Involvement of vimentin intermediate filaments in overcoming tissue barriers during cancer cell dissemination [0.03%]
癌细胞转移过程中间丝蛋白波形蛋白参与克服组织屏障的作用
Anna O Zholudeva,Ekaterina A Kozlova,Natalya A Gloushankova et al.
Anna O Zholudeva et al.
The ability to overcome numerous tissue barriers during metastasis is a characteristic feature of tumor cells. This ability is acquired during tumor progression and represents a significant challenge for the development of therapeutic strat...
Mutational signatures in blood-brain barrier: mechanisms, computational insights, and clinical applications in precision oncology [0.03%]
血脑屏障中突变特征的机制、计算见解及其在精准肿瘤学中的临床应用
Hare Krishna,Vinod Kumar Singh,Seema Awasthi et al.
Hare Krishna et al.
The blood - brain barrier (BBB) plays a central role in maintaining central nervous system (CNS) homeostasis, and its disruption is a defining feature of malignant brain tumors such as glioblastoma. Emerging evidence indicates that BBB dysf...
Integrated transcriptomic and functional characterization of Claudin-1 reveals its oncogenic and immunomodulatory roles in pancreatic ductal adenocarcinoma [0.03%]
集成了转录组和功能特征的Claudin-1在胰腺导管腺癌中的致癌及免疫调节作用的综合研究
Anju Surendranath,Yogain Taank,Saira Hamid et al.
Anju Surendranath et al.
Pancreatic ductal adenocarcinoma (PDAC) remains among the deadliest malignancies, driven by its invasive nature and lack of effective biomarkers. Disruption of the epithelial barrier, mediated by tight junction components, is a critical yet...
Occludin deficiency is associated with developmental impairment, locomotor dysfunction, and social deficiencies [0.03%]
Occludin缺陷与发育障碍、运动功能障碍和社会行为缺陷有关
Silvia Torices,Nikolai Fattakhov,Oandy Naranjo et al.
Silvia Torices et al.
Neurodevelopmental and psychiatric disorders, such as attention deficit hyperactivity disorder or autism spectrum disorder, have been intricately linked to structural impairments and compromised permeability of the blood-brain barrier (BBB)...
Correction [0.03%]
改正
Published Erratum
Tissue barriers. 2026 Mar 9:2634592. DOI:10.1080/21688370.2026.2634592 2026
The gatekeepers breached: claudin dysregulation in psychiatric disorders [0.03%]
精神疾病中的屏障调节受损：闭合蛋白的作用
Tarek Ziad Arabi,Wael Alkattan,Belal Nedal Sabbah et al.
Tarek Ziad Arabi et al.
Psychiatric disorders such as depression, bipolar disorder, schizophrenia, and autism spectrum disorder are increasingly understood not only as disruptions in brain chemistry or circuitry but also as disorders of neural microenvironments an...
Permeation of small extracellular vesicles across a human blood-brain barrier transwell model remains below particle detection limits, even under oxygen/glucose deprived conditions [0.03%]
小细胞外囊泡难以透过人血脑屏障模型，即使在缺氧和葡萄糖缺乏条件下亦无法检出
Adrián Klepe,Sonja Damberger,Ana Špilak et al.
Adrián Klepe et al.
Ischemic stroke disrupts blood-brain barrier (BBB) integrity and alters small extracellular vesicle (sEV) signaling, yet the mechanisms underlying sEV transport across compromised barriers remain poorly understood. This study investigated B...
The oral mucosal barrier: a dynamic gateway in oral and systemic health [0.03%]
口腔黏膜屏障：口腔和全身健康之间的动态通道
Yuan Xin,Hu Lei
Yuan Xin
The oral mucosal barrier, the primary entry point for essential substances (water, food, air), is crucial for oral and systemic health. Comprising a salivary gel layer, commensal microbiota, stratified epithelia, underlying connective tissu...
Using mathematical approaches to answer complex biological questions: can exosomal miRnas predict cancer prognosis? [0.03%]
用数学方法解答复杂的生物学问题：癌胚小体微RNA能预测癌症预后吗？
Olka Missaghi,Leman Nur Nehri,Sepehr Bakhshi et al.
Olka Missaghi et al.
Epithelial to mesenchymal transition (EMT) has been widely implicated in diverse cellular processes such as development, would healing, as well as in cancer metastasis and therapy resistance. Exosomes are nanosized vesicles that carry cellu...
Aniket Gupta,Rishabh Chalotra,Kajal Sharma et al.
Aniket Gupta et al.
Diabetic foot ulcer (DFU) is a chronic and predominantly microvascular and neuropathic complication in more severe or chronic cases of diabetes mellitus. It is characterized by chronic nonhealing wounds, vascular impairment, and delayed hea...