The roles of tight junction protein cingulin in human endometrioid endometrial cancer [0.03%]
黏带蛋白在人子宫内膜样癌中的作用研究
Arisa Kura,Kimihito Saito,Takumi Konno et al.
Arisa Kura et al.
The bicellular tight junction molecule cingulin (CGN) binds to microtubules in centrosomes. Furthermore, CGN contributes to the tricellular tight junction (tTJ) proteins lipolysis-stimulated lipoprotein receptor (LSR) and tricellulin (TRIC)...
The stratum corneum barrier: impaired function in relation to associated lipids and proteins [0.03%]
角质层屏障：与相关脂质和蛋白质有关的功能障碍
Jie Chen,Changjie Liu,Yuan Yang et al.
Jie Chen et al.
The skin is the largest organ of the human body and is widely considered to be the first-line defense of the body, providing essential protection against mechanical, physical, and chemical damage. Keratinocytes are the primary cells of the ...
The role of reactive oxygen species in the regulation of the blood-brain barrier [0.03%]
反应性氧种类在血脑屏障调节中的作用
Margarita Shuvalova,Anastasiia Dmitrieva,Vsevolod Belousov et al.
Margarita Shuvalova et al.
The blood-brain barrier (BBB) regulates the exchange of metabolites and cells between the blood and brain, and maintains central nervous system homeostasis. Various factors affect BBB barrier functions, including reactive oxygen species (RO...
Deependra Singh,Saurabh Kumar,Rajnikant Mishra et al.
Deependra Singh et al.
The blood-testis barrier is a specialized feature within the mammalian testis, located in close proximity to the basement membrane of seminiferous tubules. This barrier serves to divide the seminiferous epithelium into distinct basal and ad...
Effects of small extracellular vesicles derived from normoxia- and hypoxia-treated prostate cancer cells on the submandibular salivary gland epithelium in vitro [0.03%]
体外正常氧和低氧处理的前列腺癌细胞源的小细胞外囊泡对颌下腺上皮的影响
Ana Špilak,Andreas Brachner,Heinz-Peter Friedl et al.
Ana Špilak et al.
Small extracellular vesicles (sEVs) are an important part of intercellular communication. They are phospholipid bilayer particles that carry active biomolecules such as proteins, various nucleic acids, and lipids. In recipient cells, sEVs c...
Molecular alterations in claudin 18 suppressed and non-suppressed gastric adenocarcinomas to guide targeted therapies [0.03%]
用于指导靶向治疗的Claudin 18阴性和阳性胃腺癌的分子改变
Ioannis A Voutsadakis
Ioannis A Voutsadakis
Background: Gastric adenocarcinoma represents an aggressive type of cancer and an important cause of cancer mortality. Progress in gastric cancer therapeutics has resulted from a better understanding of the molecular path...
Hyperglycaemia perturbs blood-brain barrier integrity through its effects on endothelial cell characteristics and function [0.03%]
高血糖通过其对内皮细胞特性和功能的影响破坏血脑屏障的完整性
Arshad Hashmat,Jingyuan Ya,Rais Kadir et al.
Arshad Hashmat et al.
Breakdown of blood-brain barrier (BBB) represents a key pathology in hyperglycemia-mediated cerebrovascular damage after an ischemic stroke. As changes in the level and nature of vasoactive agents released by endothelial cells (ECs) may con...
The correlation between fecal microbiota profiles and intracellular junction genes expression in young Iranian patients with celiac disease [0.03%]
伊朗年轻乳糜泻患者肠道菌群与细胞内桥基因表达的相关性研究
Mohadeseh Mahmoudi Ghehsareh,Nastaran Asri,Fahimeh Sadat Gholam-Mostafaei et al.
Mohadeseh Mahmoudi Ghehsareh et al.
Celiac disease (CD) is characterized by the disruption of the intestinal barrier integrity and alterations in the microbiota composition. This study aimed to evaluate the changes in the fecal microbiota profile and mRNA expressions of intra...
Spermine oxidase inhibitor, MDL 72527, reduced neovascularization, vascular permeability, and acrolein-conjugated proteins in a mouse model of ischemic retinopathy [0.03%]
Spermine氧化酶抑制剂MDL 72527降低缺血性视网膜病变小鼠模型中的新生血管、血管通透性和丙烯醛连接蛋白
Abdullah Alhumaid,Fang Liu,Shengshuai Shan et al.
Abdullah Alhumaid et al.
Disruptions in polyamine metabolism have been identified as contributing factors to various central nervous system disorders. Our laboratory has previously highlighted the crucial role of polyamine oxidation in retinal disease models, speci...
The connection between fatty acids and inflammation in celiac disease; a deep exploring [0.03%]
脂肪酸和乳糜泻炎症之间的关系；深入探究
Sajjad Bakhtiari,Nastaran Asri,Mahtab Jahdkaran et al.
Sajjad Bakhtiari et al.
The interplay between fatty acids (FAs) and celiac disease (CD) is a burgeoning field of research with significant implications for understanding the pathophysiology and potential therapeutic avenues for this autoimmune disorder. CD, trigge...