Souhei Sakata,Makoto Matsuda,Akira Kawanabe et al.
Souhei Sakata et al.
Voltage-sensing phosphatase (VSP) consists of a transmembrane voltage sensor and a cytoplasmic enzyme region. The enzyme region contains the phosphatase and C2 domains, is structurally similar to the tumor suppressor phosphatase PTEN, and c...
Single-molecule fluorescence imaging of RalGDS on cell surfaces during signal transduction from Ras to Ral [0.03%]
来信号转导过程中的单分子荧光成像
Ryo Yoshizawa,Nobuhisa Umeki,Masataka Yanagawa et al.
Ryo Yoshizawa et al.
RalGDS is one of the Ras effectors and functions as a guanine nucleotide exchange factor for the small G-protein, Ral, which regulates membrane trafficking and cytoskeletal remodeling. The translocation of RalGDS from the cytoplasm to the p...
Kotomi Shibata,Tsubasa Koyama,Shohei Inde et al.
Kotomi Shibata et al.
The myosin II SH1 helix is a joint that links the converter subdomain to the rest of the myosin motor domain and possibly plays a key role in the arrangement of the converter/lever arm. Several point mutations within the SH1 helix in human ...
Molecular properties of a DTD channelrhodopsin from Guillardia theta [0.03%]
来源于Guillardia theta的DTD通道视紫红质的分子特性
Yumeka Yamauchi,Masae Konno,Shota Ito et al.
Yumeka Yamauchi et al.
Microbial rhodopsins are membrane proteins found widely in archaea, eubacteria and eukaryotes (fungal and algal species). They have various functions, such as light-driven ion pumps, light-gated ion channels, light sensors and light-activat...
Existence of two O-like intermediates in the photocycle of Acetabularia rhodopsin II, a light-driven proton pump from a marine alga [0.03%]
海洋藻类光驱动质子泵Acetabularia视紫红质II的光循环中存在两种O型中间体
Jun Tamogami,Takashi Kikukawa,Toshifumi Nara et al.
Jun Tamogami et al.
A spectrally silent change is often observed in the photocycle of microbial rhodopsins. Here, we suggest the presence of two O intermediates in the photocycle of Acetabularia rhodopsin II (ARII or also called Ace2), a light-driven algal pro...
Identification of aqueous access residues of the sodium half channel in transmembrane helix 5 of the Fo- a subunit of Propionigenium modestum ATP synthase [0.03%]
丙酸微生链丝菌ATP合酶中的Na+半通道在a亚基跨膜螺旋5中水接触残基的鉴定
Noriyo Mitome,Hiroki Sato,Taishi Tomiyama et al.
Noriyo Mitome et al.
The Fo-a subunit of the Na+-transporting FoF1 ATP synthase from Propionigenium modestum plays a key role in Na+ transport. It forms half channels that allow Na+ to enter and leave the buried carboxyl group on Fo-c subunits. The essential Ar...
Kinetic characteristics of chimeric channelrhodopsins implicate the molecular identity involved in desensitization [0.03%]
嵌合型通道视紫红质的动力学特性暗示其脱敏作用相关的分子身份
Alemeh Zamani,Shigeo Sakuragi,Toru Ishizuka et al.
Alemeh Zamani et al.
Channelrhodopsin (ChR)-1 and ChR2 were the first-identified members of ChRs which are a growing subfamily of microbial-type rhodopsins. Light absorption drives the generation of a photocurrent in cell membranes expressing ChR2. However, the...
Kazuya Suzuki,Takeshi Itabashi,Shin&#x;ichi Ishiwata
Kazuya Suzuki
The metaphase spindle is organized for accurate chromosome segregation. One of the fundamental features of the spindle across the species is its symmetrical shape; the spindle consists of two polar arrays of microtubules at both ends. Altho...
Actin binding domain of filamin distinguishes posterior from anterior actin filaments in migrating Dictyostelium cells [0.03%]
黏着斑在迁移的Dictyostelium细胞中区分后部和前部肌动蛋白丝的作用
Keitaro Shibata,Akira Nagasaki,Hiroyuki Adachi et al.
Keitaro Shibata et al.
Actin filaments in different parts of a cell interact with specific actin binding proteins (ABPs) and perform different functions in a spatially regulated manner. However, the mechanisms of those spatially-defined interactions have not been...
Ryuma Sato,Ryuhei Harada,Yasuteru Shigeta
Ryuma Sato
As for UV-induced DNA damage, which may induce skin cancer in animals and growth inhibition in plants, there are two types of photoproducts, namely cis-sin cyclobutane pyrimidine dimers (CPD) and pyrimidine-pyrimidone (6-4) photoproducts. W...