A novel approach for lymphatic organoid embedding: eosin pre-staining and agarose pre-embedding [0.03%]
淋巴类器官包埋的一种新方法：伊红预染色和琼脂糖预包埋
Bao-Feng Wang,Ying-Ying Wang,Yun-Lan Yi et al.
Bao-Feng Wang et al.
Adenoid organoids, as the primary immune barrier of the airway, provide valuable models for studying lymphatic tissue function, but their histological processing remains challenging due to their fragile structure and lack of adhesion. Here,...
Modulating nasal barrier function and tissue remodeling in inflammatory diseases: the role of ginseng and its bioactive compounds [0.03%]
鼻炎性疾病中的人参及其生物活性成分对屏障功能及组织重塑的调节作用
Giovanna Lucia Piazzetta,Nadia Lobello,Corrado Pelaia et al.
Giovanna Lucia Piazzetta et al.
Ginseng, a well-known herbal supplement, is widely recognized for its pharmacological properties, including anti-inflammatory, antioxidant, and immune-modulatory effects. This review explores the potential therapeutic benefits of ginseng, p...
Frataxin deficiency and the pathology of Friedreich's Ataxia across tissues [0.03%]
_frataxin_的缺乏与弗瑞德里希共济失调症在各组织中的病理表现
Wesley S Ercanbrack,Mateo Ramirez,Austin Dungan et al.
Wesley S Ercanbrack et al.
Friedreich's Ataxia (FRDA) is a neurodegenerative disease that affects a variety of different organ systems. The disease is caused by GAA repeat expansions in intron 1 of the Frataxin gene (FXN), which results in a decrease in the expressio...
β-arrestin 1 and integrin-linked kinase interact in epidermal keratinocytes and regulate cell motility [0.03%]
β- Arrestin 1 和整联蛋白连接激酶在表皮角化细胞中相互作用并调节细胞运动性
Hannah Murphy-Marshman,Iordanka A Ivanova,Moshmi Bhattacharya et al.
Hannah Murphy-Marshman et al.
Arrestins and integrin-linked kinase (ILK) are important scaffold proteins that regulate myriad cell functions in metazoans. β-arrestins, first identified as critical components in G-protein-coupled receptor (GPCR) signaling pathways, part...
Ephrin-Eph signaling: an important regulator of epithelial integrity and barrier function [0.03%]
Ephrin-Eph信号传导：上皮完整性及屏障功能的重要调节因子
Mohan Liu,Joseph G Charek,Rodolfo D Vicetti Miguel et al.
Mohan Liu et al.
Eph receptor-interacting proteins (ephrin) ligands and their erythropoietin-producing human hepatocellular (Eph) receptors elicit bidirectional signals that regulate cell migration, angiogenesis, neuronal plasticity, and other developmental...
Size-selective permeation-enhancing modulation of the tight junction by receptor-binding domains of Clostridium perfringens enterotoxin and Clostridium perfringens iota-toxin [0.03%]
列表菌素和清单素 iota 毒素受体结合区对紧密连接的尺寸选择性渗透增强调节作用
Keisuke Tachibana,Sayaka Sugimura,Shuko Sakimura et al.
Keisuke Tachibana et al.
Modulation of claudin-based bicellular tight junction (TJ) and angulin-based tricellular TJ seals has been shown to enhance mucosal permeation of macromolecules, by using the receptor-binding fragments of Clostridium perfringens enterotoxin...
Fistula in Crohn's disease: classification, pathogenesis, and treatment options [0.03%]
克罗恩病肛瘘的分类、发病机制和治疗选择
Kimia Basiji,Nesa Kazemifard,Maryam Farmani et al.
Kimia Basiji et al.
Crohn's disease is a form of inflammation that affects the gastrointestinal (GI) tract. It is characterized by persistent inflammation in the gut, which can lead to the formation of abnormal connections called fistulas. These fistulas can o...
Cell-cell crosstalk in the pathogenesis of acute lung injury and acute respiratory distress syndrome [0.03%]
细胞通讯在急性肺损伤和急性呼吸窘迫综合症发病机制中的作用
Zhenzhen Zhu,Ying Zhang,Huan Chen et al.
Zhenzhen Zhu et al.
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are the result of an exaggerated inflammatory response triggered by a variety of pulmonary and systemic insults. The lung tissues are comprised of a variety of cell type...
Claudins in vulvar cancer - from epithelial barrier to potential tumor-agnostic cancer therapy [0.03%]
Claudins与外阴癌上皮屏障及潜在的肿瘤无关型癌症治疗的关系
Gilbert Georg Klamminger,Annick Bitterlich,Meletios P Nigdelis et al.
Gilbert Georg Klamminger et al.
The immunohistochemical expression of various members of the claudin family has already been studied in pathological affections of the vulva whether to differentiate precancerous lesions from vulvar squamous cell carcinoma or in inflammator...
Treatment with TNFα and lipolysis-stimulated lipoprotein receptor (LSR) antibody in the presence of HDAC inhibitors promotes apoptosis in human salivary duct adenocarcinoma [0.03%]
HDAC抑制剂存在时TNFα和LSR抗体治疗可促进人腮腺导管腺癌细胞凋亡
Soshi Nishida,Takumi Konno,Takayuki Kohno et al.
Soshi Nishida et al.
Lipolysis-stimulated lipoprotein receptor (LSR), a lipid metabolism-related factor localized in tricellular tight junctions (tTJs), plays an important role in maintaining the epithelial homeostasis. LSR is highly expressed in well-different...