Entamoeba histolytica: Host parasite interactions at the colonic epithelium [0.03%]
溶组织内阿米巴：结肠上皮的宿主寄生虫相互作用
Steve Cornick,Kris Chadee
Steve Cornick
Entamoeba histolytica (Eh) is the protozoan parasite responsible for intestinal amebiasis and interacts dynamically with the host intestinal epithelium during disease pathogenesis. A multifaceted pathogenesis profile accounts for why 90% of...
Paracellular transport as a strategy for energy conservation by multicellular organisms? [0.03%]
细胞间转运作为多细胞生物节能的策略吗？
Alan S L Yu
Alan S L Yu
Paracellular transport of solutes and water accompanies transcellular transport across epithelial barriers and together they serve to maintain internal body composition. However, whether paracellular transport is necessary and why it evolve...
Water transport through the intestinal epithelial barrier under different osmotic conditions is dependent on LI-cadherin trans-interaction [0.03%]
LI-钙粘蛋白介导的细胞间相互作用在不同渗透条件下调控肠上皮屏障的水转运功能
Agnes Weth,Carsten Dippl,Yasmin Striedner et al.
Agnes Weth et al.
In the intestine water has to be reabsorbed from the chymus across the intestinal epithelium. The osmolarity within the lumen is subjected to high variations meaning that water transport often has to take place against osmotic gradients. It...
Transport of germ cells across the seminiferous epithelium during spermatogenesis-the involvement of both actin- and microtubule-based cytoskeletons [0.03%]
生精过程中生殖细胞穿越生精上皮的作用机制--兼论以肌动蛋白和微管为基础的细胞骨架的作用
Qing Wen,Elizabeth I Tang,Xiang Xiao et al.
Qing Wen et al.
The transport of germ cells from the base of the seminiferous epithelium toward the luminal edge of the tubule lumen in the adluminal compartment during the epithelial cycle is an essential cellular event to support spermatogenesis. Thus, f...
Zonulin, a regulator of epithelial and endothelial barrier functions, and its involvement in chronic inflammatory diseases [0.03%]
zonulin：上皮和内皮屏障功能的调节因子及其在慢性炎症性疾病中的作用
Craig Sturgeon,Alessio Fasano
Craig Sturgeon
Beside digesting nutrients and absorbing solutes and electrolytes, the intestinal epithelium with its barrier function is in charge of a tightly controlled antigen trafficking from the intestinal lumen to the submucosa. This trafficking dic...
VE-cadherin complex plasticity: EPS8 and YAP play relay at adherens junctions [0.03%]
血管内皮钙粘蛋白复合体的可塑性：EPS8和YAP在粘着带处依次传递
Costanza Giampietro
Costanza Giampietro
The vascular endothelium is a selective barrier that separates the organs from the circulating blood. The endothelium has a wide variety of functions controlled by cell-to-cell junctions and in particular by Vascular Endothelial cadherin (V...
Regulation of endothelial and epithelial barrier functions by peptide hormones of the adrenomedullin family [0.03%]
肾上腺髓质素族肽激素对内皮和上皮屏障功能的调节作用
Alexander García-Ponce,Sandra Chánez Paredes,Karla Fabiola Castro Ochoa et al.
Alexander García-Ponce et al.
The correct regulation of tissue barriers is of utmost importance for health. Barrier dysfunction accompanies inflammatory disorders and, if not controlled properly, can contribute to the development of chronic diseases. Tissue barriers are...
CD73s protection of epithelial integrity: Thinking beyond the barrier [0.03%]
CD73对上皮完整性的保护作用：超越屏障的思考
Jessica L Bowser,Russell R Broaddus
Jessica L Bowser
The prevailing view of CD73 in cancer is that it is overexpressed in tumors and promotes cancer progression by dampening local T cell-mediated immune responses. We recently found that CD73 is down-regulated in poorly-differentiated and adva...
A proposed route to independent measurements of tight junction conductance at discrete cell junctions [0.03%]
一种在离散细胞连接处独立测量紧密连接电导的新方法的研究
Lushan Zhou,Yuhan Zeng,Lane A Baker et al.
Lushan Zhou et al.
Direct recording of tight junction permeability is of pivotal importance to many biologic fields. Previous approaches bear an intrinsic disadvantage due to the difficulty of separating tight junction conductance from nearby membrane conduct...
ClC-2 regulation of intestinal barrier function: Translation of basic science to therapeutic target [0.03%]
从基础研究到治疗靶点的肠道屏障功能调节因子ClC-2的研究进展
Younggeon Jin,Anthony T Blikslager
Younggeon Jin
The ClC-2 chloride channel is a member of the voltage-gated chloride channel family. ClC-2 is involved in various physiological processes, including fluid transport and secretion, regulation of cell volume and pH, maintaining the membrane p...