X-ray diffraction recording from a small amount of fibrous protein materials oriented by a micro shear-flow cell [0.03%]
微切力流变池取向的小量纤维蛋白材料的X射线衍射记录
Hiroyuki Iwamoto,Kazuhiro Oiwa,Kogiku Shiba et al.
Hiroyuki Iwamoto et al.
This paper describes a method for recording X-ray diffraction patterns from a small amount of fibrous protein materials while being oriented by using a micro shear-flow cell. This cell consists of two concentrically arranged glass tubes. Th...
Charge block-driven liquid-liquid phase separation: A mechanism of how phosphorylation regulates phase behavior of disordered proteins [0.03%]
电荷区块驱动的液-液相分离：磷酸化调控无序蛋白相行为的一种机制
Hisashi Shimamura,Hiroya Yamazaki,Shige H Yoshimura
Hisashi Shimamura
Phosphorylation regulates protein function by modulating stereospecific interactions between protein-protein or enzyme-ligand. On the other hand, many bioinformatics studies have demonstrated that phosphorylation preferably occurs in intrin...
Real-time imaging of human endothelial-to-hematopoietic transition in vitro using pluripotent stem cell derived hemogenic endothelium [0.03%]
利用多能干细胞来源的生血内皮细胞在体外实时成像人类内皮转造血过程
Yuriko Yoneda,Hisaya Kato,Yoshiro Maezawa et al.
Yuriko Yoneda et al.
During embryogenesis, human hematopoietic stem cells (HSCs) first emerge in the aorta-gonad-mesonephros (AGM) region via transformation of specialized hemogenic endothelial (HE) cells into premature HSC precursors. This process is termed en...
Analysis of the singularity cells controlling the pattern formation in multi-cellular systems [0.03%]
多细胞系统中控制模式形成的奇点细胞的分析
Kazuki Horikawa,Tatsuya Takemoto
Kazuki Horikawa
Model systems for discovering evolutionary singularity of bilaterian physiological regulation: lessons from studies on simple/primitive flatworms [0.03%]
借助简单/原始扁形动物研究发现两侧对称生物生理调节进化独特性的模式系统：来自研究的启示
Shunsuke Mori,Aoshi Kobayashi,Hirotaka Sakamoto et al.
Shunsuke Mori et al.
Rei Shirakawa,Yuto Kurata,Takaomi Sakai
Rei Shirakawa
Identification of the neural circuits in the brain regulating animal behavior and physiology is critical for understanding brain functions and is one of the most challenging goals in neuroscience research. The fruitfly Drosophila melanogast...
Search for singularity cells at the onset of brain disorders using whole-brain imaging [0.03%]
利用全脑成像在大脑疾病起始阶段寻找奇点细胞
Hitoshi Hashimoto,Takanobu Nakazawa
Hitoshi Hashimoto
A battle between two biological singularities: Immune response vs. cancer [0.03%]
免疫反应与癌症之战：两种生物学奇点的对抗
Tomoya Katakai,Taku Okazaki
Tomoya Katakai
In a post-growth multicellular organism, the phenomenon in which a small number of rare cells can be the starting point for inducing a dramatic change in the entire system is considered a "biological singularity." The immune response and ca...
Research on the molecular mechanism of singularity phenomenon in neurological disorders [0.03%]
神经元疾病独特性现象的分子机制研究
Hiroko Bannai,Akihiko Takashima,Yoshiyuki Soeda et al.
Hiroko Bannai et al.
Chromophore-assisted light inactivation of target proteins for singularity biology [0.03%]
用于奇点生物学的发色团辅助光线灭活靶蛋白技术
Hisashi Shidara,Susumu Jitsuki,Kiwamu Takemoto
Hisashi Shidara
Singularity phenomena are rare events that occur only with a probability of one in tens of thousands and yet play an important role in the fate of the entire system. Recently, an ultra-wide-field microscopy imaging systems, AMATERAS, have b...