuna,Shantini Vijayabalan,Bibhu Prasad Panda et al.
Zhi Xin Phuna et al.
Alzheimer's disease (AD) is a multifactorial neurodegenerative disease that causes dementia, impaired cognitive function, and disorientation. Studies have revealed that curcumin and piperine were found to be neuroprotective for patients wit...
San San Amelia Tai,Hooi Leong Loo,Athirah Bakhtiar et al.
San San Amelia Tai et al.
Polymeric nanoparticle-mediated GBA1 gene therapy is neuroprotective in a preclinical model of Parkinson's disease [0.03%]
基于聚合物纳米粒的GBA1基因治疗在帕金森病模型中的神经保护作用
Mohit Kwatra,Gijung Kwak,Haolin Li et al.
Mohit Kwatra et al.
Plant-derived exosome-like nanovesicles: mechanisms and molecular understanding in neurological disorders with potential therapeutic applications [0.03%]
植物来源的类外泌体纳米囊泡：在神经疾病中的作用机制及分子机理和潜在治疗应用
Sevim Isik,Sedra Alhelwani,Aya Sahsahi et al.
Sevim Isik et al.
Exosomes are nano vesicles secreted by the cells that play an essential role in intercellular communication, enabling the transport of bioactive molecules, including proteins, lipids, and nucleic acids. Among them, plant-derived exosome-lik...