The intestinal quorum sensing 3-oxo-C12:2 Acyl homoserine lactone limits cytokine-induced tight junction disruption [0.03%]
肠道群体感应分子3-oxo-C12:2酰基霍姆塞因内酯限制了细胞因子诱导的紧密连接破坏
Doriane Aguanno,Garance Coquant,Barbara G Postal et al.
Doriane Aguanno et al.
The intestine is home to the largest microbiota community of the human body and strictly regulates its barrier function. Tight junctions (TJ) are major actors of the intestinal barrier, which is impaired in inflammatory bowel disease (IBD),...
Joseph M Chambers,Rebecca A Wingert
Joseph M Chambers
The kidney is a complex organ that performs essential functions such as blood filtration and fluid homeostasis, among others. Recent years have heralded significant advancements in our knowledge of the mechanisms that control kidney formati...
HMGB1 enhances epithelial permeability via p63/TGF-β signaling in lung and terminal bronchial epithelial cells [0.03%]
HMGB1通过p63/TGF-β信号通路增强肺和终末支气管上皮细胞的上皮通透性
Yuki Kodera,Takayuki Kohno,Takumi Konno et al.
Yuki Kodera et al.
High mobility group box 1 (HMGB1) is involved in the induction of airway inflammation and injury in patients with chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF). HMGB1 increased by transforming growth f...
Kim Natalie Stolte,Carsten Pelz,Cynthia V Yapto et al.
Kim Natalie Stolte et al.
Periodontitis is one of the most common oral diseases worldwide and is caused by a variety of interactions between oral bacteria and the host. Here, pathogens induce inflammatory host responses that cause the secretion of proinflammatory cy...
Correction [0.03%]
改正
Published Erratum
Tissue barriers. 2020 Apr 2;8(2):1784644. DOI:10.1080/21688370.2020.1784644 2020
Distribution pattern of ZO-1 and claudins in the epididymis of vampire bats [0.03%]
吸血蝙蝠附睾中ZO-1和claudins的分布模式
Mariana M Castro,Bongki Kim,Patrícia D Games et al.
Mariana M Castro et al.
Epithelial cells connect with each other by tight junctions (TJs) in several tissues. In epididymides, TJs proteins form the blood-epididymis barrier (BEB), which is crucial for male fertility. However, little is known about BEB morphologic...
DRM02, a novel phosphodiesterase-4 inhibitor with cutaneous anti-inflammatory activity [0.03%]
一种具有皮肤抗炎活性的新磷酸二酯酶-4抑制剂DRM02
David W C Hunt,Iordanka A Ivanova,Lina Dagnino
David W C Hunt
Chronic inflammatory skin disorders are frequently associated with impaired skin barrier function. Selective phosphodiesterase-4 (PDE4) inhibition constitutes an effective therapeutic strategy for the treatment of inflammatory skin diseases...
Lipid depletion enables permeation of Staphylococcus aureus bacteria through human stratum corneum [0.03%]
脂质耗尽可使金黄色葡萄球菌通过人体角质层
Zachary W Lipsky,Cláudia N H Marques,Guy K German
Zachary W Lipsky
Atopic dermatitis (AD) is a chronic inflammatory disease that affects approximately 2-5% of adults worldwide. The pathogenesis of AD continues to be a well-debated point of conjecture, with numerous hypotheses having been proposed. AD condi...
Optimization of an oral mucosa in vitro model based on cell line TR146 [0.03%]
基于TR146细胞系的体外口腔黏膜模型优化研究
Grace C Lin,Tamara Leitgeb,Alexandra Vladetic et al.
Grace C Lin et al.
During the last years, the popularity of saliva has been increasing for its applicability as a diagnostic fluid. Blood biomarker molecules have to cross the blood-saliva barrier (BSB) in order to appear in saliva. The BSB consists of all or...
HIV Tat-mediated induction of autophagy regulates the disruption of ZO-1 in brain endothelial cells [0.03%]
HIV蛋白Tat诱导的自噬调节脑内皮细胞ZO-1崩解
Ke Liao,Fang Niu,Guoku Hu et al.
Ke Liao et al.
The blood-brain barrier (BBB) is a tight barrier that is critical for preventing the entry of pathogens and small molecules into the brain. HIV protein Tat (Tat) is known to disrupt the tight junctions of the BBB. Autophagy is an intracellu...