The molecular dynamics of crawling migration in microtubule-disrupted keratocytes [0.03%]
微管崩解的角膜细胞爬行迁移的分子动力学研究
Hitomi Nakashima,Chika Okimura,Yoshiaki Iwadate
Hitomi Nakashima
Cell-crawling migration plays an essential role in complex biological phenomena. It is now generally believed that many processes essential to such migration are regulated by microtubules in many cells, including fibroblasts and neurons. Ho...
Satoru Okuda,Yasuhiro Inoue,Taiji Adachi
Satoru Okuda
During morphogenesis, various cellular activities are spatiotemporally coordinated on the protein regulatory background to construct the complicated, three-dimensional (3D) structures of organs. Computational simulations using 3D vertex mod...
Physicochemical origin of high correlation between thermal stability of a protein and its packing efficiency: a theoretical study for staphylococcal nuclease mutants [0.03%]
关于蛋白质热稳定性和其堆积效率之间高相关性的物理化学起源的理论研究——葡萄球菌核酸酶突变体的例子
Koji Oda,Masahiro Kinoshita
Koji Oda
There is an empirical rule that the thermal stability of a protein is related to the packing efficiency or core volume of the folded state and the protein tends to exhibit higher stability as the backbone and side chains are more closely pa...