Assessment of occupational exposures to multiple metals with urinary porphyrin profiles [0.03%]
基于尿卟啉谱评估职业人群金属混合暴露水平
V Lopes de Andrade,M L Mateus,M Aschner et al.
V Lopes de Andrade et al.
Chronic occupational exposures to low levels of metal mixtures necessitates biomonitoring of exposed workers. However, a single biomarker (BM) is rarely sufficient to ascertain the exposure of an individual to a complex mixture, with multip...
Steven Halouska,Bo Zhang,Rosmarie Gaupp et al.
Steven Halouska et al.
Over the past decade, metabolomics has emerged as an important technique for systems biology. Measuring all the metabolites in a biological system provides an invaluable source of information to explore various cellular processes, and to in...
Marina Jerebtsova,Sergei Nekhai
Marina Jerebtsova
The effectiveness of treatment of renal diseases is limited because the lack of diagnostic, prognostic and therapeutic markers. Despite the more than a decade of intensive investigation of urinary biomarkers, no new clinical biomarkers were...
Optimisation of Downscaled Tandem Affinity Purifications to Identify Core Protein Complexes [0.03%]
优化亲和纯化技术鉴定核心蛋白复合体
Eric B Haura,Roberto Sacco,Jiannong Li et al.
Eric B Haura et al.
In this study we show that via stable, retroviral-expression of tagged EGFR del (L747-S752 deletion mutant) in the PC9 lung cancer cell line and stable doxycycline-inducible expression of tagged Grb2 using a Flp-mediated recombination HEK29...
Stephanie Byrum,Samuel G Mackintosh,Ricky D Edmondson et al.
Stephanie Byrum et al.
Central to the study of chromosome biology are techniques that permit the purification of small chromatin sections for analysis of associated DNA and proteins, including histones. Chromatin purification protocols vary greatly in the extent ...